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Category: biotech/medical – Page 1,476

Stresses and hydrodynamics: Scientists uncover new organizing principles of the genome

A team of scientists has uncovered the physical principles—a series of forces and hydrodynamic flows—that help ensure the proper functioning of life’s blueprint. Its discovery provides new insights into the genome while potentially offering a new means to spot genomic aberrations linked to developmental disorders and human diseases.

“The way in which the is organized and packed inside the nucleus directly affects its biological function, yet the physical principles behind this organization are far from understood,” explains Alexandra Zidovska, an associate professor in New York University’s Department of Physics and an author of the paper, which appears in the journal Physical Review X (PRX). “Our results provide fundamental insights into the biophysical origins of the organization of the genome inside the .”

“Such knowledge is crucial for understanding the genome’s function,” adds David Saintillan, a professor at the University of California San Diego’s Department of Mechanical and Aerospace Engineering and an author of the paper.

Science Confirms Our Life Really Does Flash Before Your Eyes Before Death

Death is perhaps one of the most universally discussed topics across the board, and at least once in our lives, the vast majority of us wonder what happens during our final moments. For a long time, we haven’t had many answers, well, that is until now.

One of the most common ‘rumors’ about death is that right before our final moment, our life flashes before our eyes. And recent research may offer some interesting answers that indicate this theory isn’t far from the truth.

The research was carried out by accident, as they had intended to study the brainwaves of an 87-year-old patient with epilepsy. However, during their research, the patient ended up suffering from a fatal heart attack. During the death of the patient, their brainwaves were recorded up until the moment of death.

Scientists use machine learning to get an unprecedented view of small molecules

A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry. Developed by researchers at Aalto University and the University of Luxembourg, the model was trained with data from dozens of laboratories to become one of the most accurate tools for identifying small molecules.

Thousands of different small molecules, known as , transport energy and transmit cellular information throughout the human body. Because they are so small, metabolites are difficult to distinguish from each other in a blood sample analysis—but identifying these molecules is important to understand how exercise, nutrition, and metabolic disorders affect well-being.

Metabolites are normally identified by analyzing their mass and retention time with a separation technique called liquid chromatography followed by mass spectrometry. This technique first separates metabolites by running the sample through a column, which results in different flow rates—or retention times—through the measurement device.

How a common cold develops

Winter and rainy season is worst for those who have low immunity. Antibiotics have many side effects. But there high fever due to viral infection is also risky.

A cold is an infection caused by a virus. It’s a common and usually mild illness that affects the nose and throat. Find out more here: http://bit.ly/KV8y1c.

The content is intended for general information only and does not replace the need for personal advice from a qualified health professional.

Origins of Rare Childhood Cancer-Like Disease Identified

Until now, some researchers believed Langerhans cell histiocytosis (LCH), a rare and fatal form of cancer in children, is derived from immune cells called dendritic cells, while others believed that they originate from related immune cells called monocytes. A new study showed mutated LCH cells have properties similar to both monocytes and dendritic cells, as well as a relatively new type of dendritic cell called DC3.

FDA Approves Gene Therapy for Tough-to-Treat Bladder Cancer

MONDAY, Dec. 19, 2022 (HealthDay News) — Patients with a high-risk bladder cancer now have a new option to treat it.

The U.S. Food and Drug Administration on Friday approved a gene therapy called Adstiladrin, which is designed to work for patients who have what’s called high-risk non-muscle-invasive bladder cancer (NMIBC) that hasn’t responded to the standard treatment, Bacillus Calmette-Guérin (BCG), but hasn’t spread. BCG is a vaccine typically used for tuberculosis.

“This approval provides health care professionals with an innovative treatment option for patients with high-risk NMIBC that is unresponsive to BCG therapy,” Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an agency news release. “Today’s action addresses an area of critical need. The FDA remains committed to facilitating the development and approval of safe and effective cancer treatments.”

New FDA-Approved Eyedrops Could Improve Close-Up Vision

Dec. 14, 2021 — A new FDA-approved eyedrop medicine could replace reading glasses for millions of Americans who have age-related blurry vision.

The product, called Vuity, was approved by the FDA in October and went on the market last week. The new medicine begins working in about 15 minutes and provides sharper vision for 6 to 10 hours.

Vuity is the first FDA-approved eyedrop to treat the condition known as presbyopia, which tends to affect people ages 40 and older. The prescription drug uses the eye’s natural ability to reduce its pupil size.

Life-changing: New gene therapy gel heals decades-old wounds from skin disease

A gene therapy gel for a blistering skin disease developed at Stanford Medicine has worked wonders in a double-blind, placebo-controlled clinical trial.

The gel, called B-VEC, was intended to treat dystrophic epidermolysis bullosa, a skin disease that results in large open wounds that last for decades. The condition is extremely painful, and the medical treatment is mostly limited to palliative care.

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