Lifeboat Foundation

Scientists found out that nonclassical monocites can become senescent.

Scientists from the A*STAR Singapore Immunology Network have discovered that immune cells called nonclassical monocytes undergo cellular senescence, contradicting what was previously thought of them [1].

Abstract

Continue reading “Type of Human Monocytes Found to Undergo Senescence” »

In the United States – the world’s biggest and most advanced pharmaceutical market – of the 46 new drugs given consent for marketing by regulators last year, 28 were developed by US firms and the realisation of all but four of the rest were led by European firms. None were Chinese.

China’s big ambitions to become a powerhouse of pharmaceutical innovation is as much about the well-being of its people as it is about narrowing the gap with the West.

It could be a new way to fight colony collapse disorder.

A humble mushroom extract might help with many of bees’ woes, according to new research — and even, maybe, help rebuild their world population.

The new nanomaterial-based hydrogel, which gets certain stem cells to grow into liver cells, could help people with a range of liver conditions.

Optical frequency combs can enable ultrafast processes in physics, biology, and chemistry, as well as improve communication and navigation, medical testing, and security. The Nobel Prize in Physics 2005 was awarded to the developers of laser-based precision spectroscopy, including the optical frequency comb technique, and microresonator combs have become an intense focus of research over the past decade.

A major challenge has been how to make such comb sources smaller and more robust and portable. In the past 10 years, major advances have been made in the use of monolithic, chip-based microresonators to produce such combs. While the microresonators generating the frequency combs are tiny—smaller than a human hair—they have always relied on external lasers that are often much larger, expensive, and power-hungry.

Researchers at Columbia Engineering announced today in Nature that they have built a Kerr frequency comb generator that, for the first time, integrates the laser together with the microresonator, significantly shrinking the system’s size and power requirements. They designed the laser so that half of the laser cavity is based on a semiconductor waveguide section with high optical gain, while the other half is based on waveguides, made of silicon nitride, a very low-loss material. Their results showed that they no longer need to connect separate devices in the lab using fiber—they can now integrate it all on photonic chips that are compact and energy efficient.

Continue reading “Engineers build smallest integrated Kerr frequency comb generator” »

Today, we are going to be taking a look at GAIM and what it might mean for treating amyloid-based diseases, such as Alzheimer’s, Parkinson’s, and amyloidosis. This approach has the potential to treat multiple age-related diseases at once by targeting a common characteristic that they all share.

Misfolded proteins cause multiple age-related diseases

Proteins are large, complex molecules that regulate almost everything in our bodies, either directly or indirectly. They do the majority of the work in cells and are critical for the function, regulation, and structure of tissues and organs.

Continue reading “Destroying Misfolded Proteins to Combat Neurodegenerative Diseases” »

Best Brain Game To Stave Off Alzheimer’s Could Be Your Job : Shots — Health News Alzheimer’s prevention specialist Jessica Langbaum says that like most working people she gets plenty of mental exercise without playing crossword puzzles or brain games. She says work is the key.

Japan’s draft guidelines for a proposal to begin editing genes found in human embryos was recently announced. The decision has some scientists concerned.

While still in its infancy, there is tremendous potential for stem cell technology to improve the quality of life for many. Blockchain technology can help accelerate this process.