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Rewriting Neuroscience: Possible “Foundations of Human Intelligence” Observed for the First Time

For the first time, it has been confirmed that individual neurons represent the concepts we learn, regardless of the context in which they are encountered, challenging previous beliefs.

A study led by Dr. Rodrigo Quian Quiroga, head of the Neural Mechanisms of Perception and Memory Research Group at the Hospital del Mar Research Institute, has provided the first direct evidence of how neurons in the human brain store memories independently of the context in which they are acquired.

Published in Cell Reports.

Ultra-dense data storage and extreme parallelism with electronic-molecular systems

Sustaining growth in storage and computational needs is increasingly challenging. For over a decade, exponentially more information has been produced year after year while data storage solutions are pressed to keep up. Soon, current solutions will be unable to match new information in need of storage. Computing is on a similar trajectory, with new needs emerging in search and other domains that require more efficient systems. Innovative methods are necessary to ensure the ability to address future demands, and DNA provides an opportunity at the molecular level for ultra-dense, durable, and sustainable solutions in these areas.

In this webinar, join Microsoft researcher Karin Strauss in exploring the role of biotechnology and synthetic DNA in reaching this goal. Although we have yet to achieve scalable, general-purpose molecular computation, there are areas of IT in which a molecular approach shows growing promise. These areas include storage as well as computation.

Learn how molecules, specifically synthetic DNA, can store digital data and perform certain types of special-purpose computation, like large-scale similarity search, by leveraging tools already developed by the biotechnology industry. Starting with some background on DNA and its storage potential, you’ll explore the advantages of using DNA for this application. Then, you’ll get a closer look at an end-to-end system, including encoding, synthesizing, reading, and decoding DNA. We’ll also look at an affordable full-stack digital microfluidics platform for wet lab preparations and conclude with a discussion of future hybrid systems.

Together, you’ll explore:

■ The intersection between technology and science of DNA data storage and computation.
■ The many advantages for using DNA to store data compared with other methods.
■ A detailed walkthrough of an end-to-end DNA storage system and its stages.
■ How DNA can be used for image similarity search.

Rewriting Textbooks: New Findings Challenge Decades of Mitochondrial Biology

A study conducted by researchers from the University of São Paulo sheds light on new discoveries about the mechanisms of oxidative phosphorylation in ATP production. Recent findings highlight the involvement of sodium in mitochondrial respiration.

In an article published in Trends in Biochemical Sciences, Alicia Kowaltowski, a full professor at the University of São Paulo’s Institute of Chemistry (IQ-USP) in Brazil, calls for a “rewriting” of textbooks regarding the location of the electron transport chain in mitochondria and the role of sodium in mitochondrial respiration.

Kowaltowski is also a member of the Research Center for Redox Processes in Biomedicine (Redoxoma), a Research, Innovation, and Dissemination Center (RIDC) funded by FAPESP and based at IQ-USP.

Quantum Computer Performs 2.6 Billion Years of Computation In Only 4 Minutes

Four minutes. Imagine what you can accomplish in four minutes. Make coffee? Read half an article? Send a few text messages?

For most of us, four minutes pass in a heartbeat. Yet during those same four minutes, a quantum computer recently performed calculations that would have kept a conventional supercomputer busy for 2.6 billion years.

Scientists achieved something magical—compressing billions of years of computation into minutes. Such power shifts our understanding of what’s possible. Quantum computing won’t just change how we process information; it will transform medicine, climate science, materials design, and countless other fields we rely on daily.

Ingredient Found in All Mushrooms Can Reprogram Immune Cells to Fight Deadly Flu Infections

A component found in all fungi may provide a shield that prevents flu-related lung damage, according to a new Canadian study.

The preclinical trial uncovered how beta-glucan—which is found in all mushrooms, and also yeast, oats, and barley—can ‘reprogram’ immune cells to prevent lung inflammation.

A team of scientists at the Research Institute of the McGill University Health Centre, demonstrated that administering the compound to mice before their exposure to influenza, reduced lung damage, improve lung function and lowered the risk of illness and death.

Low-Power Brain Chip Predicts Users’ Intentions

Despite its success, FNP has some limitations: it can’t create stable particles larger than 400 nm, the maximum drug content is about 70 percent, the output is low, and it can only work with very hydrophobic (water-repelling) molecules. These issues arise because the particle core formation and particle stabilization happen simultaneously in FNP. The new SNaP process overcomes these limitations by separating the core formation and stabilization steps.

In the SNaP process, there are two mixing steps. First, the core components are mixed with water to start forming the particle core. Then, a stabilizing agent is added to stop the core growth and stabilize the particles. This second step must happen quickly, less than a few milliseconds after the first step, to control the particle size and prevent aggregation. Current SNaP setups connect two specialized mixers in series, controlling the delay time between steps. However, these setups face challenges, including high costs and difficulties in achieving short delay times needed for small particle formation.

A new approach using 3D printing has solved many of these challenges. Advances in 3D printing technology now allow the creation of precise, narrow channels needed for these mixers. The new design eliminates the need for external tubing between steps, allowing for shorter delay times and preventing leaks. The innovative stacked mixer design combines two mixers into a single setup, making the process more efficient and user-friendly.

Inside the world of humanoid robots in Shanghai, China

Shanghai’s robotics revolution is here! At a cutting-edge startup, humanoid robots are being trained to navigate the real world-learning tasks from sorting objects to taking coffee. But how does Al collect and refine the data that powers these machines? We got access to a 2,000-square-meter data factory, where robots are trained through motion capture, human guidance, and real-world simulations. With China’s tech and supply chain advantages, could these humanoids become part of our daily lives sooner than we think? #HumanoidRobots #Al #FutureTech.
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Medical infusion bags can release microplastics, study shows

Microplastics have been found almost everywhere that scientists have looked for them. Now, according to research published in Environment & Health, these bits of plastic—from 1 to 62 micrometers long—are present in the filtered solutions used for medical intravenous (IV) infusions. The researchers estimate that thousands of plastic particles could be delivered directly to a person’s bloodstream from a single 8.4-ounce (250-milliliter) bag of infusion fluid.

In clinical settings, IV infusions are packaged in individual plastic pouches and deliver water, electrolytes, nutrients or medicine to patients. The base of these infusions is a that contains filtered water and enough salt to match the content of human blood. Research from the 1970s suggests IV fluid bags can contain solid particles, but few scientists have followed up on what those particles are made of.

Researchers Liwu Zhang, Ventsislav Kolev Valev and colleagues suspected that these particles could be microplastics that—upon —would enter the recipient’s bloodstream and potentially cause . So, they set out to analyze the types and amounts of particles in commercial IV fluid bags.

Scientists Discover a Trait in Speech That Foreshadows Cognitive Decline

Can you pass me the whatchamacallit? It’s right over there next to the thingamajig.

Many of us will experience “lethologica”, or difficulty finding words, in everyday life. And it usually becomes more prominent with age.

Frequent difficulty finding the right word can signal changes in the brain consistent with the early (“preclinical”) stages of Alzheimer’s disease – before more obvious symptoms emerge.

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