Lifeboat Foundation

Excellent news; Intellia to continue their focus of leveraging the CRISPR/Cas9 across a variety of immune cells, such as natural killer cells and T-cells. From my own experiences with T-cells and other blood disorders; this is a big deal and one that I personally excited to see what potential cures and improvements come about.

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Intellia Therapeutics, a leading gene-editing company, has launched a new division, eXtellia Therapeutics, with the intent of focusing resources and research on ex vivo applications of the novel technology, CRISPR/Cas9. As in vivo and ex vivo programs require different competencies in research, manufacturing and commercialization, eXtellia Therapeutics is being launched to accelerate Intellia’s efforts in areas of significant unmet medical need – immuno-oncology, autoimmune and inflammatory diseases – using an ex vivo approach. Intellia will continue its in vivo programs and strategy through a dedicated scientific team.

“We are excited to announce the establishment of eXtellia, increasing our footprint in ex vivo gene editing for oncology and autoimmune diseases,” said Nessan Bermingham, Ph.D., Chief Executive Officer and Founder, Intellia Therapeutics. “eXtellia enables us to bring together the required capabilities needed to take the CRISPR/Cas9 technology beyond Intellia’s emerging in vivo, HSC and CAR-T efforts. We believe eXtellia further positions us to maximize the CRISPR/ Cas9 opportunity to address severe unmet medical needs for patients.”

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This is excellent news for Epilepsy.

Epilepsy, a disorder in which nerve cell activity in the brain is disturbed, causing seizures, is the fourth most common neurological problem, following only migraine, stroke and Alzheimer’s. There is no cure for epilepsy, but there are a variety of treatment options. The disease is estimated to affect 2.2 million people in the U.S., with 150,000 people developing the condition each year.

Personalized medicine Scientists at AES discussed how new technologies, such as gene editing using CRISPR-Cas9, and next-generation sequencing, are empowering them to take a new crack at the human genome and find new ways to diagnose and treat epilepsy.

Continue reading “Genomics, Cannabidiols Drive Epilepsy Research” »

Tardigrades, or “water bears,” are renowned for their remarkable survival skills. But these microscopic creatures are far more indestructible than we thought. In a recent experiment, scientists in Japan successfully revived a tardigrade that had been frozen for more than three decades.

That’s a new record.

Tardigrades are tiny water-dwelling extremophiles that are capable of withstanding some of the most severe environmental conditions, including freezing, total dehydration, radiation, and even the vacuum of space. Much of this has to do with their extraordinary genome, of which nearly 18% is comprised of DNA from other organisms, including plants, fungi, bacteria, and viruses.

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Scientists have developed motorised ‘spermbots’ by attaching tiny metal helices to sperm cells that can aid poor swimmers to reach an egg, an advance that could improve fertility treatments.

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Was hit by a car when I was younger and broke my leg. This would have been better then a metal rod. Fascinating.

A team of researchers from the University of Michigan has developed a new technique to aid bone repair, using polymer nano-shells to deliver microRNA molecules. The method could one day have a big impact on regenerative medicine, directing cells already present at injury sites to aid healing.

The new study builds on previous research conducted back in 2011, where nanofiber microspheres were used to carry cells to injury sites to help the wounding process. The new work uses the same idea, but rather than transporting foreign cells, focuses on making better use of the cells already at the wound site.

Continue reading “Scientists use polymer nano-shell treatment to order bones to repair themselves” »

I was shocked to learn recently that one of the major reasons longevity drugs haven’t been going to human trials, despite obvious promise, is that the FDA requires that any potential drug trial has to have a disease or condition it treats. Because aging hasn’t been seen as a disease or medical condition, no drug trials have been allowed to go forward to treat it. NONE! Finally, late last year, aging has been OFFICIALLY recognized as a disease and is therefor now a valid target disease for drug trials. **sigh**.

Are we one step closer to developing compounds that can extend our lifespan?

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Interesting and could change as well as acellerate our efforts around bot technology and humans as well as other areas of robotic technology.

Like Jedi Knights, researchers at Purdue University are using the force — force fields, that is. (Photo : Windell Oskay | Flickr)

Continue reading “Watch Scientists Make These Microbots Move With A Magnetic Force Field” »

Wow!!! Chewing gum wearable technology, Cyborg Chips, Ingestible sensors to let doctors know if you’re taking your meds, etc. 2016 is going to be interesting

The phrase “Brave New World” has become one of the most often used clichés in medical technology in recent years. Google the title of Aldous Huxley’s 1932 dystopian, and anticipatory, novel with the word medicine and 2,940,000 results appear.

But could there be better shorthand to describe some of the recent developments in medical, health and bio-tech? Consider these possibilities coming to fruition, or close to, in 2016:

Continue reading “7 Mind-Blowing Digital Health Tools That Could Disrupt Health Care in 2016” »

Researchers in Germany have successfully grown the innermost layer of human fallopian tubes in the lab — the first step towards creating a functional model that will allow scientists to study how reproductive diseases such as cancer start, as well as provide important insight into the enigmatic organs.

The fallopian tubes play a crucial role in the female reproductive system by connecting the ovaries to the uterus, but recent research has suggested that if fallopian tube cells become infected, they can migrate, and could be a key trigger for ovarian cancer — one of the most deadly types of female reproductive cancer.

Despite the importance of these organs, we have a lot to learn about how they function, particularly on the inside — an area that (as you can imagine) is particularly challenging for scientists to study while their patients are alive.

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