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Molecular Machines: Bacteria-Killing Drills Get an Upgrade

Molecular machines that kill infectious bacteria have been taught to see their mission in a new light.

New nanoscale drills have been developed that are effective at killing bacteria. These novel molecular machines are activated by visible light and can punch holes through the cell membranes of bacteria in just two minutes. As bacteria have no natural defenses against this mechanism, it could be a useful strategy to treat antibiotic-resistant bacteria.

The latest iteration of nanoscale drills developed at Rice University are activated by visible light rather than ultraviolet (UV), as in earlier versions. These have also proven effective at killing bacteria through tests on real infections.

Russian Scientists Synthesize a New Ultra-Hard Material

Russian scientists have synthesized a new ultra-hard material containing scandium and carbon. It consists of polymerized fullerene molecules with scandium and carbon atoms inside. The work paves the way for future studies of fullerene-based ultra-hard materials, making them a potential candidate for use in photovoltaic and optical devices, elements of nanoelectronics and optoelectronics, biomedical engineering as high-performance contrast agents, etc. The research study was published in the journal Carbon.

The discovery of new, all-carbon molecules known as fullerenes almost forty years ago was a revolutionary breakthrough that paved the way for fullerene nanotechnology. Fullerenes have a spherical shape made of pentagons and hexagons that resembles a soccer ball, and a cavity within the carbon frame of fullerene molecules can accommodate a variety of atoms.

Researchers discover brain pathway that helps to explain light’s effect on mood

From changes in daylight across seasons to the artificial lighting choices in workplaces, it’s clear that the quantity and quality of light that a person encounters can significantly impact mood.

Now, scientists at Brown University think they know why.

In a new study published in the Proceedings of the National Academy of Science, the research team used functional MRI to reveal how signals reach the , and how brain structures involved in mood process those signals. The study demonstrated that some regions of the cerebral cortex involved in cognitive processing and mood show sensitivity for intensity.

Discovery of DNA

This video explains discovery of DNA.

DNA was discovered in 1,869 by German researcher Friedrich Miescher, who was originally trying to study the composition of lymphoid cells (white blood cells). Instead, he isolated a new molecule he called nuclein (DNA with associated proteins) from a cell nucleus.

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Scientists Have Created Worms That Can Kill Cancer Cells

Osaka University researchers discovered that worms may be coated with hydrogel sheaths that contain useful cargo such as anti-cancer medications

James Bond’s famed quartermaster Q provided the secret agent with an unlimited supply of equipment and gadgets to aid him on his missions. Now, scientists from Japan have shown that they are equally adept in providing microscopic worms with a surprising variety of useful and protective components.

Researchers from Osaka University have discovered that microscopic, free-living worms known as nematodes may be coated with hydrogel-based “sheaths” that can be further customized to transport functional cargo.

ABSTRACT: @Nicholiscience

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The Neuro-Network.

#Fetal #Brain begin to #experience #pain #neuroscience #science #Biology #consciousness


Context Proposed federal legislation would require physicians to inform women seeking abortions at 20 or more weeks after fertilization that the fetus feels pain and to offer anesthesia administered directly to the fetus. This article examines whether a fetus feels pain and if so, whether safe and effective techniques exist for providing direct fetal anesthesia or analgesia in the context of therapeutic procedures or abortion.

Evidence Acquisition Systematic search of PubMed for English-language articles focusing on human studies related to fetal pain, anesthesia, and analgesia. Included articles studied fetuses of less than 30 weeks’ gestational age or specifically addressed fetal pain perception or nociception. Articles were reviewed for additional references. The search was performed without date limitations and was current as of June 6, 2005.

Evidence Synthesis Pain perception requires conscious recognition or awareness of a noxious stimulus. Neither withdrawal reflexes nor hormonal stress responses to invasive procedures prove the existence of fetal pain, because they can be elicited by nonpainful stimuli and occur without conscious cortical processing. Fetal awareness of noxious stimuli requires functional thalamocortical connections. Thalamocortical fibers begin appearing between 23 to 30 weeks’ gestational age, while electroencephalography suggests the capacity for functional pain perception in preterm neonates probably does not exist before 29 or 30 weeks. For fetal surgery, women may receive general anesthesia and/or analgesics intended for placental transfer, and parenteral opioids may be administered to the fetus under direct or sonographic visualization.

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