Lifeboat Foundation

Neuroplasticity is the brain’s ability to change under the influence of experience and activities. Several aspects of neuroplasticity are noteworthy: neurogenesis (development of new nerve cells) and synaptogenesis (development of new contacts between nerve cells) among them. Neuroplasticity used to be thought of as a limited phenomenon, mostly restricted to the early years of life. More recently it has been demonstrated that neuroplasticity continues throughout life, even in advanced age. This provides the conceptual basis for a wide range of therapeutic efforts aiming to slow the detrimental effects of aging on the brain and to treat various brain disorders.

What are the factors influencing neuroplasticity? The question is compelling both as a scientific challenge and because of the therapeutic promise of neuroplasticity once we know how to control and harness it. Among such factors, the environmental factors influencing neuroplasticity are particularly intriguing. It turns out that a strong relationship exists between what people do with their brains and how their brains age.

Both anecdotal observations and formal research suggest that education confers a protective effect against dementia. Highly educated people are less likely to succumb to its effects. Robert Katzman was the first to note that the prevalence of dementia, including Alzheimer’s disease, is lower in people with advanced education. The MacArthur Foundation Research Network on Successful Aging sponsored a study of the predictors of cognitive change in older persons. Education emerged as by far the most powerful predictor of cognitive vigor in old age.

‘s COVID-19 reporting is supported by the Pulitzer Center.

A group of prominent academic scientists that has been advising the U.S. government on security matters since the Cold War is conducting a quick-turnaround, pro bono study of a new threat to national security—the impact of COVID-19 on academic research. And this time it’s personal.

Last month, some 30 members of Jason began to tackle the thorny question of how to reopen university laboratories safely in the midst of the coronavirus pandemic. Nobody is paying for the study, a rare departure for the group, whose work is usually financed by government agencies and often involves classified information. But the study’s leader, Massachusetts Institute of Technology (MIT) physicist Peter Fisher, says several federal agencies have expressed interest in the group’s analysis of the technical challenges facing every university that wants to resume research operations without jeopardizing the health of the faculty, students, and staff who work in those labs.

Plant scientists have long known that crop yield is proportional to the dose of nitrogen fertilizer, but the increased use of fertilizers is costly and harmful to the environment. Until now, the underlying mechanisms by which plants adjust their growth according to the nitrogen dose has been unknown—a key finding that could help enhance plant growth and limit fertilizer use.

In a new study published in the Proceedings of the National Academy of Sciences (PNAS), plant genomic scientists at New York University’s Center for Genomics & Systems Biology discovered the missing piece in the molecular link between a plant’s perception of the nitrogen dose in its environment and the dose-responsive changes in its biomass.

Taking a novel approach, the NYU researchers examined how increasing doses of nitrogen created changes in plants’ genome-wide expression as a function of time. They then used mathematical models to investigate the rate of change of messenger RNA (mRNA) for thousands of genes within the genome to this experimental set up.

Crucially, plasma treatment of the old rats reduced the epigenetic ages of blood, liver and heart by a very large and significant margin, to levels that are comparable with the young rats. According to the six epigenetic clocks, the plasma fraction treatment rejuvenated liver by 73.4%, blood by 52%, heart by 52%, and hypothalamus by 11%. The rejuvenation effects are even more pronounced if we use the final versions of our epigenetic clocks: liver 75%, blood 66%, heart 57%, hypothalamus 19%. According to the final version of the epigenetic clocks, the average rejuvenation across four tissues was 54.2%.

Researchers have demonstrated that epigenetic age can be halved in rats by using signals commonly found in the blood.

Epigenetic changes

Continue reading “Blood Factors Reverse Epigenetic Age” »

Men’s blood has higher levels than women’s of a key enzyme used by the new coronavirus to infect cells, the results of a big European study showed on Monday — a finding which may help explain why men are more vulnerable to infection with COVID-19. One of the strongest biomarkers, ACE2, was much higher in men than in women…

LONDON (Reuters) — Men’s blood has higher levels than women’s of a key enzyme used by the new coronavirus to infect cells, the results of a big European study showed on Monday — a finding which may help explain why men are more vulnerable to infection with COVID-19.

Researchers from the University of Utah are developing a system that allows amputees to control a bionic arm using just their thoughts. What’s more, the hand portion of the limb enables them to ‘feel’ objects that are being touched or grasped. Known as the Luke Arm (a tribute to Luke Skywalker’s prosthetic limb), the robotic arm mimics the way a human hand feels different objects by sending signals to the brain. An amputee wearing the arm can sense how hard or soft an object is, letting them understand how best to handle said objects.

Nanotechnology is the application of science at a truly nano scale. To put that in perspective, if a nanometre were the size of a cup of tea, a meter would cover the diameter of the whole Earth.

Being able to control the world at such an intricate level has the potential to revolutionise medicine – enabling us to target cancer cells, deliver drugs and fight antibiotic resistance – but how do we create technology to that size?

Sonia talks to our editorial assistant Amy Barret about how her work in nanotechnology began, building proteins unknown to nature, and why going nano is nothing like in the movies.

Stem Cell Neurotherapy sends therapeutic messages, e.g., “your stem cells are transforming into new cells for the lungs, liver, and kidneys” to the DNA inside the nucleus of stem cells. Inside the nucleus, the DNA receives the message and transmits it to the RNA, which translates the message into genetic code.

The genes inside the stem cells transmit the coded message to the proteins, which are converted by the mitochondria into ATP, which provides the energy for the coded message to transform the stem cells into a new set of lung cells, as well as new cells for the kidneys and liver.

These new cells in the lungs, kidneys, and liver will replace the cells that were infected by the COVID-19 virus. This results in the elimination of the coughing, fever, headaches, diarrhea, and breathing problems.

Continue reading “Stem cell treatment in the UAE sees ‘favorable’ outcomes for coronavirus patients” »

One leader says there’s only one positive case of coronavirus on his reservation because of the checkpoints.