Jun 25, 2024
Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems
Posted by Dan Breeden in categories: biotech/medical, genetics, neuroscience
The mechanisms underlying human cell diversity are unclear. Here the authors provide a single-cell epigenome map of human neural organoid development and dissect how epigenetic changes control cell fate specification from pluripotency to distinct cerebral and retina neural types.