Lifeboat Foundation

Find could lead to new treatments for obesity, depression.

Only time will tell what new forms life will take.

Joyce seeks to understand life by trying to generate simple living systems in the lab. In doing so, he and other synthetic biologists bring new kinds of life into being. Every attempt to synthesize novel life forms points to the fact that there are still more, perhaps infinite, possibilities for how life could be. Synthetic biologists could change the way life evolves, or its capacity to evolve at all. Their work raises new questions about a definition of life based on evolution. How to categorize life that is redesigned, the product of a break in the chain of evolutionary descent?

An origin story for synthetic biology goes like this: in 1997, Drew Endy, one of the founders of synthetic biology and now a professor of bioengineering at Stanford University in California, was trying to create a computational model of the simplest life form he could find: the bacteriophage T7, a virus that infects E coli bacteria. A crystalline head atop spindly legs, it looks like a landing capsule touching down on the Moon as it grabs onto its bacterial host. The bacteriophage is so simple that by some definitions it is not even alive. (Like all viruses, it depends on the molecular machinery of its host cell to replicate.) Bacteriophage T7 has only 56 genes, and Endy thought it might be possible to create a model that accounted for every part of the phage and how those parts worked together: a perfect representation that would predict how the phage would change if any one of its genes were moved or deleted.

Continue reading “If We Made Life in a Lab, Would We Understand It Differently?” »

Very interesting article on the ideas and daily life of the businessman and biohacker Serge Faguet.

Silicon Valley millionaire Serge Faguet thinks pills, injections and implants will turn him into a superhuman. Could they?

Given the speed at which reproductive technology has advanced over the past few decades, it doesn’t feel all that far-fetched: A future in which anyone can have a baby, regardless of creed or need, whenever they feel like it. Already, in our present moment, one can buy or sell eggs and sperm; we can give embryos genetic tests to ensure the children they produce don’t have any life-threatening hereditary conditions; and babies can even be born, now, with the genetic information from three parents.

So it follows that we should soon be able to to have pregnancy outside the body — artificial wombs. R ight?

Continue reading “Glimpse: On the Promise of a Future with Artificial Wombs, and Why It’s Being Stopped by the Present” »

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Continue reading “David Sinclair — Can NMN Reverse Aging?” »

A new fascinating feature is out by The Guardian magazine (via writer Richard Godwin) on the future of the human body. Six of us are interviewed and/or wrote about our take on the future. Fun reading! My mini-essay is in this: https://www.theguardian.com/…/regular-body-upgrades-what-wi… #transhumanism

Mechanical exoskeletons, bionic limbs, uploadable brains: six experts’ visions of 2118.

By Richard Godwin

Continue reading “‘We will get regular body upgrades’: what will humans look like in 100 years?” »

In a world increasingly driven by industries that rely on advanced technical learning and innovation, fluency in STEM fields (science, technology, engineering and math) becomes more vital every day. Yet our education system isn’t keeping up. Five years ago, a Business-Higher Education Forum study found that 80% of high school students either lacked interest or proficiency in STEM subjects. Meanwhile, a college and career readiness organization known as ACT reported last year that the number of students pursuing STEM careers is growing at less than 1% annually.

The Amgen Foundation is doing something about it. As the principal philanthropic arm of Amgen, the largest independent biotechnology company, the Amgen Foundation has been committed to inspiring the next generation of scientists and innovators by making immersive science education a focus of its social investments for almost 30 years. While Amgen has reached millions of patients around the world with biotechnology medicines to combat serious illnesses, such as cardiovascular disease, cancer and migraines, the Amgen Foundation has reached more than 4 million students globally—and it is poised to launch a new program called LabXchange with the potential to reach millions more.

“As a scientist, it’s clear to me that the most effective way to learn science is by doing it,” says David Reese, executive vice president of Research and Development at Amgen and member of the Amgen Foundation board of directors. “It’s time to transform the science learning experience. We need to move from information acquisition to application and exploration, from students as passive listeners to active participants in the learning process, from teachers as knowledge transmitters to facilitators and coaches.”

Continue reading “Philanthropy Assignment: Inspire Tomorrow’s Leaders With Science” »

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The transmission electron microscope was designed to break records. Using its beam of electrons, scientists have glimpsed many types of viruses for the first time. They’ve used it to study parts of biological cells like ribosomes and mitochondria. You can see individual atoms with it.

But experts have recently unlocked new potential for the machine. “It’s been a very dramatic and sudden shift,” says physicist David Muller of Cornell University. “It was a little bit like everyone was flying biplanes, and all of a sudden, here’s a jetliner.”

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Continue reading “New Microscope Shows the Quantum World in Crazy Detail” »