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The FDA has approved a new targeted drug specifically for brain tumors called low-grade gliomas. The drug, vorasidenib, was shown in clinical trials to delay progression of low-grade gliomas that had mutations in the IDH1 or IDH2 genes.

“Although there have been other targeted therapies for the treatment of brain tumors with the IDH mutation, [this one] has been one of the most successful in survival prolongation of brain tumor patients,” said Darell Bigner, MD, PhD, the E. L. and Lucille F. Jones Cancer Distinguished Research Professor and founding director of the Preston Robert Tisch Brain Tumor Center at Duke.

In clinical trials, progression-free survival was estimated to be 27.7 months for people in the vorasidenib group versus 11.1 months for those in the placebo group.

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A team of engineers and scientists from Caltech and the Keck School of Medicine at USC has created a noninvasive, headset-based device that can assess a patient’s stroke risk by monitoring blood flow and volume changes during a breath-holding test.

The device uses a laser-based system and has demonstrated promising results in distinguishing between individuals with low and high stroke risk.

“With this device, for the first time, we are going to have a way of knowing if the risk of someone having a stroke in the future is significant or not based on a physiological measurement,” says Simon Mahler, a co-lead author of the study.

A new biohybrid robot can be steered left, right, or straight by activating neurons and muscle cells embedded into its fins.

A Spanish biotech company sees the carbon material as a way to power the brain-computer interfaces of the future.

Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins.

“Not only are we delivering the protein in a more controlled way through a nanoparticle, but the compositional structure of this particle is also acting as an adjuvant,” Jaklenec says. “We were able to achieve very specific responses to the Covid protein, and with a dose-sparing effect compared to using the protein by itself to vaccinate.”

Vaccine access

Continue reading “MIT scientists use a new type of nanoparticle to make vaccines more powerful” »

A key aspect of human factors in robotic surgery is the training and proficiency of the surgeon. Robotic systems, although designed to enhance precision, rely heavily on the expertise of the individuals operating them. Companies should invest in comprehensive training programs that extend beyond basic certification and promote a culture of continuous learning and skill development.

Simulation-based training, for example, provides a risk-free environment for practicing complex procedures, helping surgeons build confidence and proficiency. Implementing standardized certification processes ensures consistent competency levels among surgeons.

DOOM has been ported to quantum computers, marking another milestone for this seminal 3D gaming title. However, the coder behind this feat admits that there is currently no quantum computer capable of executing (playing) this code right now. All is not lost, though, as Quandoom can run on a classical computer, even a modest laptop, using a lightweight QASM simulator.

Barcelona ICFO-based Quantum Information PhD student Luke Mortimer, AKA Lumorti, is behind this newest port of DOOM. In the ReadMe file accompanying the Quandoom 1.0.0 release, Lumorti quips that “It is a well-known fact that all useful computational devices ever created are capable of running DOOM,” and humorously suggests that Quandoom may be the first practical use found for quantum computers.

To make sense of the world around us, the brain must process an…

Neurons in certain brain areas integrate ‘what’ and ‘when’ information to discern hidden order in events happening in real time.

By Miryam Naddaf & Nature magazine

Continue reading “How Your Brain Detects Patterns without Conscious Thought” »