Lifeboat Foundation

Two studies find strong predictive power of microbiome in complex diseases and death.

“Unprecedented results” showed that longer than normal telomeres in mice hahd only beneficial effects, such as increased longevity, delayed metabolic age and fewer cancers.

The Měnglà virus can infect human cells but the risk of its transmission from bats to humans is unknown.

Zheng-Li Shi at the Chinese Academy of Sciences in Wuhan and their colleagues examined a Rousettus fruit bat caught in southern China. The bat’s liver contained a new type of filovirus that the researchers named Měnglà virus for the county where the bat was captured. Měnglà is substantially different from both Ebola and Marburg virus, highlighting the genetic diversity of filoviruses in bats.

Zoonotic diseases may become the source of more outbreaks in the future. People must take note and pass the appropriate regulations to prevent future outbreaks.

https://www.newsroom.co.nz/2020/01/22/996315/are-bats-to-blame-for-chinas-virus#

As bats and humans cross paths more viruses are making the jump from bat to people. China’s latest scare is the latest coronavirus to affect humans likely to have its origins in bats.

Continue reading “Are bats to blame for China’s virus?” »

https://news.wisc.edu/study-reveals-interplay-of-an-african-…d-a-virus/

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrom Coronavirus (MERS-CoV) it has become increasingly clear that bats are important reservoirs of CoVs. Despite this, only 6% of all CoV sequences in GenBank are from bats. The remaining 94% largely consist of known pathogens of public health or agricultural significance, indicating that current research effort is heavily biased towards describing known diseases rather than the ‘pre-emergent’ diversity in bats. Our study addresses this critical gap, and focuses on resource poor countries where the risk of zoonotic emergence is believed to be highest. We surveyed the diversity of CoVs in multiple host taxa from twenty countries to explore the factors driving viral diversity at a global scale. We identified sequences representing 100 discrete phylogenetic clusters, ninety-one of which were found in bats, and used ecological and epidemiologic analyses to show that patterns of CoV diversity correlate with those of bat diversity. This cements bats as the major evolutionary reservoirs and ecological drivers of CoV diversity. Co-phylogenetic reconciliation analysis was also used to show that host switching has contributed to CoV evolution, and a preliminary analysis suggests that regional variation exists in the dynamics of this process. Overall our study represents a model for exploring global viral diversity and advances our fundamental understanding of CoV biodiversity and the potential risk factors associated with zoonotic emergence.

Scientists have been able to capture real-time 3D footage of blood flowing through the human body, which could help doctors observe the function of multiple organs at the same time.

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A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality.

Rather than directions going one-way from DNA to RNA to proteins, the latest study shows that RNA itself modulates how DNA is transcribed—using a chemical process that is increasingly apparent to be vital to biology. The discovery has significant implications for our understanding of human disease and drug design.

“It appears to be a fundamental pathway we didn’t know about. Anytime that happens, it holds promise to open up completely new directions of research and inquiry,” said Prof. Chuan He, a world-renowned chemist.

Human skin is a fascinating multifunctional organ with unique properties originating from its flexible and compliant nature. It allows for interfacing with external physical environment through numerous receptors interconnected with the nervous system. Scientists have been trying to transfer these features to artificial skin for a long time, aiming at robotic applications.

Robotic systems heavily rely on electronic and magnetic field sensing functionalities required for positioning and orientation in space. Much research has been devoted to implementation of these functionalities in a flexible, compliant form. Recent advancements in flexible sensors and organic electronics have provided important prerequisites. These devices can operate on soft and elastic surfaces, whereas sensors perceive various physical properties and transmit them via readout circuits.

To closely replicate natural skin, it is necessary to interconnect a large number of individual sensors. This challenging task became a major obstacle in realizing electronic skin. First demonstrations were based on an array of individual sensors addressed separately, which unavoidably resulted in a tremendous number of electronic connections. In order to reduce the necessary wiring, important technology had to be developed—namely, complex electronic circuits, current sources and switches had to be combined with individual magnetic sensors to achieve fully integrated devices.