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Archive for the ‘biotech/medical’ category: Page 1653

Apr 17, 2020

Molecular networks serve as cellular blueprints

Posted by in categories: bioengineering, biotech/medical, genetics, health

Networks are at the heart of everything from communications systems to pandemics. Now researchers have found that a unique type of network also underlies the structures of critical cellular compartments known as membraneless organelles. These findings may provide key insights into the role of these structures in both disease and cellular operations.

“Prior to this study, we knew the basic physical principle by which these protein-rich compartments form — they condense from the cytoplasm into liquid droplets like dew on a blade of grass,” said David Sanders, a post-doctoral researcher in Chemical and Biological Engineering at Princeton University. “But unlike dew drops, which are composed of a single component (water), cellular droplets are intimidatingly complex. Our work uncovers surprisingly simple principles that we think are universal to the assembly of liquid organelles, and opens new frontiers into studying their role in health and disease.”

Sanders is the lead author in an article in the journal Cell describing a blueprint for the assembly of these liquid structures, also called condensates. The researchers looked closely at two types of condensates, stress granules and processing bodies (“P-bodies”). In the Cell paper, researchers directed by Clifford Brangwynne, a professor of Chemical and Biological Engineering at Princeton and the Howard Hughes Medical Institute, combined genetic engineering and live cell microscopy approaches to reveal the rules underlying the assembly and structure of stress granules, and why they remain distinct from their close relatives, P-bodies.

Apr 17, 2020

Google will add Zoom-like gallery view to Meet and will let Meet users take calls from Gmail

Posted by in categories: biotech/medical, business, computing, education

Google plans to add a Zoom-like gallery view to its business- and education-focused Meet videoconferencing service and let users start calls and join meetings right from Gmail, Google’s GM and VP of G Suite Javier Soltero told Reuters in an interview. The additions come amid huge growth for Meet as families, students, and workers use the service while at home due to the COVID-19 pandemic.

The upcoming gallery view will let users display up to 16 meeting participants in one frame, according to Reuters. That functionality is coming later this month, said Soltero. Zoom’s gallery view, by contrast, lets you see the thumbnails of up to 49 people in one screen, if you have a powerful enough CPU to display them all.

Apr 17, 2020

UK scientists to make a million potential COVID-19 vaccines before proof

Posted by in category: biotech/medical

LONDON (Reuters) — A million doses of a potential COVID-19 vaccine being developed by British scientists are already being manufactured and will be available by September, even before trials prove whether the shot is effective, the team said on Friday.

Apr 17, 2020

She tested a coronavirus vaccine a month ago. Here’s what the last 4 weeks have been like

Posted by in category: biotech/medical

The Seattle woman was the first to receive this vaccine.

Apr 17, 2020

Coronavirus test using CRISPR detects disease in under 40 minutes

Posted by in category: biotech/medical

The new diagnostic tool, Detectr, shows promise in rapidly detecting COVID-19.

Apr 17, 2020

In the Future, Human Cloning Might Mean Giving Birth to Your Own Sibling

Posted by in categories: biotech/medical, futurism

Human clones have long been a topic of science fiction, but how far off are they in reality? Let’s take a look at current advances and see when and where we might see the first human clone.

Apr 17, 2020

New clues to predict the risks astronauts will face from space radiation on long missions

Posted by in categories: biotech/medical, genetics, health

The National Aeronautics and Space Administration, NASA, aims to send human missions to Mars in the 2030s. But scientists are still trying to learn more about the potential cancer risks for astronauts due to radiation exposure. Cancer risk from galactic cosmic radiation exposure is considered a potential “showstopper” for a manned mission to Mars.

A team led by researchers at Colorado State University used a novel approach to test assumptions in a model used by NASA to predict these . The NASA model predicts that astronauts will have more than a three percent risk of dying of from the exposures they will receive on a Mars mission. That level of risk exceeds what is considered acceptable.

The study, “Genomic mapping in outbred mice reveals overlap in genetic susceptibility for HZE ion- and gamma-ray-induced tumors,” was published April 15 in Science Advances.

Apr 17, 2020

Moscow’s Facial Recognition Tech Will Outlast the Coronavirus

Posted by in categories: biotech/medical, robotics/AI, surveillance

👽 Facial recognition and Covid 19 in Moscow, Russia.

Fyodor R.

Continue reading “Moscow’s Facial Recognition Tech Will Outlast the Coronavirus” »

Apr 17, 2020

What do we know about COVID-19 and sewage?

Posted by in categories: biotech/medical, health, surveillance

A version of this story was first published by COVID-19 Waterblog. Read the original.

There has been quite some talk about SARS-CoV-2 shedding in faeces and what that might mean for the water industry. Here, Susan Petterson provides a snapshot of the current data.

As I see it, there are two aspects to this conversation: the first is a concern that sewage may contain infectious SARS-CoV-2 viruses; and the second relates to the more theoretical potential of using SARS-CoV-2 RNA concentration in sewage as a public health surveillance tool.

Apr 17, 2020

Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

Posted by in category: biotech/medical

Lysergic acid diethylamide (LSD) is a prototypical serotonergic psychedelic drug and the subject of many clinical investigations. In recent years, a range of lysergamides has emerged with the production of some being inspired by the existing scientific literature. Others, for example various 1-acyl substituted lysergamides, did not exist before their appearance as research chemicals. 1-Cylopropanoyl-LSD (1CP-LSD) has recently emerged as a new addition to the group of lysergamide-based designer drugs and is believed to be psychoactive in humans. In this investigation, 1CP-LSD was subjected to detailed analytical characterizations including various mass spectrometry (MS) platforms, gas and liquid chromatography, nuclear magnetic resonance spectroscopy, solid phase and GC condensed phase infrared spectroscopy. Analysis by GC-MS also revealed the detection of artificially induced degradation products. Incubation of 1CP-LSD with human serum led to the formation of LSD, indicating that it may act as a prodrug for LSD in vivo, similar to other 1-acyl substituted lysergamides. The analysis of blotters and pellets is also included. 1CP-LSD also induces the head-twitch response (HTR) in C57BL/6J mice, indicating that it produces an LSD-like behavioural profile. 1CP-LSD induced the HTR with an ED50 = 430.0 nmol/kg which was comparable with 1P-LSD (ED50 = 349.6 nmol/kg) investigated previously. Clinical studies are required to determine the potency and profile of effects produced by 1CP-LSD in humans.

This article is protected by copyright. All rights reserved.

PMID: 32180350 DOI: 10.1002/dta.