Proteins are the building blocks of life, involved in virtually every biological process. Understanding how proteins interact with each other is crucial for deciphering the complexities of cellular functions, and has significant implications for drug development and the treatment of diseases.
Many people are familiar with oncogenes—genes long known to be involved in cancers in humans, such as the gene Src. What’s less widely understood is that oncogenes didn’t evolve just to cause cancer in species, but rather to control events of normal growth and differentiation.
To help myself and others keep track of the fast-paced world of biotech, I have put together this list of 107 companies and notable research nonprofits! I wrote down some important facts about each entry as well as included links to their websites.
PDF version: List of Biotechnology Companies to Watch – by Logan Thrasher Collins
I created this list of organizations (107 total to date) to serve as a resource to help people learn about and keep track of key biotechnology companies. Some of these are emerging startups, some are established giants, and some provide useful services. Some notable nonprofit organizations are included as well. Though this list is far from comprehensive, I have tried to cover as many of the key players as possible. It is also important to realize that this landscape is constantly changing, so some of the information on this list will eventually transition into antiquity. The list was originally started over the course of 2021, updated during the summer of 2022, and updated again during the summer of 2024. I hope you enjoy delving into the exciting world of biotechnology!
A UK teenager with severe epilepsy has become the first person in the world to be fitted with a brain implant aimed at bringing seizures under control.
Oran Knowlson’s neurostimulator sits under the skull and sends electrical signals deep into the brain, reducing his daytime seizures by 80%.
His…
Continue reading “UK boy has brain implant fitted to control epilepsy seizures in world first” »
Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer’s and similar diseases, before extensive brain cell death and dementia set in. A study published in Alzheimer’s & Dementia shows up to a six-month window in which disease progress could be tracked and treatments tested in rhesus macaques.
Chinese scientists have engineered a solution by which they could bypass natural plant gene inheritance. They aim to deploy a CRISPR-based gene editing system to help the transmission of preferred genes even when they aren’t suitable for a plant.
The scientists devised a system that would use both a toxin and an antidote which would directly affect the male plant germline. Through this process, the researchers could overcome the natural Mendelian transmission rate. This can help increase the gene transmission rates up to 99% over two generations.
This study identifies a small molecule (TAC) that restores physiological levels of TERT throughout aged tissues, resulting in the rejuvenation of multiple tissues. Specifically, TAC administration in very aged mice alleviates multiple aging hallmarks such as cellular senescence and systemic inflammation, promotes new neuron formation with improved cognitive ability, enhances neuromuscular function, and is well tolerated with no evidence of toxicity.
Successful immune defense requires activation, regulation, and resolution of the immune response. Save this comprehensive reference on the cellular components of the immune system.
A little scifi sold again as near future situation.
Introducing Cognify, the prison of the future. This facility is designed to treat criminals like patients. Instead of spending years in an actual prison cell, prisoners could finish their sentence here in just a few minutes. Cognify could someday create and implant artificial memories directly into the prisoner’s brain. It could offer a new approach to criminal rehabilitation, transforming how society deals with offenders by focusing on rehabilitation rather than punishment. #Science #Technology #Research #NeuroScience #psychology.
Menthol detection predates the sensation of cold, indicating separate activation mechanisms that can be distinguished. This differentiation opens possibilities for novel pain treatments that avoid unwanted thermal side effects.
Millions of people around the globe suffer from chronic pain, and many existing treatments depend on opioids, which have significant addiction and overdose risks. Developing non-addictive pain relief options could transform how pain is managed. Recent research focusing on a human protein that controls cold sensations are paving the way for new pain medications. These innovative drugs aim to manage pain without altering body temperature or posing addiction risks.
A new study published in Science Advances on June 21, led by Wade Van Horn, professor in Arizona State University’s School of Molecular Sciences and Biodesign Center for Personalized Diagnostics, has uncovered new insights into the main human cold and menthol sensor TRPM8 (transient receptor potential melastatin 8). Using techniques from many fields like biochemistry and biophysics, their study revealed that it was a chemical sensor before it became a cold temperature sensor.
