Lifeboat Foundation

While modern, scientific understanding of this complex network of neurons between our ears really only began in the last few decades, we’ve already learned a lot about the body’s control center — and have been given a lot to think about.

In this episode of The Abstract, we discuss the groundbreaking research in brain-computer technology offering new hope in restoring sensations and treating anxiety.

Our first story is about groundbreaking research in brain-computer interfaces that’s offering new hope for those who have lost their sense of touch. By decoding neural signals from the brain, researchers were able to create movement and sensory perception in paralyzed limbs. Innovations like these in sense-restoring technology could be life-changing for spinal cord patients and make a devastating loss of sensation reversible.

Accelerating progress in neuroscience is helping us understand the big picture—how animals behave and which brain areas are involved in bringing about these behaviors—and also the small picture—how molecules, neurons, and synapses interact. But there is a huge gap of knowledge between these two scales, from the whole brain down to the neuron.

A team led by Christos Papadimitriou, the Donovan Family Professor of Computer Science at Columbia Engineering, proposes a new computational system to expand the understanding of the brain at an intermediate level, between neurons and cognitive phenomena such as language. The group, which includes computer scientists from Georgia Institute of Technology and a neuroscientist from the Graz University of Technology, has developed a brain architecture that is based on neuronal assemblies, and they demonstrate its use in the syntactic processing in the production of language; their model, published online June 9 in PNAS, is consistent with recent experimental results.

“For me, understanding the brain has always been a computational problem,” says Papadimitriou, who became fascinated by the brain five years ago. “Because if it isn’t, I don’t know where to start.”

Data governs our lives more than ever. But when it comes to disease and death, every data point is a person, someone who became sick and needed treatment.

Recent studies have revealed that people suffering from the same disease category may have different manifestations. As doctors and scientists better understand the reasons underlying this variability, they can develop novel preventive, diagnostic and therapeutic approaches and provide optimal, personalized care for every patient.

To accomplish this goal often requires broadscale collaborations between physicians, basic researchers, theoreticians, experimentalists, computational biologists, computer scientists and data scientists, engineers, statisticians, epidemiologists and others. They must work together to integrate scientific and medical knowledge, theory, analysis of medical big data and extensive experimental work.

Continue reading “Israeli researchers explain how they are healing the world with precision” »

It’s easy to take time’s arrow for granted — but the gears of physics actually work just as smoothly in reverse. Maybe that time machine is possible after all?

An experiment from 2019 shows just how much wiggle room we can expect when it comes to distinguishing the past from the future, at least on a quantum scale. It might not allow us to relive the 1960s, but it could help us better understand why not.

Researchers from Russia and the US teamed up to find a way to break, or at least bend, one of physics’ most fundamental laws of energy.

Frequency multipliers, circuits that can produce signals with multiple frequencies, are essential components for a number of technological tools, particularly wireless communications systems. Most existing multipliers, however, are built using filtering and amplification circuits that are bulky and rapidly drain a lot of power.

Researchers at NaMLab in Germany have recently devised a single ferroelectric field-effect transistor that can serve both as a full-wave rectifier and frequency multiplier. The device they developed, presented in a paper published in Nature Electronics, is fully reconfigurable and energy-efficient, as it can be used in isolation, not requiring any additional circuits.

“Our institute (NaMLab) has been doing research on ferroelectric hafnium oxide (HfO₂) since this material’s ferroelectric properties were discovered in 2007,” Halid Mulaosmanovic, one of the researchers who carried out the study, told TechXplore. “An attractive electronic device that can be made using this material is a ferroelectric field-effect transistor (FeFET), which resembles conventional logic transistors, but has a ferroelectric layer in the gate stack.”

Approach to identifying the best drug targets gets critical test.

Miniaturization has enabled technology like smartphones, health watches, medical probes and nano-satellites, all unthinkable a couple decades ago. Just imagine that in the course of 60 years, the transistor has shrunk from the size of your palm to 14 nanometers in dimension, 1000 times smaller than the diameter of a hair.

Miniaturization has pushed technology to a new era of optical circuitry. But in parallel, it has also triggered new challenges and obstacles, for example, controlling and guiding light at the nanometer scale. Researchers are looking for techniques to confine light into extremely tiny spaces, millions of times smaller than current ones. Studies had earlier found that metals can compress light below the wavelength-scale (diffraction limit).

In that aspect, graphene, a material composed from a single layer of carbon atoms, which exhibits exceptional optical and electrical properties, is capable of guiding light in the form of plasmons, which are oscillations of electrons that strongly interact with light. These graphene plasmons have a natural ability to confine light to very small spaces. However, until now, it was only possible to confine these plasmons in one direction, while the actual ability of light to interact with small particles like atoms and molecules resides in the volume into which it can be compressed. This type of confinement in all three dimensions is commonly regarded as an optical cavity.

A pair of new security threats to Intel-based computer systems have been revealed. The beleaguered semiconductor chip manufacturer has faced a seemingly endless series of vulnerabilities over the past two years.

Although no known attacks have occurred, two teams of researchers have confirmed vulnerabilities in what is supposed to be the safest neighborhood within Intel processor architecture.

One attack, dubbed SGAxe, can gain entry into Intel’s Software Guard eXtensions (SGX) services that were specifically designed to protect critical data in the event of massive assault elsewhere in a system. A hacker theoretically can steal cryptographic keys stored in SGX and use them to break security measures protecting sensitive data such as financial records, copyrighted content or passwords.

Engineers at Duke University have demonstrated a versatile microfluidic lab-on-a-chip that uses sound waves to create tunnels in oil to touchlessly manipulate and transport droplets. The technology could form the basis of a small-scale, programmable, rewritable biomedical chip that is completely reusable to enable on-site diagnostics or laboratory research.

The results appear online on June 10 in the journal Science Advances.

“Our new system achieves rewritable routing, sorting and gating of droplets with minimal external control, which are essential functions for the digital logic control of droplets,” said Tony Jun Huang, the William Bevan Distinguished Professor of Mechanical Engineering and Materials Science at Duke. “And we achieve it with less energy and a simpler setup that can control more droplets simultaneously than previous systems.”