Lifeboat Foundation

Breast and ovarian cancers are scary, anxiety-provoking diseases, and with good reason. Although breast cancer isn’t the cancer that kills the most women (lung cancer holds that distinction), it is the most commonly diagnosed cancer in women. And ovarian cancer is difficult to find in its early stages. But anyone willing to spit in a tube and pay $199 will soon be able to find out if they have a particular genetic predisposition to either of these cancers.

This month, the FDA granted the genetics company 23andMe permission to offer direct-to-consumer testing for three of the more than 1,000 known variants of the genes BRCA1 and BRCA2The variants may also boost the risk of prostate cancer and melanoma.

British doctors have taken a huge step towards curing a common form of age-related chronic eye condition.

Two elderly patients with macular degeneration at Moorfields Eye Hospital in London were given a cutting-edge stem cell therapy as part of a small trial to improve vision for people with sudden and severe loss of vision caused by what’s known as “wet” macular degeneration, in which abnormal blood vessels grow under the retina and macula in the eye. “Wet” macular degeneration is less common than “dry” macular degeneration, but it is a more severe form of the disease that occurs as “dry” macular degeneration progresses. It rarely causes total blindness, but it can cause blurriness and blind spots that make it hard to see clearly. The idea was to replace those diseased eye cells using stem cells that were derived from a human embryo and then inserted into the back of the eye.

Embryonic stem cells are special because they have the ability to become any other cell type in the human body. In this case, they were coaxed into becoming the kind of cell that makes up the retinal pigment epithelium. They were embedded into a scaffold to hold them in place, a living patch of cells only one layer thick. That patch was then surgically inserted under the rods and cones in the back of the eye.

Continue reading “UK Doctors Used Stem Cells to Restore Eyesight in Two People” »

Take your probiotics seriously. Even a headache pill may weaken your gut bacteria, a condition linked to obisity, depression, alzheimer’s, and dementia.

https://www.albayan.ae/middle-east-dialogue/2018-03-20-1.3214947

A drug to slow the spread of dementia could be available in three years and a ‘vaccine’ that prevents the disease within a decade, experts say.

• It is now a matter of ‘when not if’ a cure will be found for Alzheimer’s
• Last year dementia became Great Britain’s number one cause of death
• Existing drugs for Alzheimer’s only treat the symptoms, not causes

By Colin Fernandez for the Daily Mail

Continue reading “A drug to slow spread of dementia could be available in three years” »

A neural circuit mechanism involved in preserving the specificity of memories has been identified by investigators from the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI).

They also identified a genetic “switch” that can slow down #memory generalization — the loss of specific details over time that occurs in both age-related memory impairment and in post-traumatic stress disorder (#PTSD), in which emotions originally produced by traumatic experiences are elicited in response to innocuous cues that have little resemblance to the traumatic memory.

“The circuit mechanism we identified in mice allows us to preserve the precision or the details of memories over the passage of time in adult as well as aged animals,” says Amar Sahay of the MGH Center for #Regenerative Medicine and HSCI, corresponding author of a paper appearing in Nature Medicine. “These findings have implications for the generalization of traumatic memories in PTSD and for memory imprecision in #aging.”

Continue reading “Targeting levels of specific protein could improve memory in aging, reduce symptoms of PTSD” »

D rugs to vaccinate everyone over the age of 50 against Alzheimer’s could be available within 10 years, but would cost the NHS £9 billion, a new report has shown.

New analysis commissioned by Alzheimer’s Research UK found that drugs to halt, slow or reverse the disease could be available in as little as three years with major vaccine and screening programmes possible within a decade.

But dementia experts warned that demand from patients would be ‘instant and huge’ and called on the NHS to act now to make sure funds were in place for when the breakthroughs occurred.

Continue reading “Drugs to vaccinate over-50s against Alzheimer’s could be here in a decade…with a £ 9bn price tag” »

Researchers in the United Kingdom used stem cells to treat two people with age-related macular degeneration.

Cancer remains the one counterpoint to the march of medical progress that has scored human history over the last 200 years.

Last year 600,920 people in the U.S. died from cancer, and another 1.7 million received an initial diagnosis of the disease. Globally, one in six people die from cancer, according to the World Health Organization.

In the past decade, research in the field has expanded the possible treatments of the disease from surgery (which was the only option until the 20th century), radiotherapy, chemotherapy and hormonal therapy.

Continue reading “Tradewind Bioscience attacks the physiology of tumors to treat cancer” »