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Archive for the ‘biotech/medical’ category: Page 1614

Apr 14, 2020

Hyperbaric Application to COVID-19 Pulmonary Infection

Posted by in category: biotech/medical

In the midst of the coronavirus epidemic/pandemic it bears remembering the application of hyperbaric oxygen therapy to the last major pandemic that impacted the United States in 1918, the Spanish Flu Pandemic. Death was primarily by pulmonary infection and its attendant hypoxemia and respiratory failure. The first application of hyperbaric medicine to a Spanish Flu victim was likely also the first application to a human being in the United States. In 1918 Dr. Orval Cunningham of Kansas City was brought a dying friend of a fellow physician. The patient was moribund and blue. Before Cunningham could perform his planned animal experiments he was asked to treat this dying patient. With just a one-hour treatment with compressed air at 1.68 atmospheres absolute the patient experienced improvement. Combined with additional hyperbaric treatments over the next 3 days this patient’s life was saved. Others followed.

Today’s coronavirus’ mortality is due to pulmonary infection and respiratory failure. While there are differences between the Spanish Flu and coronavirus the primary pathology is in the lungs, the first organ of contact with hyperbaric therapy beyond the skin. The ability of hyperbaric oxygen to penetrate inflammatory pulmonary secretions allows adequate oxygen to reach the blood while inhibiting the inflammatory process. Applied correctly, hyperbaric therapy may have utility in coronavirus patients similar to its life-saving history with the Spanish Flu. Harch Hyperbarics Inc 504 309‑4948 www.hbot.com

Apr 14, 2020

Doctors Suspect Mystery COVID-19 Lung Problems, Plea for New Approach

Posted by in category: biotech/medical

Some doctors are questioning the way ventilators are being used for people with serious cases of COVID-19. Why? More data shows a high death rate for patients treated under current ventilator practices.

At the same time, these doctors are saying their patients behave more like they have high altitude sickness than a viral infection. They talk about two different types of COVID-19 patients with differing severe lung problems.

While some patients respond to treatment as expected, doctors also describe patients whose lungs seem relatively fine, but who still can’t get enough oxygen into their blood. These patients may make up the majority with severe infections.

Apr 14, 2020

The deadly germ warfare island abandoned by the Soviets

Posted by in categories: biotech/medical, military

During the Cold War, Vozrozhdeniya Island was a top-secret testing ground for deadly Soviet super-pathogens. Despite over two decades of abandonment, their legacy lives on.

Apr 14, 2020

Adaptive Biotech’s deal with Amgen influenced by belief that COVID-19 may return seasonally, like flu

Posted by in category: biotech/medical

Despite a potential vaccine, the novel coronavirus could return on a seasonal basis, much like the flu, according to Seattle-based company Adaptive Biotechnologies.

That’s one of the reasons Adaptive is teaming up with pharmaceutical giant Amgen, which plans to use Adaptive’s proprietary technology platform to develop therapies to treat the virus.

Adaptive’s CEO Chad Robins says it’s the next big thing in the field of immune sequencing. They will screen blood samples of COVID-19 survivors, then identify which naturally occurring antibodies in the immune system can be used to neutralize the SARS-CoV-2 virus which causes the disease.

Apr 14, 2020

Hokkaido declares new state of emergency amid ‘second wave’ of coronavirus infections

Posted by in categories: biotech/medical, government

While Hokkaido was not covered in the state’s declaration of an emergency, the prefectural government and the municipal government of Sapporo, the prefectural capital, issued a joint emergency declaration following reports of double-digit increases in infections for the fifth straight day.

“We are facing a crisis of a second wave in the spread of (the coronavirus) infections,” Hokkaido Gov. Naomichi Suzuki told reporters, asking residents to refrain from making nonessential outings.

Hokkaido had declared its own state of emergency on Feb. 28 ahead of the government and lifted it on March 19, citing signs that the coronavirus spread was abating in the prefecture, a popular area for both Japanese and foreign tourists.

Apr 13, 2020

Pope Francis: ‘This may be the time to consider a universal basic wage’

Posted by in categories: biotech/medical, economics, employment

Talk of a universal basic income (UBI), or regular cash payments with minimal or no requirements for receiving the money, has been brought to the forefront as social distancing and economic concerns have put millions of people out of work.


Amid the COVID-19 pandemic Pope Francis says it might be time for some sort of universal basic income.

“This may be the time to consider a universal basic wage” to “acknowledge and dignify the noble, essential tasks” and to “achieve the ideal … of no worker without rights,” Pope Francis said in a letter to the World Meeting of Popular Movements, an organization representing global grassroots organizations, published on Sunday via the Vatican.

Continue reading “Pope Francis: ‘This may be the time to consider a universal basic wage’” »

Apr 13, 2020

The role of global cooperation in space after COVID-19

Posted by in categories: biotech/medical, business, education, food, government, health, neuroscience

The coronavirus pandemic has resulted in the deaths of tens of thousands of people across the globe. It is also causing huge damage to the global economy. According to the predictions of the International Monetary Fund (IMF), 2020 could be the worst year since the Great Depression in the 1930s, with more than 170 countries likely to experience negative per capita income growth due to the pandemic. Countries are taking different measures to mitigate that economic impact, depending on the situations in their countries. However, the process of overcoming economic crisis is going to be extremely difficult. Few businesses would find it hard even to sustain and there is going to be a significant upsurge in unemployment rates.

Like much of the rest of the world, India is under lockdown. It is bit premature to predict the exact impact of coronavirus crisis on the Indian economy since the situation is still evolving. However, it is clear at this stage that the country will be facing major economic downturn and levels of unemployment will steeply rise. The government has already offered an economic package of 1.7 trillion rupees ($22.3 billion) in the last month for providing food security and money to the poor. It is expected that the government would shortly announce the next economic stimulus package.

All this would require the government of India to undertake a ruthless review of existing patterns of expenditure. The government budgeting caters to the requirements of various segments of the society, including agriculture, health, education, and railways. The budget has two other important areas of attention: defense and science & technology.

Apr 13, 2020

Virology lab finds drug originally meant for Ebola is effective against a key enzyme of coronavirus that causes COVID-19

Posted by in categories: biotech/medical, chemistry

Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published today in the Journal of Biological Chemistry.

The paper follows closely on research published by the same lab in late February that demonstrated how the drug worked against the Middle East Respiratory Syndrome (MERS) virus, a related coronavirus.

“We were optimistic that we would see the same results against the SARS-CoV-2 virus,” said Matthias Götte, chair of medical microbiology and immunology at U of A.

Apr 13, 2020

Nutrition interventions for healthy ageing across the lifespan: a conference report

Posted by in categories: biotech/medical, education, food, life extension, neuroscience, policy

Interventions that may slow ageing include drugs (e.g., rapamycin, metformin), supplements (e.g., nicotinamide riboside, nicotinamide mononucleotide), lifestyle interventions (e.g., exercise) and diets (e.g., fasting)


Thanks to advances in modern medicine over the past century, the world’s population has experienced a marked increase in longevity. However, disparities exist that lead to groups with both shorter lifespan and significantly diminished health, especially in the aged. Unequal access to proper nutrition, healthcare services, and information to make informed health and nutrition decisions all contribute to these concerns. This in turn has hastened the ageing process in some and adversely affected others’ ability to age healthfully. Many in developing as well as developed societies are plagued with the dichotomy of simultaneous calorie excess and nutrient inadequacy. This has resulted in mental and physical deterioration, increased non-communicable disease rates, lost productivity and quality of life, and increased medical costs. While adequate nutrition is fundamental to good health, it remains unclear what impact various dietary interventions may have on improving healthspan and quality of life with age. With a rapidly ageing global population, there is an urgent need for innovative approaches to health promotion as individual’s age. Successful research, education, and interventions should include the development of both qualitative and quantitative biomarkers and other tools which can measure improvements in physiological integrity throughout life. Data-driven health policy shifts should be aimed at reducing the socio-economic inequalities that lead to premature ageing. A framework for progress has been proposed and published by the World Health Organization in its Global Strategy and Action Plan on Ageing and Health. This symposium focused on the impact of nutrition on this framework, stressing the need to better understand an individual’s balance of intrinsic capacity and functional abilities at various life stages, and the impact this balance has on their mental and physical health in the environments they inhabit.

Apr 13, 2020

Whooping cough resurgence due to vaccinated people not knowing they’re infectious?

Posted by in categories: biotech/medical, health

Whooping cough has made an astonishing comeback, with 2012 seeing nearly 50,000 infections in the U.S. (the most since 1955), and a death rate in infants three times that of the rest of the population. The dramatic resurgence has puzzled public health officials, who have pointed to the waning effectiveness of the current vaccine and growing anti-vaccine sentiment as the most likely culprits.

But that might not be the whole story, suggests a new study published in BMC Medicine by Santa Fe Institute Omidyar Fellows Ben Althouse and Sam Scarpino. Their research points to a different, but related, source of the outbreak — vaccinated people who are infectious but who do not display the symptoms of whooping cough, suggesting that the number of people transmitting without symptoms may be many times greater than those transmitting with symptoms.

In the 1950s, highly successful vaccines based on inactivated pertussis cells (the bacteria that causes whooping cough) drove infection rates in the U.S. below one case per 100,000 people. But adverse side effects of those vaccines led to the development and introduction in the 1990s of acellular pertussis vaccines, which use just a handful of the bacteria’s proteins and bypass most of the side effects. (Currently given to children as part of the Tdap vaccine.)