Lifeboat Foundation

California (CNN) (07/17/20) — Scientists have discovered a type of bacteria that eats and gets its calories from metal, after suspecting they exist for more than a hundred years but never proving it.

Now microbiologists from the California Institute of Technology (or Caltech) accidentally discovered the bacteria after performing unrelated experiments using a chalk-like type of manganese, a commonly found chemical element.

Dr. Jared Leadbetter, professor of environmental microbiology at Caltech in Pasadena, left a glass jar covered with the substance to soak in tap water in his office sink, and left the vessel for several months when he went to work off campus.

To calculate the most stable atomic configuration, as well as estimate its hardness, the team relied on a computational method called density functional theory (DFT). DFT has been successfully used throughout chemistry and solid-state physics to predict the structure and properties of materials. Keeping track of the quantum states of all the electrons in a sample, and their interactions, is usually an intractable task. Instead, DFT uses an approximation that focuses on the final density of electrons in space orbiting the atoms. This simplifies the calculation to make it suitable for computers, while still providing very precise results.

Based on these calculations, the scientists found that the Young’s modulus, a measure of hardness, for pentadiamond is predicted to be almost 1700 GPa – compared with about 1200 GPa for conventional diamond.

“Not only is pentadiamond harder than conventional diamond, its density is much lower, equal to that of graphite,” explains co-author Professor Mina Maruyama.

(CNN) — Scientists have discovered a type of bacteria that eats and gets its calories from metal, after suspecting they exist for more than a hundred years but never proving it.

Now microbiologists from the California Institute of Technology (or Caltech) accidentally discovered the bacteria after performing unrelated experiments using a chalk-like type of manganese, a commonly found chemical element.

(CNN)Scientists have discovered a type of bacteria that eats and gets its calories from metal, after suspecting they exist for more than a hundred years but never proving it.

New research shows that one of the heaviest known elements can be manipulated to a greater degree than previously thought, potentially paving the way for new strategies to recycle nuclear fuel and better long-term storage of radioactive elements.

An international team of researchers has demonstrated how curium—element 96 in the periodic table and one of the last that can be seen with the naked eye—responds to the application of high pressure created by squeezing a sample between two diamonds.

Led by Florida State University Professor Thomas Albrecht-Schmitt and collaborators at the University at Buffalo and Aachen University, the team found that the behavior of curium’s outer electrons—which influence its ability to bond with other elements—can be altered by shortening the distance between it and surrounding lighter atoms. The findings are published in the journal Nature.

No industry will be spared.

The pharmaceutical business is perhaps the only industry on the planet, where to get the product from idea to market the company needs to spend about a decade, several billion dollars, and there is about 90% chance of failure. It is very different from the IT business, where only the paranoid survive but a business where executives need to plan decades ahead and execute. So when the revolution in artificial intelligence fueled by credible advances in deep learning hit in 2013–2014, the pharmaceutical industry executives got interested but did not immediately jump on the bandwagon. Many pharmaceutical companies started investing heavily in internal data science R&D but without a coordinated strategy it looked more like re-branding exercise with the many heads of data science, digital, and AI in one organization and often in one department. And while some of the pharmaceutical companies invested in AI startups no sizable acquisitions were made to date. Most discussions with AI startups started with “show me a clinical asset in Phase III where you identified a target and generated a molecule using AI?” or “how are you different from a myriad of other AI startups?” often coming from the newly-minted heads of data science strategy who, in theory, need to know the market.

However, some of the pharmaceutical companies managed to demonstrate very impressive results in the individual segments of drug discovery and development. For example, around 2018 AstraZeneca started publishing in generative chemistry and by 2019 published several impressive papers that were noticed by the community. Several other pharmaceutical companies demonstrated impressive internal modules and Eli Lilly built an impressive AI-powered robotics lab in cooperation with a startup.

Continue reading “Deep Dive Into Big Pharma AI Productivity: One Study Shaking The Pharmaceutical Industry” »

Choi and other researchers have also tried to use lithium-ion battery electrodes to pull lithium directly from seawater and brines without the need for first evaporating the water. Those electrodes consist of sandwichlike layered materials designed to trap and hold lithium ions as a battery charges. In seawater, a negative electrical voltage applied to a lithium-grabbing electrode pulls lithium ions into the electrode. But it also pulls in sodium, a chemically similar element that is about 100,000 times more abundant in seawater than lithium. If the two elements push their way into the electrode at the same rate, sodium almost completely crowds out the lithium.

Lithium is prized for rechargeables because it stores more energy by weight than other battery materials. Manufacturers use more than 160,000 tons of the material every year, a number expected to grow nearly 10-fold over the next decade. But lithium supplies are limited and concentrated in a handful of countries, where the metal is either mined or extracted from briny water.

Lithium’s scarcity has raised concerns that future shortages could cause battery prices to skyrocket and stymie the growth of electric vehicles and other lithium-dependent technologies such as Tesla Powerwalls, stationary batteries often used to store rooftop solar power.

Continue reading “Seawater could provide nearly unlimited amounts of critical battery material” »

Evidence of SARS-CoV-2 transmission from mother to fetus 😢.

SARS-CoV-2 outbreak is the first pandemic of the century. SARS-CoV-2 infection is transmitted through droplets; other transmission routes are hypothesized but not confirmed. So far, it is unclear whether and how SARS-CoV-2 can be transmitted from the mother to the fetus. We demonstrate the transplacental transmission of SARS-CoV-2 in a neonate born to a mother infected in the last trimester and presenting with neurological compromise. The transmission is confirmed by comprehensive virological and pathological investigations. In detail, SARS-CoV-2 causes: maternal viremia, placental infection demonstrated by immunohistochemistry and very high viral load; placental inflammation, as shown by histological examination and immunohistochemistry, and neonatal viremia following placental infection. The neonate is studied clinically, through imaging, and followed up. The neonate presented with neurological manifestations, similar to those described in adult patients.

The 400 kilogram wheeled system moves about the lab guided by LIDAR laser scanners and has an industrial robotic arm made by German firm Kuka that it uses to carry out tasks like weighing out solids, dispensing liquids, removing air from the vessel, and interacting with other pieces of equipment.

In a paper in Nature, the team describes how they put the device to work trying to find catalysts that speed up reactions that use light to split water into hydrogen and oxygen. To do this, the robot used a search algorithm to decide how to combine a variety of different chemicals and updated its plans based on the results of previous experiments.

Continue reading “This Robotic Chemist Does Over 600 Experiments a Week and Learns From Its Own Work” »

Chemists at the University of Wisconsin-Madison and their collaborators have created a highly efficient and long-lasting solar flow battery, a way to generate, store and redeliver renewable electricity from the sun in one device.

The new device is made of silicon solar cells combined with advanced solar materials integrated with optimally designed chemical components. The solar flow battery, made by the Song Jin lab in the UW-Madison chemistry department, achieved a new record efficiency of 20 percent. That bests most commercially available silicon solar cells used today and is 40 percent more efficient than the previous record holder for solar flow batteries, also developed by the Jin lab.