Lifeboat Foundation

Researchers from the Institute of General Physics of the Russian Academy of Sciences, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences and MIPT have made an important step towards creating medical nanorobots. They discovered a way of enabling nano- and microparticles to produce logical calculations using a variety of biochemical reactions.

Details of their research project are given in the journal Nature Nanotechnology. It is the first experimental publication by an exclusively Russian team in one of the most cited scientific magazines in many years.

The paper draws on the idea of computing using biomolecules. In electronic circuits, for instance, logical connectives use current or voltage (if there is voltage, the result is 1, if there is none, it’s 0). In biochemical systems, the result can a given substance.

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A sequel to Steven Spielberg’s epic movie, MINORITY REPORT is set in Washington, D.C., 10 years after the demise of Precrime, a law enforcement agency tasked with identifying and eliminating criminals … before their crimes were committed. Now, in 2065, crime-solving is different, and justice leans more on sophisticated and trusted technology than on the instincts of the precogs. Sept. 21 series premiere Mondays 9/8:00c

LIMITLESS, based on the feature film, is a fast-paced drama about Brian Finch, who discovers the brain-boosting power of the mysterious drug NZT and is coerced by the FBI into using his extraordinary cognitive abilities to solve complex cases for them. Sept. 22 series premiere Tuesdays 10/9c

Topics: Cognitive Science/Neuroscience | Entertainment/New Media | Human Enhancement | VR/Augmented Reality/Computer Graphics.

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Human embryos are at the center of a debate over the ethics of gene editing (credit: Dr. Yorgos Nikas/SPL)

The first application to pursue CRISPR/Cas9 genome-editing research in viable human embryos has been submitted to the UK’s fertility regulator by a team of researchers affiliated with the Francis Crick Institute in London.

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Imagine a “smart pill” that can sense problems in your intestines and actively release the appropriate drugs. We have the biological understanding to create such a device, but we’re still searching for electronic materials (like batteries and circuits) that pose no risk if they get stuck in our bodies. In Trends in Biotechnology on September 21, Christopher Bettinger of Carnegie Mellon University presents a vision for creating safe, consumable electronics, such as those powered by the charged ions within our digestive tracts.

Edible electronic medical devices are not a new idea. Since the 1970s, researchers have been asking people to swallow prototypes that measure temperature and other biomarkers. Currently, there are ingestible cameras for gastrointestinal surgeries as well as sensors attached to medications used to study how drugs are broken down in the body.

“The primary risk is the intrinsic toxicity of these materials, for example, if the battery gets mechanically lodged in the gastrointestinal tract–but that’s a known risk. In fact, there is very little unknown risk in these kinds of devices,” says Bettinger, a professor in materials science and engineering. “The breakfast you ate this morning is only in your GI tract for about 20 hours–all you need is a battery that can do its job for 20 hours and then, if anything happens, it can just degrade away.”

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Researchers in Australia have developed a patch lined with microscopic needles that can quickly and painlessly detect disease-carrying proteins in the blood, potentially replacing the need for needle-based blood samples, and time spent waiting for lab analysis.

Based on a similar patch that could one day deliver injection-free vaccines through the skin, the diagnostic nanopatch has been designed to identify diseases such as malaria and dengue fever, which are prevalent in remote areas and developing regions where people might not have the resources to routinely draw blood and analyse it.

“The concept here is that we could just put a patch on the skin and this could give a result based on what it can find in your blood,” one of the researchers, Simon Corrie from the University of Queensland, told Fairfax Media. “The microneedle arrays can capture proteins that circulate around the body that are normally tested for in blood samples.”

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From helicopters to medical devices and power stations, mathematical proof that software at the heart of an operating system is secure could keep hackers out.

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Following the FDA’s recent approval, human trials are expected to begin by the end of the year.

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DNA has garnered attention for its potential as a programmable material platform that could spawn entire new and revolutionary nanodevices in computer science, microscopy, biology, and more. Researchers have been working to master the ability to coax DNA molecules to self assemble into the precise shapes and sizes needed in order to fully realize these nanotechnology dreams.

For the last 20 years, scientists have tried to design large DNA crystals with precisely prescribed depth and complex features – a design quest just fulfilled by a team at Harvard’s Wyss Institute for Biologically Inspired Engineering. The team built 32 DNA crystals with precisely-defined depth and an assortment of sophisticated three-dimensional (3D) features, an advance reported in Nature Chemistry.

The team used their “DNA-brick self-assembly” method, which was first unveiled in a 2012 Science publication when they created more than 100 3D complex nanostructures about the size of viruses. The newly-achieved periodic crystal structures are more than 1000 times larger than those discrete DNA brick structures, sizing up closer to a speck of dust, which is actually quite large in the world of DNA nanotechnology.

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(Phys.org) —Scientists at the University of Bristol have developed a process where reagents are added to a growing carbon chain with extraordinary high fidelity and precise orientation, thereby controlling the conformation of the molecule so that it adopts a helical or linear shape. The process can be likened to a molecular assembly line.

Nature has evolved highly sophisticated machinery for organic synthesis. One of the most beautiful examples is its machinery for the synthesis of polyketides, a very important class of molecules due to their broad spectrum of biological activities (for example antibiotic, antitumor, antifungal, antiparasitic).

Continue reading “Chemists create ‘assembly-line’ for organic molecules” »