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Computational framework sheds light on how the brain’s decision-making is impacted in psychiatric disorders

Scientists from the Icahn School of Medicine at Mount Sinai, working in collaboration with a team from the University of Texas at El Paso, have developed a novel computational framework for understanding how a region of the brain known as the striatum is involved in the everyday decisions we make and, importantly, how it might factor into impaired decision-making by individuals with psychiatric disorders like post-traumatic stress disorder and substance use disorder.

In a study published in Nature Communications, the team reported that modulating activity within the striosomal compartment—a neurochemically discrete area of the striatum—might be an important therapeutic strategy for promoting healthier in people with psychiatric disorders.

“Though it has been established that the striatum is clearly important for cost-benefit decision-making, the precise role of the striosomal compartment has remained elusive,” says Ki Goosens, Ph.D., Associate Professor of Pharmacological Sciences and Psychiatry, at the Icahn School of Medicine at Mount Sinai and co-lead author of the study.

Laser advance sets the stage for new X-ray science possibilities

A team led by scientists at the Department of Energy’s SLAC National Accelerator Laboratory have generated a highly exotic type of light beam, called a Poincaré beam, using the FERMI free-electron laser (FEL) facility in Italy, marking the first time such a beam has been produced with a FEL.

The technique could improve how scientists study materials and drive advancements in high-performance technologies, such as next-generation computer chips. The results are published in Nature Photonics.

“This is a significant step forward,” said SLAC scientist and collaborator Erik Hemsing. “Poincaré beams allow us to probe materials in new ways, capturing complex behaviors in one pulse. It’s exciting to think about what researchers will do with this.”

10x increase in atom array size boosts China’s quantum leap

Chinese researchers unveil 10x larger atom array for next-gen quantum processors.


Scientists in China have achieved a significant breakthrough in advancing quantum physics.

A team of researchers has developed the largest array of atoms for quantum computing.

The key component for a quantum computer is reportedly capable of creating arrays 10 times larger than previous systems.

Building energy model offers cities decarbonization roadmap

A new software tool developed by Cornell researchers can model a small city’s building energy use within minutes on a standard laptop, then run simulations to help policymakers prioritize the most cost-effective approaches to decarbonization.

Using the City of Ithaca, New York, as a , the urban building energy model quickly mapped more than 5,000 residential and and their baseline energy use. Simulated investments in weatherization, electric heat pumps and rooftop solar panels, while also factoring in financial incentives, generated insights that are informing city efforts to achieve carbon neutrality by 2030.

The tool’s automated workflow, accessibility and accuracy—without advanced computing power—could be particularly valuable for smaller cities that lack resources and expertise dedicated to decarbonization, the researchers said. But they said the new model—now also supporting the county that surrounds Ithaca—could be further scaled up to serve big cities or an entire state.

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