NIA-funded researchers identified areas of the genome responsible for accelerating or slowing down brain aging.
Category: biotech/medical – Page 1,305
AIIMS Bilaspur ties up with IIT Mandi for drone delivery of medicines
While the OPD has been thrown open to the people, work is going on war footing as PM Modi is expected to inaugurate the hospital early next month. The hospital already has 25 transport ventilators from the PM CARES fund.
Any person coming for treatment will only have to pay Rs 10 in registration charges for a lifetime and there are nominal charges for treatment.
AIIMS Bilaspur is set up with the objectives of correcting regional imbalances in the availability of affordable/reliable tertiary healthcare services and also to augment facilities for quality medical education in the country.
Researchers untangle the physics of high-temperature superconductors
When some materials are cooled to a certain temperature, they lose electric resistance, becoming superconductors.
In this state, an electric charge can course through the material indefinitely, making superconductors a valuable resource for transmitting high volumes of electricity and other applications. Superconductors ferry electricity between Long Island and Manhattan. They’re used in medical imaging devices such as MRI machines, in particle accelerators and in magnets such as those used in maglev trains. Even unexpected materials, such as certain ceramic materials, can become superconductors when cooled sufficiently.
But scientists previously have not understood what occurs in a material to make it a superconductor. Specifically, how high-temperature superconductivity, which occurs in some copper-oxide materials, works hasn’t been previously understood. A 1966 theory examining a different type of superconductors posited that electrons which spin in opposite directions bind together to form what’s called a Cooper pair and allow electric current to pass through the material freely.
Synthetic embryo grown without sperm, womb. It has a brain and a beating heart
In a new medical breakthrough, scientists have successfully grown a synthetic embryo of a mouse without male sperm and a female womb. They used stem cells from mice to recreate the first stage of life and successfully developed an embryo with a brain, beating heart, and vitals for other organs.
The natural process of life was mimicked in the lab without eggs or sperm but with the body’s master cells, which can develop into almost any cell type in the body. The embryo was developed 8 ½ days after fertilization, containing the same structures as a natural one.
The study published in the journal Nature states that their result demonstrates the self-organization ability of embryonic and two types of extra-embryonic stem cells to reconstitute mammalian development. The researchers induced expression of a particular set of genes and established a unique environment for their interactions and got the stem cells to ‘talk’ to each other.
Existential Hope Special with Morgan Levine | On the Future of Aging
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Program & apply to join: https://foresight.org/existential-hope/
In the Existential Hope-podcast (https://www.existentialhope.com), we invite scientists to speak about long-termism. Each month, we drop a podcast episode where we interview a visionary scientist to discuss the science and technology that can accelerate humanity towards desirable outcomes.
Xhope Special with Foresight Fellow Morgan Levine.
Morgan Levine is a ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work relies on an interdisciplinary approach, integrating theories and methods from statistical genetics, computational biology, and mathematical demography to develop biomarkers of aging for humans and animal models using high-dimensional omics data. As PI or co-Investigator on multiple NIH-, Foundation-, and University-funded projects, she has extensive experience using systems-level and machine learning approaches to track epigenetic, transcriptomic, and proteomic changes with aging and incorporate.
this information to develop measures of risk stratification for major chronic diseases, such as cancer and Alzheimer’s disease. Her work also involves development of systems-level outcome measures of aging, aimed at facilitating evaluation for geroprotective interventions.
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Small devices letting patients collect diagnostics quality blood samples
Small devices letting patients collect diagnostics quality blood samples at home were getting lots of publicity in the past few months, as they are finding their way into clinical trials and are available as direct-to-consumer products. We asked Dr Erwin Berthier, CTO and Co-Founder of Tasso about the technology.
You can read the exclusive interview on our Patreon page. Thank you for your support!
Reversed Halo Sign in Invasive Pulmonary Fungal Infections
face_with_colon_three circa 2008.
Opportunistic fungal pneumonias are associated with high morbidity and mortality rates [ 1–3]. Although invasive pulmonary aspergillosis (IPA) is the most common type of fungal pneumonia, other angioinvasive molds, such as Fusarium and Zygomycetes species, are increasingly encountered in severely immunocompromised hosts. Because early institution of high-dose antifungal therapy is associated with improved outcomes [ 4, 5], early recognition of invasive fungal disease is important. However, cultures of respiratory secretions are neither sensitive nor specific, and lavage and invasive procedures often cannot be done for these patients because of coagulation abnormalities and thrombocytopenia [ 6, 7]. Thus, diagnosis of invasive pulmonary fungal disease relies heavily on imaging [ 8]. CT is often used in an attempt to identify fungal pneumonia in a timely fashion.
The reversed halo sign (RHS) is a CT finding, a focal round area of ground-glass attenuation surrounded by a ring of consolidation, which has been described in cryptogenic organizing pneumonia [ 9, 10].
The purpose of the present study was to evaluate whether the RHS is evident on CT images of patients with invasive fungal pulmonary infections, the prevalence of RHS, and whether RHS can serve as an early sign of infection.
