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Randal and Keith discuss WBE, Mind Uploading and fascinating tangents in neuroscience and neuroprosthetics and pathways for the future, as well as the Carbon Copies foundation and the new book ‘Contemplating Oblivion’ by Keith Wiley.

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The world’s first brain prosthesis has passed the first stages of live testing.

The microchip, designed to model a part of the brain called the hippocampus, has been used successfully to replace a neural circuit in slices of rat brain tissue kept alive in a dish. The prosthesis will soon be ready for testing in animals.

The device could ultimately be used to replace damaged brain tissue which may have been destroyed in an accident, during a stroke, or by neurodegenerative conditions such as Alzheimer’s disease. It is the first attempt to replace central brain regions dealing with cognitive functions such as learning or speech.

Further, “the necessity to secure private ideas, plans, and brain data from unpermitted viewing is accorded to Dr. Anita S Jwa by the phrase,” she argues. Besides that, the ethical implications in the fields of informed consent, coercion, and fairness with respect to the common attributes of the BCIs must be critically considered. For example, consider a scenario where a BCI is used to control a prosthetic limb. Without proper privacy measures, “unauthorised access to the BCI could lead to manipulation of the prosthetic limb,” posing risks to the user’s safety and autonomy.

Overcoming these difficulties requires the joint efforts of all the stakeholders, such as researchers, policymakers, and industry leaders. In the same way, we have to critically assess the technical, ethical, and accessibility issues in BCI. We may then be able to capture the potential of these BCIs and ultimately improve human lives.

In this instance, just imagine that we are submerging into the future of BCIs, and to my surprise, it feels like living in a movie where sci-fi is a reality! BCIs are going to be able to do all kinds of really advanced things very soon. People are going to think that they are very cool. We are entering an entirely new realm of brainy gadgets that are becoming smaller, sleeker, and oh-so-wearable. It is now all gear change; the future of BCI is almost as organic as slipping on your dream pair of sunglasses.

Electrically powered artificial muscle fibers (EAMFs) are emerging as a revolutionary power source for advanced robotics and wearable devices. Renowned for their exceptional mechanical properties, integration flexibility, and functional versatility, EAMFs are at the forefront of cutting-edge innovation.

A recent review article on this topic was published online in the National Science Review (“Emerging Innovations in Electrically Powered Artificial Muscle Fibers”).

Schematic of electrically powered artificial muscle fibers categorized from the mechanism, material components, and configurations, as well as their application fields. (Image: Science China Press)

The dramatic advances in efferent neural interfaces over the past decade are remarkable, with cortical signals used to allow paralyzed patients to control the movement of a prosthetic limb or even their own hand. However, this success has thrown into relief, the relative lack of progress in our ability to restore somatosensation to these same patients. Somatosensation, including proprioception, the sense of limb position and movement, plays a crucial role in even basic motor tasks like reaching and walking. Its loss results in crippling deficits. Historical work dating back decades and even centuries has demonstrated that modality-specific sensations can be elicited by activating the central nervous system electrically. Recent work has focused on the challenge of refining these sensations by stimulating the somatosensory cortex (S1) directly. Animals are able to detect particular patterns of stimulation and even associate those patterns with particular sensory cues. Most of this work has involved areas of the somatosensory cortex that mediate the sense of touch. Very little corresponding work has been done for proprioception. Here we describe the effort to develop afferent neural interfaces through spatiotemporally precise intracortical microstimulation (ICMS). We review what is known of the cortical representation of proprioception, and describe recent work in our lab that demonstrates for the first time, that sensations like those of natural proprioception may be evoked by ICMS in S1. These preliminary findings are an important first step to the development of an afferent cortical interface to restore proprioception.

Keywords: Intracortical microstimulation (ICMS); Prosthesis; Somatosensation; Somatosensory cortex.

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We often contemplate cyborgs, people enhanced by machines, but what would a civilization built upon cybernetics be like?

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Credits:
Cyborg Civilizations.
Episode 454a; July 7, 2024
Produced, Written \& Narrated by: Isaac Arthur.
Graphics:
Bryan Versteeg.
Jeremy Jozwik.
Music Courtesy of Epidemic Sound http://epidemicsound.com/creator.
Select imagery/video supplied by Getty Images.

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