The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 cancer whole genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.
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O’Neill Cylinders space stations are examples of large rotating habitats able to be constructed in space in which people and even a complex ecology might be transplanted. But what would it be like living in one and how would civilizations based inside them in the future tend to operate?
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https://www.youtube.com/watch?v=DXo5BVdzZQE
Ira Pastor, ideaXme exponential health ambassador interviews Dr. Tara O’Toole, Executive Vice President and Senior Fellow at In-Q-Tel.
https://www.cia.gov/library/publications/intelligence-history/in-q-tel
Continue reading “Dr Tara O’Toole: The CIA, National Security And Preventing The Next Pandemic” »
Doctor-who-alerted-world-to-wuhan-coronavirus-tragically-succumbed-to-the-virus.
A Chinese doctor, among the first to raise the alert about China’s new coronavirus, himself died from the pathogen on Friday, emphasizing the depth of a worsening crisis that has killed more than 560 people.
Global panic also spread, with thousands trapped on quarantined cruise ships.
Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn’t a particularly good birthday present. (Wow, what’d I get this year? Just what I didn’t want: sarcopenia and hearing loss!)
Given the downsides of aging, it really is surprising how little people talk about it beyond the odd grumble or even as a joke. Normally, it’s to complain about the aches and pains that gradually appear as the years roll by, as we find it harder to walk up the stairs and “bright-eyed and bushy-tailed” turns into “cloudy-eyed and with an aching back”.
That’s not even the serious side of aging, which involves the gradual loss of independence and the age-related diseases that first rob us of our quality of life before they get around to killing us. The serious part is the horror of Alzheimer’s and the loss of self that it brings, the heart disease that cripples us, the frailty that steals our independence, and the lurking threat of cancer that rises dramatically as we age.
Coronavirus-cure-indian-scientists-team-is-very-close-to-developing-vaccine-for-coronavirus.
In a major breakthrough that can lead to a quick Coronavirus vaccine, a team of scientists led by an overseas citizen of India, Professor SS Vasan of CSIRO (Commonwealth Scientific and Industrial Research Organization) Dangerous Pathogens Team has successfully mass produced the novel Coronavirus strain outside China in sufficiently large number to begin clinical trial of medicine.
#survival #coronavirus
In light of recent events its a good opportunity to go over the basics of pandemic preparedness.
*Correction* I need to make a correction to information provided within this video. The case-fatality rate of the Spanish influenza is often quoted by virologists as 2.5 % when in reality the math on this doesn’t add up as the population of the planet at the time doesn’t align with this statistic. This stat is misinterpreted to mean the overall case-fatality rate was (greater than) 2.5%. It is presumed a safer mortality estimate was between 7.5%-15% at the pandemics peak wave. The correct statistic is the 2.5%-5% of the WORLDS population perished as a result of this. It should be noted that there were several waves to this pandemic hence the 2.5 (greater than) statistic. The first wave was relatively tame, the second wave was devastating, the third wave was less severe. https://www.cdc.gov/flu/pandemic-resources/1918-commemoration/three-waves.htm
Continue reading “10 Steps to Survive a Global Pandemic: Coronavirus” »
Front Microbiol. 2018 Sep 27;9:2338. doi: 10.3389/fmicb.2018.02338. eCollection 2018.
Influenza A virus causes periodic outbreaks and seriously threatens human health. The drug-resistant mutants have shown an epidemic trend because of the abuse of chemical drugs. Aloe polysaccharides (APS) extracted from Aloe vera leaves have evident effects on the therapy of virus infection. However, the activity of APS in anti-influenza virus has yet to be investigated. Here, we refined polysaccharides from A. vera leaf. In vitro test revealed that APS could inhibit the replication of a H1N1 subtype influenza virus, and the most obvious inhibitory effect was observed in the viral adsorption period. Transmission electron microscopy indicated that APS directly interacted with influenza virus particles. Experiments on PR8 (H1N1) virus infection in mice demonstrated that APS considerably ameliorated the clinical symptoms and the lung damage of the infected mice, and significantly reduced the virus loads and mortality.
