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Category: biotech/medical – Page 122

Can we mobilise society towards a concerted effort against ageing? Dr Aubrey de Grey believes so—with groundbreaking results from studies by the Longevity Escape Velocity (LEV) Foundation on Integrative Rejuvenation, a cutting-edge approach to repairing cellular and molecular damage linked to ageing.

Why does he believe this could be the most promising pathway toward extending healthy human lifespan? Watch on to find out.

Register for upcoming #HealthyLongevity #webinar sessions at https://nus-sg.zoom.us/webinar/regist… The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material.

Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved.

All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain.

Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material.

Continue reading “Breaking the Pro-ageing Trance | Dr Aubrey de Grey” | >

An international team of scientists has unveiled new insights into the dissociation dynamics of sulfur hexafluoride (SF6) under high-energy X-ray excitation. The study, conducted using advanced synchrotron radiation techniques, sheds light on the formation of neutral sulfur atoms during the decay of deep core holes in SF6. The work is published in Physical Review Letters.

Understanding the interaction of X-rays with matter is fundamental to both scientific research and practical applications, including medical and technological advancements. These interactions involve complex processes including absorption, ionization, scattering, and the decay of excited states, which emit electrons or photons.

In 1978, young scientists named Joseph Nordgren and Hans Ågren discovered an unusual spectral feature in hexafluoride (SF6) that defied explanation at the time. Their discovery was made at the Siegbahn Laboratory of Uppsala University, founded by the late Nobel Prize laureate Kai Siegbahn. Despite further investigations, the nature of this spectral anomaly remained unclear.

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“ tabindex=”0” acid reflux at a significantly faster rate than those without. This highlights the urgent need for a healthcare system that treats both mental and physical health together, rather than in isolation.

Depression’s Lasting Impact on Physical Health

Adults with a history of depression develop chronic physical conditions about 30% faster than those without, according to a study published on February 13 in PLOS Medicine. Researchers, led by Kelly Fleetwood from the University of Edinburgh, suggest that depression should be recognized as a “whole-body” condition, emphasizing the need for integrated care that addresses both mental and physical health.

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The same material from which you drink your morning coffee could transform the way scientists detect disease, purify water, and insulate space shuttles thanks to an entirely new approach to ceramic manufacturing.

Published in Advanced Science, 3D-AJP is an aerosol jet 3D nanoprinting technique that allows for the fabrication of highly complex ceramic structures that—at just 10 micrometers (a fraction of the width of human hair)—are barely visible to the naked eye. These 3D structures are made up of microscale features including pillars, spirals, and lattices that allow for controlled porosity, ultimately enabling advances in ceramic applications.

“It would be impossible to machine ceramic structures as small and as precise as these using traditional manufacturing methods,” explained Rahul Panat, professor of mechanical engineering at Carnegie Mellon University and the lead author of the study. “They would shatter.”

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Mitochondrial stress disrupts insulinInsulin is a hormone produced by the pancreas, crucial for regulating blood glucose levels. It helps cells in the body absorb glucose from the bloodstream and convert it into energy or store it for future use. Insulin production and action are essential for maintaining stable blood sugar levels. In people with diabetes, the body either does not produce enough insulin (Type 1 diabetes) or cannot effectively use the insulin it does produce (Type 2 diabetes), leading to elevated levels of glucose in the blood. This can cause various health complications over time, including heart disease, kidney damage, and nerve dysfunction. Insulin therapy, where insulin is administered through injections or an insulin pump, is a common treatment for managing diabetes, particularly Type 1. The discovery of insulin in 1921 by Frederick Banting and Charles Best was a landmark in medical science, transforming diabetes from a fatal disease to a manageable condition. tabindex=0 insulin production in diabetes, but reversing the damage may restore β-cell function.

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A nonverbal autistic child said his first words after taking a cheap drug normally given to cancer patients.

Mason Conner of Arizona was diagnosed with autism at two-and-a-half-years-old after his mother noticed he hadn’t started talking.

After years of failed therapies and treatments, Mason’s parents met with a doctor researching experimental new therapies for autism.

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It’s a breakthrough in cancer treatment, and UChicago Medicine is one of the first hospitals to offer it.

It’s not just one treatment, but can eventually become a whole new way to treat cancer.

Alla Pinzour has been fighting skin cancer for around 15 years—but not anymore.

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Cells have surface receptors called integrins that bind to repetitive domains present on the extracellular matrix (ECM) surrounding the cells, allowing them to grow and spread. A new study from the Department of Bioengineering (BE), Indian Institute of Science (IISc) and collaborators shows that tweaking the spacing between these binding domains on the ECM can boost the efficiency of ultrasound treatment applied to kill cancer cells.

“In a normal tissue, the spacing on the ECM is around 50–70 nanometers (nm), but in the , severe choking occurs due to excessive ECM secretion, which may reduce the binding spacing to below 50 nm,” explains Ajay Tijore, Assistant Professor in BE and corresponding author of a related study published in Nano Letters. “We found more being killed when the binding spacing is increased to around 50–70 nm.”

Low-frequency ultrasound waves (39 kHz) can disrupt the and trigger cell death in cancer cells. It is a relatively low-cost and non-invasive approach. Unlike normal cells, cancer cells do not have repair mechanisms that help them withstand the exerted by ultrasound waves.

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