Lifeboat Foundation

Cell culture is an essential in vitro experimental tool. An attempt to recapitulate the body in a dish, in two and three dimensions, it has provided the basis for decades of research and probably thousands of PhDs. When it goes wrong, however, whether through accident, infection, misidentification, cross-contamination or uncontrolled differentiation (for stem cells), it can be very stressful, especially in the case of longer-term experiments or when using hard-to-replace cell lines. Another important consideration is reproducibility, which is an acknowledged life sciences industry issue. A 2015 PLOS Biol ogy study, for example, reported in an analysis of previous studies that the prevalence of irreproducible research was over 50% – equivalent to USD $28 billion per year on irreproducible preclinical research.¹ Inconsistencies in cell culture approaches are a potential issue in this regard, as if cells are not maintained or used in a consistent way, or are contaminated with an infection (like mycoplasma), this can negatively impact results and make it more difficult to reproduce and/or accurately interpret data.

“Quality control (QC) is a key part of assuring the quality of outputs from any cell culture process, and is an essential part of assuring reproducibility of scientific quality in research as well as assurance of the quality and safety of cell culture-derived products,” comments Glyn N Stacey, International Stem Cell Banking Initiative, Cambridge, UK, and the Institute for Stem Cells and Regeneration and National Stem Cell Resource Centre, Chinese Academy of Sciences, Beijing, China. “These topics are currently very much in the minds of journal editors, research funders and regulators and are thus of crucial significance to researchers.”

This article will look at these different aspects of cell culture quality control and the types of protocols that can be implemented to help ensure reliable and reproducible results.

Australian company AMSL Aero is preparing to start flight tests on what it claims will be the world’s most efficient eVTOL design, and one of the most affordable. This box-wing beauty, the Vertiia, will travel up to 1,000 km (620 miles) on a tank of hydrogen, carrying five people or 500 kg (1,100 lb) of cargo at a quick cruise speed of 300 km/h (186 mph).

First emerging from stealth mode late last year, AMSL has a unique design, a prototype nearly ready to fly, and a target date of 2024 to get its aircraft certified and into production. Its small team has achieved an impressive amount on a shoestring budget, and it’s now raising another round of funding to finance flight testing and pre-production as it moves toward the certification process.

We spoke to co-founder Andrew Moore to learn more about this fascinating aircraft, and how Vertiia plans to stand out in a global emerging eVTOL air taxi market that’s starting to look comically crowded. What follows is an edited transcript.

Over the past few years, the business world has increasingly turned towards intelligent solutions to help cope with the changing digital landscape. Artificial intelligence (AI) enables devices and things to perceive, reason and act intuitively—mimicking the human brain, without being hindered by human subjectivity, ego and routine interruptions. The technology has the potential to greatly expand our capabilities, bringing added speed, efficiency and precision for tasks both complex and mundane.

To get a picture of the momentum behind AI, the global artificial intelligence market was valued at $62.35 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 40.2% from 2021 to 2028. Given this projection, it’s not surprising that tech giants such as AWS, IBM, Google and Qualcomm have all made significant investments into AI research, development, disparate impact testing and auditing.

My coverage area of expertise, fintech (financial technology), is no exception to this trend. The AI market for fintech alone is valued at an estimated $8 Billion and is projected to reach upwards of $27 Billion in the next five years. AI and machine learning (ML) have penetrated almost every facet of the space, from customer-facing functions to back-end processes. Let’s take a closer look at these changing dynamics.

Fijitsu retrofitted one of it’s clean rooms in a vertical farm. The project was so successful, they discovered they could enter a new market segment and sell the systems themselves. I definately want one.

Like the giant monolith in Stanley Kubrick’s 2,001 this new head of lettuce is simultaneously a product of this factory’s past and the future. Fujitsu is a space-age R&D innovator with sprawling, specialized factories. But several of its facilities, including this one, went dark when the company tightened its belt and reorganized its product lines after the 2008 global financial crisis. Now in the aftermath, it has retrofitted this facilities to serve tomorrow’s vegetable consumers, who will pay for a better-than-organic product, and who enjoy a bowl of iceberg more if they know it was monitored by thousands of little sensors.

Like the giant monolith in Stanley Kubrick’s 2001, this new head of lettuce is simultaneously a product of this factory’s past and the future. Fujitsu is a space-age R&D innovator with sprawling, specialized factories. But several of its facilities, including this one, went dark when the company tightened its belt and reorganized its product lines after the 2008 global financial crisis. Now in the aftermath, it has retrofitted this facilities to serve tomorrow’s vegetable consumers, who will pay for a better-than-organic product, and who enjoy a bowl of iceberg more if they know it was monitored by thousands of little sensors.

Continue reading “Hydroponics made Fujitsu” »

One form of “self-sacrifice” was to stand on the banks of the Nile and masturbate into the river as offering to honour Lord Amen (this sacred act was how Amen, Cyclical Eternity, came into being originally). Lots of the neurosis around today are because of the biblical view of “onanism” The term “Onanism” is associated with personal indulgence, or excess (even mortal sin for Catholics) perhaps giving rise to infantilised and repressed sexuality and a PANDEMIC of Christian paedophilia. 216,000 children — shouldn’t the Church in France be closed down?

The Church asks for forgiveness as an inquiry says it treated victims with “cruel indifference”.

Yahoo Finance’s Ines Ferre reports on LinkedIn shutting down its app in China with plans to launch a jobs-only platform later this year.
Don’t Miss: Valley of Hype: The Culture That Built Elizabeth Holmes.
WATCH HERE:

Watch the 2021 Berkshire Hathaway Annual Shareholders Meeting on YouTube:
https://youtu.be/gx-OzwHpM9k.

Continue reading “LinkedIn shutting down in China due to censorship controversy” »

Many people reject scientific expertise and prefer ideology to facts. Lee McIntyre argues that anyone can and should fight back against science deniers.
Watch the Q&A: https://youtu.be/2jTiXCLzMv4
Lee’s book “How to Talk to a Science Denier” is out now: https://geni.us/leemcintyre.

“Climate change is a hoax—and so is coronavirus.” “Vaccines are bad for you.” Many people may believe such statements, but how can scientists and informed citizens convince these ‘science deniers’ that their beliefs are mistaken?

Continue reading “How to Talk to a Science Denier — with Lee McIntyre” »

Using AI to analyze your income and expenses regularly is a great way to help you better understand where your money goes each month. Most modern financial institutions have apps that will automatically categorize your spending into expense types, making it easy for you to see how much of your paycheck ends up going toward rent/mortgage, food, transportation, entertainment, etc.

Technology is empowering women to build wealth through AI-assisted financial management. Women are now able to invest and manage their finances by using technology that automatically invests and manages money for them. This software provides a unique algorithm for each woman with personalized goals, risk tolerance, income, and age.

Full Story:

Continue reading “Can Artificial Intelligence Help To Close The Financial Equality Gap For Women?” »

The U.S. Treasury Department’s Financial Crimes Enforcement Network (FinCEN) has identified roughly $5.2 billion worth of outgoing Bitcoin transactions likely tied to the top 10 most commonly reported ransomware variants.

FinCEN identified 177 CVC (convertible virtual currency) wallet addresses used for ransomware-related payments after analyzing 2,184 SARs (Suspicious Activity Reports) filed between January 1 2011, and June 30 2021, and reflecting $1.56 billion in suspicious activity.

Based on blockchain analysis of transactions tied to the 177 CVC wallets, FinCEN identified roughly $5.2 billion in outgoing BTC transactions potentially tied to ransomware payments.