Lifeboat Foundation

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UCL researchers have created a strange robotic “third thumb” that attaches to the hand and adds a large extra digit on the opposite side of the hand from the thumb. Researchers found that using the robotic thumb can impact how the hand is represented in the brain. For the research, scientists trained people to use an extra robotic thumb and found they could effectively carry out dexterous tasks such as building a tower of blocks using a single hand with two thumbs.

Researchers said that participants trained to use the extra thumb increasingly felt like it was part of their body. Initially, the Third Thumb was part of a project seeking to reframe the way people view prosthetics from replacing a lost function to becoming an extension of the human body. UCL Professor Tamar Makin says body augmentation is a growing field aimed at extending the physical abilities of humans.

Using a robotic ‘Third Thumb’ can impact how the hand is represented in the brain, finds a new study led by UCL researchers.

The team trained people to use a robotic extra thumb and found they could effectively carry out dextrous tasks, like building a tower of blocks, with one hand (now with two thumbs). The researchers report in the journal Science Robotics that participants trained to use the thumb also increasingly felt like it was a part of their body.

Designer Dani Clode began developing the device, called the Third Thumb, as part of an award-winning graduate project at the Royal College of Art, seeking to reframe the way we view prosthetics, from replacing a lost function, to an extension of the human body. She was later invited to join Professor Tamar Makin’s team of neuroscientists at UCL who were investigating how the brain can adapt to body augmentation.

To begin with, why do we use mice in medical and biological research? The answer to this question is fairly straight forward. Mice are cheap, they grow quickly, and the public rarely object to experimentations involving mice. However, mice offer something that is far more important than simple pragmatism, as despite being significantly smaller and externally dissimilar to humans, our two species share an awful lot of similarities. Almost every gene found within mice share functions with genes found within humans, with many genes being essentially identical (with the obvious exception of genetic variation found within all species). This means that anatomically mice are remarkably similar to humans.

Now, this is where for the sake of clarity it would be best to break down biomedical research into two categories. Physiological research and pharmaceutical research, as the success of the mouse model should probably be judges separately depending upon the research that is being carried out. Separating the question of the usefulness of the mouse model down into these two categories also solves the function of more accurately focusing the ire of its critics.

The usefulness of the mouse model in the field of physiological research is largely unquestioned at this point. We have quite literally filled entire textbooks with the information we have gained from studying mice, especially in the field of genetics and pathology. The similarities between humans and mice are so prevalent that it is in fact possible to create functioning human/mouse hybrids, known as ‘genetically engineered mouse models’ or ‘GEMMs’. Essentially, GEMMs are mice that have had the mouse version of a particular gene replaced with its human equivalent. This is an exceptionally powerful tool for medical research, and has led to numerous medical breakthroughs, including most notably our current treatment of acute promyelocytic leukaemia (APL), which was created using GEMMs.

Nuclear Nonproliferation, Cooperative Threat Reduction and WMD Terrorism — Dr. Natasha Bajema, Director, Converging Risks Lab, The Council on Strategic Risks.

Dr. Natasha Bajema, is a subject matter expert in nuclear nonproliferation, cooperative threat reduction and WMD terrorism, and currently serves as Director of the Converging Risks Lab, at The Council on Strategic Risks, a nonprofit, non-partisan security policy institute devoted to anticipating, analyzing and addressing core systemic risks to security in the 21st century, with special examination of the ways in which these risks intersect and exacerbate one another.

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Multi-resistant pathogens are a serious and increasing problem in today’s medicine. Where antibiotics are ineffective, these bacteria can cause life-threatening infections. Researchers at Empa and ETH Zurich are currently developing nanoparticles that can be used to detect and kill multi-resistant pathogens that hide inside our body cells. The team published the study in the current issue of the journal Nanoscale (“Inorganic nanohybrids combat antibiotic-resistant bacteria hiding within human macrophages”).

Antibiotic-resistant bacteria are being swallowed by a human white blood cell. Colorized, scanning electron microscopic (SEM) image. (Image: CDC/NIAID)

In the arms race “mankind against bacteria”, bacteria are currently ahead of us. Our former miracle weapons, antibiotics, are failing more and more frequently when germs use tricky maneuvers to protect themselves from the effects of these drugs. Some species even retreat into the inside of human cells, where they remain “invisible” to the immune system. These particularly dreaded pathogens include multi-resistant staphylococci (MRSA), which can cause life-threatening diseases such as sepsis or pneumonia.

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Cosmos Elementary https://youtube.com/channel/UCBTUsDJaEqU-1rWBW1F0oog.

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