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Archive for the ‘biotech/medical’ category: Page 609

Apr 26, 2023

New therapies offer hope for patients with rare genetic conditions

Posted by in categories: biotech/medical, genetics

Genetic conditions like Dravet syndrome are hard to tackle with traditional gene therapy. But new approaches are in the works.

Apr 26, 2023

Alzheimer’s Proteins Reduced by Sleep Drug

Posted by in categories: biotech/medical, neuroscience

Suvorexant (Belsomra), a dual orexin receptor antagonist approved for insomnia, reduced levels of tau phosphorylation and amyloid beta, a small clinical trialopens in a new tab or window showed.

The ratio of phosphorylated tau-threonine-181 (p-tau-181) to unphosphorylated tau-threonine-181 decreased 10% to 15% in cognitively normal adults treated with suvorexant 20 mg compared with placebo, reported Brendan Lucey, MD, MSCI, of Washington University School of Medicine in St. Louis, and co-authors.

Amyloid-beta levels fell 10% to 20% compared with placebo starting 5 hours after suvorexant administration, the researchers wrote in Annals of Neurologyopens in a new tab or window.

Continue reading “Alzheimer’s Proteins Reduced by Sleep Drug” »

Apr 26, 2023

Warning: Common Synthetic Chemicals Disrupt Key Biological Processes — Linked to a Diverse Array of Diseases

Posted by in categories: biotech/medical, chemistry, food, genetics

Researchers from the Keck School of Medicine of USC have discovered that being exposed to a mixture of synthetic chemicals commonly present in the environment affects multiple crucial biological processes in both children and young adults. These processes include the metabolism of fats and amino acids.

<div class=””> <div class=””><br />Amino acids are a set of organic compounds used to build proteins. There are about 500 naturally occurring known amino acids, though only 20 appear in the genetic code. Proteins consist of one or more chains of amino acids called polypeptides. The sequence of the amino acid chain causes the polypeptide to fold into a shape that is biologically active. The amino acid sequences of proteins are encoded in the genes. Nine proteinogenic amino acids are called “essential” for humans because they cannot be produced from other compounds by the human body and so must be taken in as food.<br /></div> </div>

Apr 26, 2023

Neuronal activity shapes the development of astrocytes, shows study

Posted by in categories: biotech/medical, chemistry, neuroscience

Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function. They report in the journal Nature that neuronal activity is necessary and sufficient for astrocytes to develop their complex shape, and interrupting this developmental process results in disrupted brain function.

“Astrocytes play diverse roles that are vital for proper ,” said first author Yi-Ting Cheng, a graduate student in Dr. Benjamin Deneen’s lab at Baylor. “For instance, they support the activity of other essential brain cells, neurons; participate in the formation and function of synapses, or neuron-to-neuron connections; release neurotransmitters, chemicals that mediate neuronal communication; and make the .”

In the adult brain, the bushy shape of is fundamentally linked to effective brain function. The ends of the branched-out astrocyte structure interact with neurons and regulate synaptic activity.

Apr 26, 2023

Unraveling the Genetic Mechanisms Behind Long-Lasting Memories in the Brain

Posted by in categories: biotech/medical, genetics, neuroscience

Summary: Researchers shed new light on the molecular and genetic basis of long-term memory formation in the brain. A new study reveals a single stimulation to the synapses of hippocampal neurons triggered numerous cycles where the memory-coding Arc gene produced mRNA molecules that were then translated into synapse-strengthening Arc proteins. From the findings, researchers determined a novel feedback loop that helps explain how short-lived mRNA and proteins create long-term memories in the brain.

Source: albert einstein college of medicine.

Helping your mother make pancakes when you were three…riding your bike without training wheels…your first romantic kiss: How do we retain vivid memories of long-ago events?

Apr 26, 2023

Genetic Driver of Anxiety Discovered

Posted by in categories: biotech/medical, genetics, neuroscience

Summary: An international team of scientists has identified a gene in the brain responsible for anxiety symptoms and found that modifying the gene can reduce anxiety levels, offering a novel drug target for anxiety disorders. The discovery highlights a new amygdala miR483-5p/Pgap2 pathway that regulates the brain’s response to stress and provides a potential therapeutic approach for anxiety disorders.

Source: University of Bristol.

A gene in the brain driving anxiety symptoms has been identified by an international team of scientists. Critically, modification of the gene is shown to reduce anxiety levels, offering an exciting novel drug target for anxiety disorders.

Apr 26, 2023

Scientists Use Electricity to Make Wounds Heal 3x Faster

Posted by in category: biotech/medical

Scientists have developed a specially engineered biochip that uses electricity to heal wounds up to three times faster than normal.

It’s well known that electric fields can guide the movements of skin cells, nudging them towards the site of an injury for instance. In fact, the human body generates an electric field that does this naturally. So researchers from the University of Freiburg in Germany set out to amplify the effect.

While it might not heal severe injuries with the speed of a Marvel superhero, it could radically reduce the time it takes for small tears and lacerations to recover.

Apr 26, 2023

Winning the War on Cancer

Posted by in category: biotech/medical

Learn How to Prevent and Heal Cancer Using Natural, Holistic and Integrative Methods from World Leading Doctors and Cancer-Conquerors.

Apr 26, 2023

Opinion letter from Ray Kurzweil on request for 6 month delay on large language models that go beyond GPT-4 « Kurzweil

Posted by in categories: biotech/medical, education, health, Ray Kurzweil, robotics/AI

Kurzweil says NO, on AI pause non sense.


By Ray Kurzweil April 2023

Continue reading “Opinion letter from Ray Kurzweil on request for 6 month delay on large language models that go beyond GPT-4 « Kurzweil” »

Apr 25, 2023

New study reveals a gel that promises to wipe out brain cancer for good

Posted by in categories: biotech/medical, neuroscience

An anti-cancer gel promises to wipe out glioblastoma permanently, a feat that’s never been accomplished by any drug or surgery. So what makes this gel so special?

Scientists at Johns Hopkins University (JHU) have developed a novel gel that both eliminates brain cancer (glioblastoma) and keeps it from recurring. When they tested this anti-cancer gel on mice with glioblastoma, surprisingly, all the mouse models were cured of the illness.

Continue reading “New study reveals a gel that promises to wipe out brain cancer for good” »

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