Lifeboat Foundation

The last decade has brought a lot of attention to the use of microscopic robots (microrobots or nanorobots) for biomedical applications. Now, nanoengineers have developed microrobots that can swim around in the lungs and deliver medication to be used to treat bacterial pneumonia. A new study shows that the microrobots safely eliminated pneumonia-causing bacteria in the lungs of mice and resulted in 100% survival. By contrast, untreated mice all died within three days after infection.

The results are published Nature Materials in the paper, “Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia.”

The microrobots are made using click chemistry to attach antibiotic-loaded neutrophil membrane-coated polymeric nanoparticles to natural microalgae. The hybrid microrobots could be used for the active delivery of antibiotics in the lungs in vivo.

Scientists managed to start the same chemical process that powers the Sun on August 8, 2021, by putting more electricity into a tiny gold capsule than the entire US electric system could handle.

It is extremely astonishing how the power of 192 laser beams sparked the same thermonuclear fire that fuels the Sun for a nanosecond.

The Sun produces energy by hurling hydrogen atoms together, generating helium in the process. We are now closer than ever to being able to harness chemical reactions with enough force to power the Sun. This is possible because fusion power technology has advanced.

An interdisciplinary team of University of Minnesota Twin Cities scientists and engineers has developed a first-of-its-kind, plant-inspired extrusion process that enables synthetic material growth. The new approach will allow researchers to build better soft robots that can navigate hard-to-reach places, complicated terrain, and potentially areas within the human body.

The paper is published in the Proceedings of the National Academy of Sciences (PNAS), a peer-reviewed, multidisciplinary, high-impact scientific journal.

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Circa 2015 face_with_colon_three

Researchers have built the world’s first artificial neuron that’s capable of mimicking the function of an organic brain cell — including the ability to translate chemical signals into electrical impulses, and communicate with other human cells.

Continue reading “Scientists Have Built Artificial Neurons That Fully Mimic Human Brain Cells” »

Crucially, they showed that the synapses were capable of Hebbian learning, the process by which the strength of the connection between two neurons increases or decreases based on activity. This is key to the way information is encoded into the brain, with the strengths of connections between neurons controlling the function of different brain circuits.

In biological neurons this ability to alter the strength of connections—known as plasticity—operates at two distinct timescales. Over shorter timescales, regular firing of the neuron leads to a buildup of ions that temporarily increase the ease with which signals pass across. In the long term though, regular activity can cause new receptors to grow at a synapse, resulting in more durable increases in the strength of the connection.

With the artificial synapses, short-term plasticity operates in much the same way due to a buildup of ions. But boosting the connection strength in the long term relies on using voltage pulses to essentially grow new material out of a soup of chemical precursors at the synapse, which increases its conductivity.

When cancer develops in the body, it begins with tumor cells that rapidly multiply and divide before spreading. But how are these nascent tumor cells able to evade the body’s immune system, which is designed to recognize and defend against such faulty cells? The answer to this long-unsolved topic may hold the key to more successful cancer treatments — medications that block tumors’ subversive moves and allow the immune system to do its job.

Researchers at Harvard Medical School have now discovered a mechanism through which tumor cells can disable the immune system, enabling the tumor to spread unchecked. The study, which was conducted primarily in mice and published today in Science, demonstrates that tumor cells with a certain mutation generate a chemical, known as a metabolite, that weakens adjacent immune cells, making them less capable of eliminating cancer cells.

The results underscore the crucial roles played by tumor metabolites in the deactivation of the immune system by malignancies. The findings also highlight the crucial part that the tumor microenvironment—the region around the tumor—plays in the development of cancer.

A team of researchers from HSE MIEM joined colleagues from the Institute of Non-Classical Chemistry in Leipzig to develop a theoretical model of a polymeric ionic liquid on a charged conductive electrode. They used approaches from polymer physics and theoretical electrochemistry to demonstrate the difference in the behavior of electrical differential capacitance of polymeric and ordinary ionic liquids for the first time. The results of the study were published in Physical Chemistry Chemical Physics.

Polymerized ionic liquids (PIL) are a relatively new class of materials with increasing applications in various fields, from the development of new electrolytes to the creation of solar cells. Unlike ordinary room temperature ionic liquids (liquid organic salts in which cations and anions move freely), in PILs, cations are usually linked in long polymeric chains, while anions move freely. In recent years, PILs have been used (along with ordinary ionic liquids) as a filling in the production of supercapacitors.

Supercapacitors are devices that store energy in an electric double layer on the surface of an electrode (as in electrodes of platinum, gold and carbon, for example). Compared, for example, to an accumulator, supercapacitors accumulate more energy and do so faster. The amount of energy a supercapacitor is able to accumulate is known as its ‘capacitance’.

Researchers have used a novel near-infrared light imaging technique to capture the first cross-sectional images of carbon dioxide in the exhaust plume of a commercial jet engine. This new state-of-the-art technology could help accelerate turbine combustion research aimed at developing engines and aviation fuels that are more environmentally friendly.

“This approach, which we call chemical species tomography, provides real-time spatially resolved information for carbon dioxide emissions from a large-scale commercial engine,” said research team leader Michael Lengden from the University of Strathclyde in the U.K. “This information has not been available before at this industrial scale and is a big improvement over the current industry-standard emissions measurement, which involves taking gas from the exhaust to a gas analyzer system in a different location.”

The researchers report the new research in Applied Optics. Chemical species tomography works much like the X-ray-based CT scans used in medicine, except that it uses near-infrared laser light tuned to the absorption wavelength of a target molecule and requires very fast imaging speeds to capture the dynamic processes of combustion.

Microprocessors in smartphones, computers, and data centers process information by manipulating electrons through solid semiconductors, but our brains have a different system. They rely on the manipulation of ions in liquid to process information.

Inspired by the brain, researchers have long been seeking to develop “ionics” in an aqueous solution. While ions in water move slower than electrons in semiconductors, scientists think the diversity of ionic species with different physical and chemical properties could be harnessed for richer and more diverse information processing.

Ionic computing, however, is still in its early days. To date, labs have only developed individual ionic devices such as ionic diodes and transistors, but no one has put many such devices together into a more complex circuit for computing until now.