Lifeboat Foundation

Plenary Talk by Michael Levin on “Non-neural, developmental bioelectricity as a precursor for cognition: Evolution, synthetic organisms, and biomedicine” at the Virtual Miniature Brain Machinery Retreat, September 16, 2021. Introduction by William Baker.

Michael Levin.
Director of the Allen Discovery Center.
Tufts University.

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Michael Levin talk for the Mind, Technology, and Society (MTS) talk series at UC Merced on January 23, 2023. Abstract: Each of us makes the remarkable journey from the physics and chemistry of a quiescentunfertilized egg to that of a complex human being. How can we understand the continuousprocesses that scale up minds from the tiny physiological competencies of single cells to the large-scale metacognitive capacities of large brains? Here, I will describe a framework known as TAME-Technological Approach to Mind Everywhere — which enables identifying, understanding, andrelating to unconventional cognitive agents. I will use the example of the collective intelligence ofcells during morphogenesis to illustrate how we can begin to widen the lessons of multiscale neuroscience well beyond neurons. This will be essential as we head into a future that will bepopulated by a wide range of evolved, designed, and hybrid beings with novel bodies and novelminds. I will conclude with a case study of our new synthetic biorobot (Xenobots) and a discussionof the implications of these ideas for evolution, biomedicine, and ethics.

Scientists have recently reviewed the available literature to examine the critical roles played by mitochondria in maintaining homeostasis. The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases. This review has been published in Experimental & Molecular Medicine.

Mitochondria is a cytoplasmic organelle in most eukaryotic cells and is enclosed by two phospholipid membranes: the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM). These membranes separate functionally compartmentalized structures, i.e., matrix and intermembrane space. Mitochondria contain a unique genetic code, mitochondrial DNA (mtDNA).

During evolution, most mitochondrial genes were lost or translocated to nuclei. However, genes that remained in mtDNA encode for essential translational apparatus, i.e., ribosomal RNAs and transfer RNAs. In addition, these genes also encode proteins that are key components of oxidative phosphorylation system (OXPHOS) complexes embedded in the IMM.

We know that humans are an intelligent species. But this biologist breaks down the intelligence of each of our cells — and it will blow your mind.

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❍ Up next: An evolutionary history of the human brain, in 7 minutes https://www.youtube.com/watch?v=NGArM23mMNM

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How would it feel to control objects with your mind? Or hear colors? Or maybe even live forever? Well, if you want to find out, all you have to do is become a cyborg. How would being part machine affect us? Would it cause a greater divide between the rich and the poor? And is this the next step in human evolution?

Transcript and sources: https://whatifshow.com/what-if-we-become-cyborgs/

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Proposal springs from an analysis of constraints imposed by life’s fluid motion.

What happened before the Big Bang? In two of our previous films we examined cyclic cosmologies and time travel universe models. Specially, the Gott and Li Model https://www.youtube.com/watch?v=79LciHWV4Qs) and Penrose’s Conformal Cyclic Cosmology https://www.youtube.com/watch?v=FVDJJVoTx7s). Recently Beth Gould and Niayesh Afshordi of the Perimeter Institute for Theoretical Physics have fused these two models together to create a startling new vision of the universe. In this film they explain their new proposal, known as Periodic Time Cosmology.

0:00 Introduction.
0:45 NIayesh’s story.
1:15 Beth’s story.
2:25 relativity.
3:26 Gott & Li model.
6:23 origins of the PTC model.
8:17 PTC periodic time cosmology.
10:55 Penrose cyclic model.
13:01 Sir Roger Penrose.
14:19 CCC and PTC
15:45 conformal rescaling and the CMB
17:28 assumptions.
18:41 why a time loop?
20:11 empirical test.
23:96 predcitions.
26:19 inflation vs PTC
30:22 gravitational waves.
31:40 cycles and the 2nd law.
32:54 paradoxes.
34:08 causality.
35:17 immortality in a cyclic universe.
38:02 eternal return.
39:21 quantum gravity.
39:57 conclusion.

Continue reading “Before the Big Bang 11: Did the Universe Create itself? The PTC model” »

Our lifespans might feel like a long time by human standards, but to the Earth it’s the blink of an eye. Even the entirety of human history represents a tiny slither of the vast chronology for our planet. We often think about geological time when looking back into the past, but today we look ahead. What might happen on our planet in the next billion years?

Written and presented by Prof David Kipping, edited by Jorge Casas.

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Does our increasing dependency on technology diminish our human potential? In this episode, visionary scientist Gregg Braden discusses the current transhuman movement – the merging of technology and human biology, often referred to as the singularity. He describes three levels of tech integration where the final level replaces our natural biology. In a time of rapid evolution, reflection and discernment are key. Braden highlights what we can do to release the conditioning of a technology-dependent society and how to follow the natural rhythms within ourselves.