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New “evolution engine” creates super-proteins 100,000x faster

Researchers at Scripps have created T7-ORACLE, a powerful new tool that speeds up evolution, allowing scientists to design and improve proteins thousands of times faster than nature. Using engineered bacteria and a modified viral replication system, this method can create new protein versions in days instead of months. In tests, it quickly produced enzymes that could survive extreme doses of antibiotics, showing how it could help develop better medicines, cancer treatments, and other breakthroughs far more quickly than ever before.

New Discovery Rewrites the Rules of Protein Stability and Evolution

A large-scale experiment has uncovered the fundamental rules that govern protein stability, opening the door to more rapid development of drugs and enzymes. Proteins are essential molecular machines that power countless processes in living organisms. They help turn sunlight into energy, support t

A Paradigm Shift in Evolutionary Biology: The Extended Evolutionary Synthesis and the Role of Epigenetics

The field of evolutionary biology has a rich and complex history, marked by periods of consensus and significant theoretical shifts. The cornerstone of modern evolutionary thought for much of the 20th century was the Modern Synthesis (MS), a theoretical framework that integrated Darwin’s theory of natural selection with Mendelian genetics.

It provided a powerful and elegant explanation for how evolution occurs, emphasizing the gradual accumulation of genetic mutations and their differential survival in a population. However, in recent decades, a growing body of evidence has begun to challenge the sufficiency of the MS, leading to the development of a new, more comprehensive framework: the Extended Evolutionary Synthesis (EES).

Meet the universe’s earliest confirmed black hole: A monster at the dawn of time

An international team of astronomers, led by The University of Texas at Austin’s Cosmic Frontier Center, has identified the most distant black hole ever confirmed. It and the galaxy it calls home, CAPERS-LRD-z9, are present 500 million years after the Big Bang. That places it 13.3 billion years into the past, when our universe was just 3% of its current age. As such, it provides a unique opportunity to study the structure and evolution of this enigmatic period.

“When looking for , this is about as far back as you can practically go. We’re really pushing the boundaries of what current technology can detect,” said Anthony Taylor, a postdoctoral researcher at the Cosmic Frontier Center and lead on the team that made the discovery.

The research is published in The Astrophysical Journal.

Deep-sky survey detects an X-ray emitting pair of galaxies

By conducting multiwavelength observations with various telescopes and space observatories, astronomers from Tsinghua University and Steward Observatory have detected a galaxy pair exhibiting significant X-ray emission. The finding was reported in a research paper published July 31 on the pre-print server arXiv.

The Great Observatories Origins Deep Survey (GOODS) is a deep-sky survey conducted by multiple observatories to study the formation and evolution of galaxies. It combines multiwavelength data from space observatories like the Hubble Space Telescope (HST), Chandra X-ray Observatory, Spitzer spacecraft, XMM-Newton satellite, and the largest ground-based facilities, such as the Very Large Telescope (VLT), Keck telescopes, Gemini Observatory or the Very Large Array (VLA).

Recently, a team of astronomers led by Tsinghua University’s Sijia Cai conducted a search for Chandra X-ray detected star-forming galaxies in the Southern field of the GOODS survey (GOODS-S). For this purpose, they combined observations from VLA and the Atacama Large Millimeter/submillimeter Array (ALMA), spectroscopic data from the James Webb Space Telescope (JWST) and VLT, as well as photometry from HST and JWST.

It Shouldn’t Exist: Astronomers Discover a Planet Orbiting the “Wrong Way”

Most stars throughout the Universe are part of binary or multiple star systems. In these systems, a nearby companion star can make it difficult for planets to form and remain in stable orbits around just one of the stars.

A research team made up of international astrophysicists, led by Professor Man Hoi Lee from the University of Hong Kong’s Department of Earth Sciences and Department of Physics, along with MPhil student Ho Wan Cheng, has confirmed a highly unusual planetary discovery.

They identified a planet orbiting in the opposite direction of its binary stars’ movement, known as a retrograde orbit, within the nu Octantis (nu Octantis) binary system. Their work also sheds light on how the evolution of binary stars may have influenced the planet’s origin. These results have been published in the journal Nature.

Mysterious object found dancing with Neptune

Astronomers have discovered a bizarre object in the outer solar system, 2020 VN40, that dances to Neptune’s gravitational beat in a never-before-seen rhythm. It’s the first of its kind, orbiting the Sun once for every ten orbits of Neptune, and could reshape how we understand the movement and evolution of distant cosmic bodies.

Direct electrolysis systems turns waste alkaline water into clean hydrogen

Dr. Sung Mook Choi and his research team at the Energy & Environmental Materials Research Division of the Korea Institute of Materials Science (KIMS) have successfully developed a highly durable non-precious metal-based hydrogen evolution catalyst for use in a direct electrolysis system employing waste alkaline water and anion exchange membranes (AEM). This breakthrough enables the production of clean hydrogen by directly utilizing alkaline wastewater generated from industrial processes.

Scientists create an artificial cell capable of navigating its environment using chemistry alone

Researchers at the Institute for Bioengineering of Catalonia (IBEC) have created the world’s simplest artificial cell capable of chemical navigation, migrating toward specific substances like living cells do.

This breakthrough, published in Science Advances, demonstrates how microscopic bubbles can be programmed to follow chemical trails. The study describes the development of a “minimal cell” in the form of a lipid encapsulating enzymes that can propel itself through chemotaxis.

Cellular transport is a vital aspect of many biological processes and a key milestone in evolution. Among all types of movement, chemotaxis is an essential strategy used by many living systems to move towards beneficial signals, such as nutrients, or away from harmful ones.

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