Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 1,932

Plasma Dilution Potential Benefits & Real Cases Part III | Dr Dobri Kiprov Interview Series

Interested in living longer? You are probably going to get TPE at some point. The Conboys are looking for funding for human trials to produce a product in 3–4 years. Here we have infor on what it is and how it works plus actual human results to date (starting at 10 minutes).

In Part III, Dr Kiprov, discusses the history of moving from the Conboy’s experiments in the lab to the process used in the clinic and reasons for the choices made. He also covers the benefits that he has seen with plasma exchange in the clinic.

Part I Video Link https://youtu.be/jpJlgSzRdyo.
Part II Video Link https://youtu.be/P0j96lU9_-g.

Dr Dobri Kiprov is internationally recognized as a pioneer and a leading expert in the field of Therapeutic Apheresis. He is Chief of the Division of Immunotherapy at California Pacific Medical Center in San Francisco, California and Medical Director of Apheresis Care Group (ACG).

Dr Kiprov has been working with the Drs Conboy for many years on plasma exchange and recently they published a joint paper based on their experience in the clinic and the laboratory.

Continue reading “Plasma Dilution Potential Benefits & Real Cases Part III | Dr Dobri Kiprov Interview Series” | >

Advanced care: Smart Wound Dressings with Built-in Healing Sensors

Fluorescent sensors glow brightly under UV light if infection starts to set in. Researchers have developed smart wound dressings with built-in nanosensors that glow to alert patients when a wound is not healing properly.

The multifunctional, antimicrobial dressings feature fluorescent sensors that glow brightly under UV light if infection starts to set in and can be used to monitor healing progress.

The smart dressings, developed by a team of scientists and engineers at RMIT University in Melbourne, Australia, harness the powerful antibacterial and antifungal properties of magnesium hydroxide.

Repairing hearts with deadly spider venom

A potentially life-saving treatment for heart attack victims has been discovered from a very unlikely source — the venom of one of the world’s deadliest spiders.

A drug candidate developed from a molecule found in the venom of the Fraser Island (K’gari) funnel web spider can prevent damage caused by a heart attack and extend the life of donor hearts used for organ transplants. The discovery was made by a team led by Dr Nathan Palpant and Professor Glenn King from The University of Queensland (UQ) and Professor Peter Macdonald from the Victor Chang Cardiac Research Institute.

Dr Palpant, from UQ’s Institute for Molecular Bioscience (IMB), said the drug candidate worked by stopping a ‘death signal’ sent from the heart in the wake of an attack.

New artificial intelligence software can compute protein structures in 10 minutes

Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or CASP14, conference. The wait is now over.

Researchers at the Institute for Protein Design at the University of Washington School of Medicine in Seattle have largely recreated the performance achieved by DeepMind on this important task. These results will be published online by the journal Science on Thursday, July 15.

Unlike DeepMind, the UW Medicine team’s method, which they dubbed RoseTTAFold, is freely available. Scientists from around the world are now using it to build models to accelerate their own research. Since July, the program has been downloaded from GitHub by over 140 independent research teams.

DeepMind reveals more about how it cracked protein folding

Today, in a peer-reviewed paper published in the prestigious scientific journal Nature, DeepMind offered further details of how exactly its A.I. software was able to perform so well. It has also open-sourced the code it used to create AlphaFold 2 for other researchers to use.

But it’s still not clear when researchers and drug companies will have easy access to AlphaFold’s structure predictions.

“Neuroprosthesis” Restores Words to Man with Paralysis

Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a screen.

The achievement, which was developed in collaboration with the first participant of a clinical research trial, builds on more than a decade of effort by UCSF neurosurgeon Edward Chang, MD, to develop a technology that allows people with paralysis to communicate even if they are unable to speak on their own. The study appears July 15 in the New England Journal of Medicine.

Newly-Discovered ‘Borg’ DNA Is Unlike Anything Scientists Have Ever Seen

That said, the Borgs do clearly contain metabolic genes, which might be able to boost the energy metabolisms of Methanoperedens that host them. If so, these unique genetic elements could provide new insights into reducing methane emissions, which is a major aim for climate change mitigation plans.

These ‘Borg’ elements assimilated genes from other organisms, and could be used to help fight climate change.

Compound Derived From Turmeric Essential Oil Has Neuroprotective Properties

Summary: Aromatic turmerone, a compound derived from turmeric essential oil, and its derivatives directly affect dopamine neurons to generate neuroprotective properties in tissue culture models of Parkinson’s disease.

Source: Kumamoto University.

Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, aromatic turmerone (ar-turmerone), and its derivatives act directly on dopaminergic nerves to create a neuroprotective effect on tissue cultures of a Parkinson’s disease model.

Mini-Brain Study Shows How Environmental Risk Factors Can Amplify Genetic Risks for Autism

Summary: Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrupt neurodevelopment.

Source: Johns Hopkins University.

Researchers at Johns Hopkins Bloomberg School of Public Health have shown in a brain organoid study that exposure to a common pesticide synergizes with a frequent autism-linked gene mutation.

/* */