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Cognitive neuroscientists discover new blueprint for making and breaking habits

Cognitive neuroscientists at Trinity College Dublin have published new research describing a brand new approach to making habit change achievable and lasting.

This innovative framework has the potential to significantly improve approaches to personal development, as well as the clinical treatment of compulsive disorders (for example , addiction, and eating disorders).

The research was led by Dr. Eike Buabang, Postdoctoral Research Fellow in the lab of Professor Claire Gillan in the School of Psychology, has been published as a paper titled “Leveraging for making and breaking real-world habits” in the journal Trends in Cognitive Sciences.

New method of generating eco-friendly energy uses piezoelectricity

Researchers at University of Limerick in Ireland have developed a new method of growing organic crystals that can be used for energy-harvesting applications.

The energy that is being harvested as part of this research is being generated by squeezing amino acid molecules, the building blocks of proteins that exist in the human body.

Piezoelectricity, which translates from Greek to mean pressing electricity, usually found in ceramics or polymers, is also present in human biomolecules.

Brains Not Required: Cells Exhibit Surprising Learning Abilities

A new study demonstrates that even simple single-cell organisms, such as ciliates and amoebae, exhibit habituation, a basic form of learning previously thought to be exclusive to more complex beings.

This revelation not only changes our understanding of cellular capabilities but also opens up possibilities for applications in cancer immunology, suggesting that our immune cells might be reprogrammed to better recognize and attack cancer cells.

A dog learns to sit on command. A person tunes out the steady hum of a washing machine while engrossed in a book. The ability to learn and adapt is a cornerstone of evolution and survival.

Platelets gliding along surfaces: Using this concept to improve anti-thrombotic treatments

The risk for thrombosis on equipment within coronary arteries during PCI – and the potential dangerous complications – has led to nearly 50 years of targeted research on the mechanisms of normal and pathologic thrombosis. This research has in turn led to the development of blood-thinning drug treatments to prevent thrombosis during and after PCI. However, the blood thinning (‘anti-thrombotic’) therapies can also lead to life-threatening excessive bleeding. Research to identify the optimal balance of anti-thrombotic drugs that minimises both pathologic thrombosis and excessive bleeding continues through today.

Dr Scott Denardo at Duke University Medical Center in the USA has modelled the behaviour of platelets inside blood vessels and near medical device surfaces. Some of his observations are just now entering the contemporary understanding of thrombosis. Denardo believes that applying these observations can refine existing anti-thrombotic therapies to improve their safety (less bleeding) while not compromising their effectiveness (preventing thrombosis on PCI equipment, including stents).

The future of ultrafast electronics

Physicist Matthias Kling studies photons and the things science can do with ultrafast pulses of X-rays. These pulses last just attoseconds – a billionth of a billionth of a second, Kling says. He uses them to create slo-mo “movies” of electrons moving through materials like those used in batteries and solar cells. The gained knowledge could reshape fields like materials science, ultrafast and quantum computers, AI, and medical diagnostics, Kling tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.

Experimental therapeutic reduces advanced-stage influenza viral loads faster than current therapies in preclinical study

Eradivir, a preclinical biotech company, has developed a patent-pending antiviral therapeutic that reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively than currently available therapies.

A single intranasal dose of EV25, a bispecific small molecule developed by Eradivir, acts faster than the current standard of care, eliminating the detectable virus within 24 hours. EV25 also has a window of efficacy of 96 hours postinfection, which is broader than the current standard of care.

A titled “Targeted recruitment of immune effector cells for rapid eradication of infections” has been published in Proceedings of the National Academy of Sciences.

Live Longer, Look Younger: The Groundbreaking Science Of IL-11 Inhibition, 3 Molecules To Reduce It!

Unlock the Secret to a Longer, Healthier Life: The Power of Inhibiting IL-11
Discover the groundbreaking science behind aging in this video, Mr. Bill Faloon presents:
• The Role of IL-11 in Aging: Learn how this inflammatory cytokine accelerates aging and contributes to age-related diseases.
• The Benefits of Inhibiting IL-11: Discover how reducing IL-11 levels can lead to increased lifespan, improved health, and a more youthful appearance.
• Natural Ways to Inhibit IL-11: Learn about dietary supplements and lifestyle habits that can help you lower IL-11 levels.
• The Future of Anti-Aging Medicine: Explore the latest research on drugs and therapies targeting IL-11 and how they may revolutionize the way we approach aging.

https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754292/
Understanding interleukin 11 as a disease gene and therapeutic target.

Blocking Inflammation Protein Extends Lifespan


Blocking Inflammation Protein Extends Lifespan.

https://www.telegraph.co.uk/news/2024/07/17/scientists-find-…op-cancer/

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