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The extracellular matrix (ECM) including three-dimensional (3D) network and bioelectricity can profoundly influence cell development, migration, and functional expression. In a new report now published on Science Advances, Tong Li and a research team in chemistry, nanotechnology, bioelectronics and advanced materials in China, developed an electromechanical coupling bio-nanogenerator abbreviated bio-NG inspired by biophysical cues of the extracellular matrix. The device contained highly discrete piezoelectric fibers to generate piezo potential of up to millivolts to provide in situ electrical stimulation for living cells.

By using a compound derived from a Himalayan fungus and used for centuries in Chinese medicine as a jumping off point, scientists have developed a new chemotherapy drug with powerful anti-cancer effects. Doing so involved chemically altering the compound to better infiltrate cancerous cells, which proved to boost its potency by up to 40 times.

New research by a City College of New York team has uncovered a novel way to combine two different states of matter. For one of the first times, topological photons—light—has been combined with lattice vibrations, also known as phonons, to manipulate their propagation in a robust and controllable way.

The study utilized topological photonics, an emergent direction in photonics which leverages fundamental ideas of the mathematical field of topology about conserved quantities—topological invariants—that remain constant when altering parts of a geometric object under continuous deformations. One of the simplest examples of such invariants is number of holes, which, for instance, makes donut and mug equivalent from the topological point of view. The topological properties endow photons with helicity, when photons spin as they propagate, leading to unique and unexpected characteristics, such as robustness to defects and unidirectional propagation along interfaces between topologically distinct materials. Thanks to interactions with vibrations in crystals, these helical photons can then be used to channel infrared light along with vibrations.

The implications of this work are broad, in particular allowing researchers to advance Raman spectroscopy, which is used to determine vibrational modes of molecules. The research also holds promise for vibrational spectroscopy—also known as infrared spectroscopy —which measures the interaction of infrared radiation with matter through absorption, emission, or reflection. This can then be utilized to study and identify and characterize chemical substances.

A Northwestern University research team has developed a versatile composite fabric that can deactivate both biological threats, such as the novel coronavirus that causes COVID-19, and chemical threats, such as those used in chemical warfare. A material that is effective against both classes of threats is rare.

The material also is reusable. It can be restored to its original state after the fabric has been exposed to threats by a simple bleach treatment. The promising fabric could be used in face masks and other protective clothing.

“Having a bifunctional material that has the ability to deactivate both chemical and biological toxic agents is crucial since the complexity to integrate multiple materials to do the job is high,” said Northwestern’s Omar Farha, an expert in metal-organic frameworks, or MOFs, which is the basis for the technology.

“The use of organophosphate esters in everything from TVs to car seats has proliferated under the false assumption that they’re safe,” said Heather Patisaul, lead author and neuroendocrinologist at North Carolina State University. “Unfortunately, these chemicals appear to be just as harmful as the chemicals they’re intended to replace but act by a different mechanism.”

Summary: Exposure to even low levels of common chemicals called organophosphate esters can harm IQ, memory, learning, and brain development overall in young children.

Source: Green Science Policy Institute

Continue reading “Common Chemicals in Electronics and Baby Products Harm Brain Development” »

Circa 2018 o.o

Rockets with nuclear bombs for propulsion sounds like a Wile E. Coyote cartoon, but it has been seriously considered as an option for the space program. Chemical rockets combust a fuel with an oxidizer within themselves and exhaust the result out the back, causing the rocket to move in the opposite direction. What if instead, you used the higher energy density of nuclear fission by detonating nuclear bombs?

Continue reading “Project Orion: Detonating Nuclear Bombs For Thrust” »

It can be difficult to distinguish between substance and hype in the field of artificial intelligence. In order to stay grounded, it is important to step back from time to time and ask a simple question: what has AI actually accomplished or enabled that makes a difference in the real world?

This summer, DeepMind delivered the strongest answer yet to that question in the decades-long history of AI research: AlphaFold, a software platform that will revolutionize our understanding of biology.

Continue reading “AlphaFold Is The Most Important Achievement In AI —Ever” »

Proteins are structured like folded chains. These chains are composed of small units of 20 possible amino acids, each labeled by a letter of the alphabet. A protein chain can be represented as a string of these alphabetic letters, very much like a string of music notes in alphabetical notation.

Protein chains can also fold into wavy and curved patterns with ups, downs, turns, and loops. Likewise, music consists of sound waves of higher and lower pitches, with changing tempos and repeating motifs.

Continue reading “The Music of Proteins Is Made Audible Through a Computer Program That Learns From Chopin” »

Without a new legal framework, they could destabilize societal norms.

Autonomous weapon systems – commonly known as killer robots – may have killed human beings for the first time ever last year, according to a recent United Nations Security Council report on the Libyan civil war. History could well identify this as the starting point of the next major arms race, one that has the potential to be humanity’s final one.

Autonomous weapon systems are robots with lethal weapons that can operate independently, selecting and attacking targets without a human weighing in on those decisions. Militaries around the world are investing heavily in autonomous weapons research and development. The U.S. alone budgeted US$18 billion for autonomous weapons between 2016 and 2020.

Continue reading “Could Autonomous Robots Be More Dangerous than Nukes?” »