Lifeboat Foundation

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Ariel Schwartz — Fast Company

BPM 31510 is just another cancer drug in human development trials, except for one thing. Scientists didn’t toil away in labs to come up with it; artificial intelligence did.

The cancer drug development process is costly and time-consuming. On average, it takes 24 to 48 months and upwards of $100 million to find a suitable candidate. Add that to the fact that 95% of all potential drugs fail in clinical trials, and the inefficiencies of the whole drug-discovery machine really become apparent.

Backed by real estate billionaire Carl Berg, eponymous biotech startup Berg wants to use artificial intelligence to design cancer drugs that are cheaper, have fewer side effects, and can be developed in half the time it normally takes. BPM 31510 is the first of Berg’s drugs to get a real-world test.

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By Suzanne Jacobs — MIT Technology Review

Last week Google and Novartis announced that they’re teaming up to develop contact lenses that monitor glucose levels and automatically adjust their focus. But these could be just the start of a clever new product category. From cancer detection and drug delivery to reality augmentation and night vision, our eyes offer unique opportunities for both health monitoring and enhancement.

“Now is the time to put a little computer and a lot of miniaturized technologies in the contact lens,” says Franck Leveiller, head of research and development in the Novartis eye care division.

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Written By: Arlington Hewes — Singularity Hub

Absent an outright cure, it’s thought that early diagnosis of terminal diseases like cancer make treatment more effective and raise the probability of survival. But diagnosis is not always straightforward and often requires costly and invasive tests.

Simple, cheap, and accurate tests looking for the markers of disease may help.

One such method may be a blood test for cancer from University of Bradford researchers. The Lymphocyte Genome Sensitivity (LGS) test observes how DNA in lymphocytes (a type of white blood cell) is damaged under varying intensities of ultraviolet (UV) light.

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Anders Sandberg, a member of the advisory board for the Lifeboat Foundation, recently took part in a panel debate on the future of human cloning produced by the Institute of Art and Ideas.

Debate blurb:

Human cloning is anathema to most of us conjuring up Metropolis visions of identical humans serving tyrannical masters. But might this be a mistaken horror story? Could human cloning instead lead to medical breakthroughs and the end to infertility?

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Written By: Jason Dorrier — Singularity Hub

Robots come in all shapes and sizes—some are mechanical, and some aren’t. Last year, a team of scientists from the University of Illinois at Urbana-Champaign made a seven-millimeter-long 3D printed robot powered by the heart cells of a rat.

The device, made of 3D printed hydrogel—a water-based, biologically compatible gel—had two feet, one bigger than the other. The smaller, longer foot was coated in heart cells. Each time the cells contracted, the robot would crawl forward a few millimeters.

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BySarah Fecht- Popular Science

Eight years ago, doctors took nasal tissue samples and grafted them onto the spines of 20 quadriplegics. The idea was that stem cells within the nasal tissue might turn into neurons that could help repair the damaged spinal cord, and the experiment actually worked a few of the patients, who regained a little bit of sensation. But it didn’t go well for one woman in particular, who not only didn’t experience any abatement in her paralysis, but recently started feeling pain at the site of the implant. When doctors took a closer look, they realized she was growing the beginnings of a nose on her spine, New Scientist reports.

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Written By: Cameron Scott — Singularity Hub

For the recorder of potentially breakthrough medical technology, sometimes it seems that the list is just so many applications of three new technologies: smaller electronics, new materials and stem cells. Any electronic device set up to function inside the body relies on smaller, flexible parts and new biocompatible casings, for example. Stem cells, properly manipulated, seem capable of mending nearly everything that ails us.

But the details of how best to cultivate certain kinds of cells and spur them to function in the body are still being worked out. According to University of Rochester researchers, materials science may be a big help.

One trouble with stem cells is that they don’t stay put. When doctors put cardiovascular progenitor cells in the heart to heal damage from a heart attack, the cells are whisked away in the bloodstream in a matter of hours.

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