Fasting in office or starving yourself at work might be a health time bomb. Here’s how to stop it to avoid the risk of heart disease and keep it beating strong.
Category: biotech/medical – Page 33
A dietary supplement may offer a novel way to enhance the effectiveness of CAR T cell therapy, according to a study conducted by researchers at the Perelman School of Medicine and the Abramson Cancer Center at the University of Pennsylvania. Although this method requires validation through clinical trials, early findings—recently presented during a press briefing at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition—suggest a potentially affordable and accessible strategy to improve CAR T cell functionality and cancer-fighting capabilities.
CAR T cell therapy, first developed at Penn Medicine, is a personalized cancer treatment that reprograms a patient’s immune cells to target and destroy cancer cells.
“Thousands of patients with blood cancers have been successfully treated with CAR T cell therapy, but it still doesn’t work for everyone,” said co-lead author Shan Liu, PhD, a postdoctoral fellow who presented the study at ASH. “We took an outside-the-box approach to improve CAR T cell therapy, by targeting T cells through diet rather than further genetic engineering.”
Pig-to-human kidney transplants. A blood test for Alzheimer’s. Birth control without a prescription. These were just a few of the advancements in health and medicine in 2024.
Your body is one of the most complex natural structures ever. Billions of cells are put together in a specific way with the result being you. If you look closely between the cells you’ll find the extracellular matrix, a gel-like environment where cells reside and which helps them to talk to each other. However, when disease strikes, cells and the matrix alike can be irreparably damaged, which could lead to the loss of cell function.
In her Ph. D. research, Maritza Rovers looked at ways to make microgel-based scaffolds for cells, which could be used to support eye cells or even promote nerve growth in spinal cord injuries.
Every person on the planet is made up of billions of cells, which are the building blocks of our bodies. Between these cells lies the so-called extracellular matrix (ECM), a gel-like environment in which cells live out their lives.
A rare genetic variant, APOE3 Christchurch, delays Alzheimer’s onset by years in high-risk individuals, offering insights into disease resilience. This discovery could guide new treatments targeting similar protective pathways for Alzheimer’s prevention and therapy.
Two robots, Levita’s Mars and Da Vinci SP, combined for a groundbreaking prostate removal surgery, advancing precision in minimally invasive care.
We’re way behind several species when it comes to regeneration, and scientists are keen to discover the secrets of these other animals so we can learn from them – including, in a new study, the marine worm Platynereis dumerilii.
These worms are experts in regeneration – they can survive losing a large chunk of their bodies – and now we have a better idea of how they’re doing it: specialized cells near a wound are reverting to their original stem cell-like form, before adapting again to replace lost tissue.
Regeneration in most species is handled by stem cells, which develop into whatever type of cells are needed. However, when the end segment of Platynereis is removed, multiple populations of other cells are recruited to swiftly restore the missing body section.
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An important update on E5.
Here we look at an attempt to replicate the amazing results with E5 from Dr Katcher’s 2020 paper by an institute that has been set up in Brazil.
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Adding a photocopier gene to mRNA vaccines could make them last longer and curb side effects.