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The body’s branching network of peripheral nerves connects neurons in the brain and spinal cord to organs, skin, and muscles, regulating a host of biological functions from digestion to sensation to locomotion. But the peripheral nervous system can do even more than that, which is why DARPA already has research programs underway to harness it for a number of functions—as a substitute for drugs to treat diseases and accelerate healing, for example, as well as to control advanced prosthetic limbs and restore tactile sensation to their users.

Now, pushing those limits further, DARPA aims to enlist the body’s peripheral nerves to achieve something that has long been considered the brain’s domain alone: facilitating learning. The effort will turn on its head the usual notion that the brain tells the peripheral nervous system what to do.

The new program, Targeted Neuroplasticity Training (TNT), seeks to advance the pace and effectiveness of a specific kind of learning—cognitive skills training—through the precise activation of peripheral nerves that can in turn promote and strengthen neuronal connections in the brain. TNT will pursue development of a platform technology to enhance learning of a wide range of cognitive skills, with a goal of reducing the cost and duration of the Defense Department’s extensive training regimen, while improving outcomes. If successful, TNT could accelerate learning and reduce the time needed to train foreign language specialists, intelligence analysts, cryptographers, and others.

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On track to resolving defective RNA through CRISPR-Cas9.


According to a study published in journal Cell on March 17, researchers at University of California, San Diego School of Medicine, have found a way to track RNA in living cells. CRISPR-Cas9, a DNA-editing technique will be applied to target RNA in order to find cure for presently untreatable diseases such as cancer and autism.

There are many diseases that are associated with RNA behavior, which carries the genetic code from the cell’s nucleus. There was no technique found until now that could track RNA in living cells efficiently. However now, CRISPR-Cas9, which so far was only able to manipulate DNA, would now target RNA, which is also called RNA-targeted Cas9.

“Our current work focuses on tracking the movement of RNA inside the cell, but future developments could enable researchers to measure other RNA features or advance therapeutic approaches to correct disease-causing RNA behaviors”, said senior author Gene Yeo, PhD, associate professor of cellular and molecular medicine.

Microscopic robots, powered by bacterial flagellation, are a curious branch of robotics research, potentially leading to devices that can deliver drugs, perform surgical tasks, and help out with diagnostics. While bacteria has been harnessed in the past to power small devices, having those devices actually navigate to a desired target has been a challenge. At Drexel University researchers are now using electric fields to help their bacterial biobots detect obstacles and float around them on their way to the final destination.

The electric fields don’t actually control the bots, but allow the bots to sense their environment and to move around. The devices are powered by rod-shaped S. marcescens bacteria that are normally negatively charged. The researchers positioned two electric fields orthogonally to each other, creating a grid. Obstacles within the grid slightly affect the fields’ shape, which the robot recognizes and uses to avoid the obstacles.

Here are a couple videos demonstrating the bacterial powered microbot:

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If I am not mistaken she edited The Three Body Problem, she did not write it.


In what seems like a story ripped straight from the pages of an Isaac Asimov novel, a recently deceased Chinese woman named Du Hong just had her brain cryogenically frozen in hopes that, in the future, the technology to bring her back to life will be created. No joke. Hong, a science fiction author herself, paid upwards of $120k to have her brain sent from China to Scottsdale, Arizona to undergo a freezing procedure at the Alcor Life Extension Foundation. Her idea is that while modern tech doesn’t allow for the reanimation of her brain today, inevitable advancements in cryonics will one day bring her back to life.

Before passing away last May from pancreatic cancer, the 61-year-old Du decided she wanted to allow her brain to be the subject of experiments after her death. Though it took some time before the team at Alcor actually conducted the procedure, doctors in Beijing prepped Du’s brain after her official time of death on May 30. Despite the Alcor Life Extension Foundation agreeing to freeze Du’s brain, the organization made it clear that it wouldn’t be the one to actually attempt to bring Du back to life in the future.

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In a controversial move, Kuwait has passed a law making it mandatory for all its 1.3 million citizens and 2.9 million foreign residents to have their DNA entered onto a national database.

Anyone who refuses to submit their DNA for testing risks one year in prison and a fine of up to US$33,000, and those who provide a fake sample can be jailed for seven years.

The decision came after an Islamic State-led suicide bombing in Kuwait City on 26 June, which killed 26 people and wounded 227 more. The government hopes that the new database, which is projected to cost around US$400 million, will make it quicker and easier to make arrests in the future.

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