Lifeboat Foundation

A transistor, conceived of in digital terms, has two states: on and off, which can represent the 1s and 0s of binary arithmetic.

But in analog terms, the transistor has an infinite number of states, which could, in principle, represent an infinite range of mathematical values. Digital computing, for all its advantages, leaves most of transistors’ informational capacity on the table.

In recent years, analog computers have proven to be much more efficient at simulating biological systems than digital computers. But existing analog computers have to be programmed by hand, a complex process that would be prohibitively time consuming for large-scale simulations.

Power consumption is one of the biggest reasons why you haven’t seen a brain-like computer beyond the lab: the artificial synapses you’d need tend to draw much more power than the real thing. Thankfully, realistic energy use is no longer an unattainable dream. Researchers have built nanowire synapses that consume just 1.23 femtojoules of power — for reference, a real neuron uses 10 femtojoules. They achieve that extremely low demand by using a wrap of two organic materials to release and trap ions, much like real nerve fibers.

There’s a lot of work to be done before this is practical. The scientists want to shrink their nanowires down from 200 nanometers thick to a few dozen, and they’d need new 3D printing techniques to create structures that more closely imitate real brains. Nonetheless, the concept of computers with brain-level complexity is that much more realistic — the team tells Scientific American that it could see applications in everything from smarter robots and self-driving cars through to advanced medical diagnosis.

Metastasis (spread of cancer) is one of the biggest challenges in cancer treatment. It is often not the original tumor that kills, but secondary growths. But a key question in cancer research has been how vulnerable cancer cells are able to survive once they break away from a tumor to spread around the body.

“Metastasis is currently incurable and remains one of the key targets of cancer research,” said lead researcher Stéphanie Kermorgant, PhD, from Barts Cancer Institut at Queen Mary University of London (QMUL). “Our research advances the knowledge of how two key molecules communicate and work together to help cancer cells survive during metastasis. We’re hoping that this might lead to the discovery of new drugs to block the spread of cancer within the body.”

Continue reading “Unexpected discovery reveals secret of how cancer spreads in the body” »

Researchers are building an electronic nose that can accurately detect and distinguish chemicals in your breath, which could lead to earlier diagnosis of diseases and eventually replace blood tests. Beta testing is targeted early in 2018.

My new Psychology Today story on BREXIT and the EU:

Scientific innovation doesn’t just happen on its own. It takes stable economies, free societies, and open-minded governments. The best environment for science to thrive in is that of collaborating groups incentivized to communicate and cooperate with one another. This is precisely what the European Union is.

And now, more than ever, the union of Europe is needed—because we are crossing over into the transhumanist age, where radical science and technology will engulf our lives and challenge our institutions. Robots will take 75% of the jobs in the next 25 years. CRISPR gene editing technology will allow us to augment our intelligence, perhaps doubling our IQ. Bionic organs will stave off death, allowing 200 year lifespans.

Continue reading “Scientific Innovation Needs the European Union to Succeed” »

Excellent!!! Cannot wait until we eradicate cancer, MS, Parkinson, Dystonia, Cystic-Fibrosis, LGD, etc.

A team of Physicians at the University of Pennsylvania’s School of Medicine now has their project of modifying the immune cells of 18 different cancer patients with the CRISPR-Cas9 system approved by the National Institute of Health.

CRISPR is the gift that keeps on giving—when it’s not fighting blindness, tackling HIV, or even recording real-time immune responses, it is taking on the emperor of all maladies: cancer.

Continue reading “Approved: First Ever Human Trials Involving CRISPR Gene Editing” »

3D Printing never ceases to amaze me.

Doctors at Boston Children’s Hospital used a 3D printout of a boy’s skull to prepare for the surgery that saved his life, STAT reports.

Bentley Yoder was born with encephalocele, a rare and often fatal defect in which the skull doesn’t form properly. In Bentley’s case, a significant portion of his brain grew outside of his skull, according to STAT. Despite being told he would not survive, his parents, Dustin and Sierra, continued to seek treatment that would give their son a future, eventually traveling from their home in Ohio to Boston Children’s Hospital.

Continue reading “Boston Children’s Hospital uses 3D printing to help baby born with brain outside his skull” »

Who needs cloning or gene editing; when you have 3D printers.

Although—in the grand scheme of things—3D printing is a relatively new technology in the eyes of humanity, that certainly doesn’t mean that it can’t be used to recreate some of the most ancient artifacts and fossils scattered throughout the Earth. Over the past year, we’ve seen 3D printing technology help recreate the oldest chameleon fossil ever found, as well as a 1220-foot Titanosaur fossil. Even some of the world’s tiniest fossils have been digitally resized and 3D printed so that a paleontologist from the University of Oxford could better examine them. Now, trilobites, which are a group of extinct marine arthropods, are undergoing their own unique form of 3D printed treatment.

Dr. Gianpaolo Di Silvestro, established paleontologist and CEO of the Italian company Trilobite Design Italia, specializes in this group of extinct arthropods, and uses his company to sell both original trilobite fossils and model replicas to collectors, institutions, and museums across the globe. After realizing that a great number of museums were able to provide text information on these fossils, but not a true physical representation, Dr. Di Silvestro decided to provide these museums with palpable trilobite models that would allow visitors to actually hold the ancient past in the palms of their hands. Since traditional fossil casting and modeling proved to be much too costly and time-consuming, Dr. Di Silvestro instead collaborated with Italian architect and 3D designer Francesco Baldassare to work in tandem and design accurate 3D models of trilobites.

Continue reading “Italian Paleontologist Turns to Materialise to Help 3D Print Trilobite Fossils” »

Scientists are one step closer to using CRISPR gene editing on humans, with a US federal advisory panel approving the use of the technique for a study led by the University of Pennsylvania.

The scientists are seeking to use the CRISPR-Cas9 technique to create genetically altered T cells – white blood cells that play an important role in our immune system – that are more effective at fighting cancer cells in patients with melanoma, multiple myeloma, and sarcoma.

“Our preliminary data suggests that we could improve the efficacy of these T cells if we use CRISPR,” lead researcher Carl June told the National Institute of Health’s (NIH) Recombinant DNA Advisory Committee (RAC) on Tuesday.

Continue reading “A federal panel just gave the green light to use gene editing on humans” »