Lifeboat Foundation

Hallucinations are spooky and, fortunately, fairly rare. But, a new study suggests, the real question isn’t so much why some people occasionally experience them. It’s why all of us aren’t hallucinating all the time.

In the study, Stanford University School of Medicine neuroscientists stimulated nerve cells in the visual cortex of mice to induce an illusory image in the animals’ minds. The scientists needed to stimulate a surprisingly small number of nerve cells, or neurons, in order to generate the perception, which caused the mice to behave in a particular way.

“Back in 2012, we had described the ability to control the activity of individually selected neurons in an awake, alert animal,” said Karl Deisseroth, MD, Ph.D., professor of bioengineering and of psychiatry and behavioral sciences. “Now, for the first time, we’ve been able to advance this capability to control multiple individually specified cells at once, and make an animal perceive something specific that in fact is not really there—and behave accordingly.”

https://www.prweb.com/releases/regenerage_international_iime…449142.htm

In a recent study, a group of researchers from Hebrew University-Hadassah Medical School, Feinberg School of Medicine, and Tel Aviv University examined astrocytes in mice and found that these cells exhibited a senescent phenotype that led to neurodegeneration and neurotoxicity [1].

Age-dependent increase in senescent astrocytes adjacent to Aβ plaques

Cellular senescence, discovered in 1961 by Leonard Hayflick and Paul Moorhead, is a state in which cells no longer perform their functions, instead emitting harmful chemicals that turn other cells senescent… These cells are caused primarily by telomere shortening and DNA damage, they are known to contribute to many diseases, and this is not the first study that links them to neurodegeneration.

The rules about what makes a good magnet may not be as rigid as scientists thought. Using a mixture containing magnetic nanoparticles, researchers have now created liquid droplets that behave like tiny bar magnets.

Magnets that generate persistent magnetic fields typically are composed of solids like iron, where the magnetic poles of densely packed atoms are all locked in the same direction (SN: 2/17/18, p. 18). While some liquids containing magnetic particles can become magnetized when placed in a magnetic field, the magnetic orientations of those free-floating particles tend to get jumbled when the field goes away — causing the liquid to lose its magnetism.

Continue reading “Permanent liquid magnets have now been created in the lab” »

A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors.

Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth. The drug also is lower in toxicity than current chemotherapy drugs, leading to fewer side effects.

“It’s like a Trojan horse,” Northwestern University’s Nathan Gianneschi, who led the research. “It looks like a nice little fatty acid, so the tumor’s receptors see it and invite it in. Then the drug starts getting metabolized and kills the tumor cells.”

Dr. Wim Melis from the University of Greenwich is working on deconstructing and reconstructing audio signals with extremely high accuracy.

Audio is captured and, from there, converted into a spiking signal—the type the brain uses. This is then fed into the brain and reconstructed as a 90–100 percent replica of the original sound.

Current technologies, known as cochlear implants, only achieve a fraction of this. They do the work of damaged parts of the inner ear (cochlea) to provide sound signals to the brain, whereas hearing aids make sounds louder.

Scientists at Berkeley Lab have made a new material that is both liquid and magnetic, opening the door to a new area of science in magnetic soft matter. Their findings could lead to a revolutionary class of printable liquid devices for a variety of applications from artificial cells that deliver targeted cancer therapies to flexible liquid robots that can change their shape to adapt to their surroundings. (Video credit: Marilyn Chung/Berkeley Lab; footage of droplets courtesy of Xubo Liu and Tom Russell/Berkeley Lab)

The three-hour event was part marketing spectacle and part dry technical explainer. Musk and his team members described the brain-machine interface design they’re betting on, which will employ dozens of thin wires to collect signals in the brain, and which they want to try out on paralyzed people soon, so they can type with their minds. Their eventual aim is to connect those wires to a thought transmitter which tucks behind your ear like a hearing aid.

Well, it’s pretty cool. It seemed like maybe it will work the way they want down the road, but it probably doesn’t work that way now. A couple of years ago, when I heard he was working with a neural interface, I said I would be there in a heartbeat. I was joking, but it’s interesting to think about what I am going to do when I get explanted. I am coming up on my five years. Then the FDA says my implants may have to come out. Neuralink talked about longevity of the implant and also a large number of electrodes. I always say I wish they had put more electrodes into me.

Basically, the more electrodes you have, the more neurons you record from, so I would imagine higher-degree tasks would be easier. I am limited to thinking about my right arm and hand. I thought it would be good to have more control. I always want to play more video games.

Continue reading “Man with brain implant on Musk’s Neuralink: ‘I would play video games’” »

Using a new technique, scientists have performed the world’s smallest magnetic resonance imaging to capture the magnetic fields of single atoms. It’s an incredible breakthrough that could improve quantum research, as well as our understanding of the Universe on subatomic scales.

“I am very excited about these results,” said physicist Andreas Heinrich of the Institute for Basic Sciences in Seoul. “It is certainly a milestone in our field and has very promising implications for future research.”

You’re probably most familiar with magnetic resonance imaging, or MRI, as a method used to image internal body structures in medicine. An MRI machine uses highly powerful magnets to induce a strong magnetic field around the body, forcing the spin of the protons in the nuclei of your body’s hydrogen atoms to align with the magnetic field, all without producing side-effects.