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A man paralyzed by a cycling accident is able to walk again after an experimental operation by neuroscientists and surgeons in Switzerland.

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Continue reading “Paralyzed man walks after bluetooth connects his brain and spine” »

How we’re linking together genetic material from thousands of people — modern and ancient — to trace our ancestors and the history of our evolution.

Summary: A novel study uncovers a peculiar pattern of decision-making in mice, influenced by a specific gene named Arc.

While searching for food, mice repeatedly visited an empty location instead of staying at a site abundant in food. However, mice lacking the Arc gene demonstrated a more practical approach, sticking with the food-rich site, thereby consuming more calories overall.

This unique research potentially opens the door for a new field, ‘decision genetics’, investigating the genetic influence on decision-making, possibly even in humans.

In December 2022, founder Elon Musk gave an update on his other, other company, the brain implant startup Neuralink. As early as 2020, the company had been saying it was close to starting clinical trials of the implants, but the December update suggested those were still six months away. This time, it seems that the company was correct, as it now claims that the Food and Drug Administration (FDA) has given its approval for the start of human testing.

Neuralink is not ready to start recruiting test subjects, and there are no details about what the trials will entail. Searching the ClinicalTrials.gov database for “Neuralink” also turns up nothing. Typically, the initial trials are small and focused entirely on safety rather than effectiveness. Given that Neuralink is developing both brain implants and a surgical robot to do the implanting, there will be a lot that needs testing.

It’s likely that these will focus on the implants first, given that other implants have already been tested in humans, whereas an equivalent surgical robot has not.

Learn more about Dr. Hugo De Garis.
https://www.imdb.com/name/nm2433396/

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Continue reading “He Predicted Chat GPT 40 years Ago… Now he Has a Warning” »

Glioblastoma Multiforme (GBM) is the most aggressive and most common primary malignant brain tumor. The age of GBM patients is considered as one of the disease’s negative prognostic factors and the mean age of diagnosis is 62 years. A promising approach to preventing both GBM and aging is to identify new potential therapeutic targets that are associated with both conditions as concurrent drivers. In this work, we present a multi-angled approach of identifying targets, which takes into account not only the disease-related genes but also the ones important in aging. For this purpose, we developed three strategies of target identification using the results of correlation analysis augmented with survival data, differences in expression levels and previously published information of aging-related genes.

A team of engineers at the University of Colorado Boulder has designed a new class of tiny, self-propelled robots that can zip through liquid at incredible speeds—and may one day even deliver prescription drugs to hard-to-reach places inside the human body.

The researchers describe their mini healthcare providers in a paper published last month in the journal Small.

“Imagine if microrobots could perform certain tasks in the body, such as non-invasive surgeries,” said Jin Lee, lead author of the study and a postdoctoral researcher in the Department of Chemical and Biological Engineering. “Instead of cutting into the patient, we can simply introduce the robots to the body through a pill or an injection, and they would perform the procedure themselves.”

Israeli-based health tech company Cordio has developed machine learning software that can be downloaded to a smartphone and help keeps cardiac patients out of the hospital.

One day in the future.

It’s a simple daily habit that could save their life, because one day after repeating their daily refrain, their doctor might be notified that a patient is at risk of heart failure without immediate care.

Continue reading “This AI Startup Aims To Predict Heart Failure Before It Happens” »

The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases like diabetes and cancer.

Traditional synthetic biology approaches for cell-based therapies, such as ones that destroy cancer cells or encourage tissue regeneration after injury, rely on the expression or suppression of proteins that produce a desired action within a cell. This approach can take time (for proteins to be expressed and degrade) and cost cellular energy in the process. A team of Penn State College of Medicine and Huck Institutes of the Life Sciences researchers are taking a different approach.

“We’re engineering proteins that directly produce a desired action,” said Nikolay Dokholyan, G. Thomas Passananti Professor and vice chair for research in the Department of Pharmacology. “Our protein-based devices or nano-computing agents respond directly to stimuli (inputs) and then produce a desired action (outputs).”