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Here’s something I think you’ll find quite interesting… These crazy images were created by French artist Jean-Marc Cote, and a few others back in 1899, 1900, 1901, and 1910.

The point being… Well, basically they were asked to imagine what life would be like in the year 2000. According to Collective-Evolution, these artworks were originally in the form of postcards or paper cards enclosed in cigarette and cigar boxes.

The images depict the world as it was imagined it would be like in the year 2000. Some of these unique illustrations are actually quite accurate vision of the current era today, including farming machines, robotic equipment, and flying machines. Now we haven’t started riding giant seahorses yet, although it does look like one hell of a good time.

Dr. Susan White and her genetics team treated two triplets from a family who had an undiagnosed neurodegenerative disorder in 2014. After one year of age, the children’s developmental skills declined. They lost visual coordination. Feeding and swallowing food became impossible. The children developed intractable seizures.

Exactly what led to their neurodegeneration was a mystery.

“As you can imagine, that was just a horrendous experience for their family and we suspected a genetic condition because of that pattern of problems occurring in both children,” White, an associate professor at Murdoch Children’s Research Institute (MCRI) and Victorian Clinical Genetics Services (VCGS), said in an interview with Being Patient.

Defining our “New Normal” in the Age of Coronavirus — Amanda Christensen, ideaXme (http://radioideaxme.com/) guest interviewer, interviews Ben Hammersley, one of the world’s leading futurists to answer questions about how we are going to work, live, thrive, and innovate in the coming years — #Ideaxme #BenHammersley #Innovation #Futurist #Futurism #Covid19 #Coronavirus #Science #Longevity #Health #Medicine #Environment #Space #Oceans #Literature #Music #Food #Future #Entertainment #Sports #Fashion Awesome Foundation European University Institute United Nations Alliance of Civilizations (UNAOC) UNAOC Fellowship Program Goldsmiths, University of London WIRED UK The Brookings Institution European Commission.


Amanda Christensen, ideaXme guest interviewer, interviews Ben Hammersley, one of the world’s leading futurists and founder of international Strategic Foresight agency Hammersley Futures.

Amanda Christensen Comments:

Our world as we know it has seemingly changed overnight as countries globally make the decision to impose lockdown-type mandates in a worldwide effort to slow the spread of the deadly coronavirus (Covid-19).

As statistics, mandates, stocks, and all information related to coronavirus changes minute by minute, it can be overwhelming to keep up with it all, let alone separate fact from fiction, with misinformation being spread just as rapidly as the virus itself.

Amazon, the e-commerce giant that has fared well financially amid the COVID-19 pandemic, is facing a bevy of worker strikes. Today, warehouse workers on Staten Island in New York walked off the job in protest of Amazon’s treatment amid the crisis.

#BREAKING: Over 100 Amazon employees at JFK8 warehouse walk off the job over @amazon’s dangerous response to protect workers from COVID19 in Staten Island.

📦 #AmazonStrike #WhatWeNeed pic.twitter.com/z0mrUWmPfw

Circa 2017


Plant viruses, the simple obligate intracellular parasites with small genomes, rely entirely on host machineries for their life cycle including replication, intracellular (cell-to-cell) and systemic movement (Nelson and Citovsky, ). Virus infections pose serious threats to agriculture and cause huge economic losses. Despite encoding only a limited number of proteins, numerous interactions of viral RNAs/proteins with host factors have puzzled the plant virologists for over a century and the complexity of these interactions is just becoming understood.

Plants have developed two major strategies to counteract virus infections: resistance (R) gene-mediated, and RNA silencing-based defenses. In addition, the mutation in essential genes for viral infection also causes plant resistance against viruses, called recessive gene-mediated resistance. These approaches have been used in crop protections and have shown significant economic impact (Abel et al., ; Whitham et al., ; Baulcombe, ; Kang et al., ; Wang and Krishnaswamy, ).

This Research Topic combines 13 publications, including 9 review articles and 4 research articles, covering almost every aspect of plant-virus interactions. The featured in-depth topic reviews in various sub-fields provide readers a convenient way to understand the current status of the related sub-fields and the featured research articles expand the current knowledge in related sub-fields.

Most simply, the phrase “genome editing” represents tools and techniques that biotechnologists use to edit the genome — that is, the DNA or RNA of plants, animals, and bacteria. Though the earliest versions of genome editing technology have existed for decades, the introduction of CRISPR in 2013 “brought major improvements to the speed, cost, accuracy, and efficiency of genome editing.”

CRISPR, or Clustered Regularly Interspersed Short Palindromic Repeats, is actually an ancient mechanism used by bacteria to remove viruses from their DNA. In the lab, researchers have discovered they can replicate this process by creating a synthetic RNA strand that matches a target DNA sequence in an organism’s genome. The RNA strand, known as a “guide RNA,” is attached to an enzyme that can cut DNA. After the guide RNA locates the targeted DNA sequence, the enzyme cuts the genome at this location. DNA can then be removed, and new DNA can be added. CRISPR has quickly become a powerful tool for editing genomes, with research taking place in a broad range of plants and animals, including humans.

A significant percentage of genome editing research focuses on eliminating genetic diseases. However, with tools like CRISPR, it also becomes possible to alter a pathogen’s DNA to make it more virulent and more contagious. Other potential uses include the creation of “‘killer mosquitos,’ plagues that wipe out staple crops, or even a virus that snips at people’s DNA.”

Our body’s ability to detect disease, foreign material, and the location of food sources and toxins is all determined by a cocktail of chemicals that surround our cells, as well as our cells’ ability to ‘read’ these chemicals. Cells are highly sensitive. In fact, our immune system can be triggered by the presence of just one foreign molecule or ion. Yet researchers don’t know how cells achieve this level of sensitivity.

Now, scientists at the Biological Physics Theory Unit at Okinawa Institute of Science and Technology Graduate University (OIST) and collaborators at City University of New York have created a simple model that is providing some answers. They have used this model to determine which techniques a cell might employ to increase its sensitivity in different circumstances, shedding light on how the biochemical networks in our bodies operate.

“This model takes a complex biological system and abstracts it into a simple, understandable mathematical framework,” said Dr. Vudtiwat Ngampruetikorn, former postdoctoral researcher at OIST and the first author of the research paper, which was published in Nature Communications. “We can use it to tease apart how cells might choose to spend their energy budget, depending on the world around them and other cells they might be talking to.”

By bringing a quantitative toolkit to this biological question, the scientists found that they had a different perspective to the biologists. “The two disciplines are complimentary to one another,” said Professor Greg Stephens, who runs the unit. “Biologists tend to focus on one area and delve deeply into the details, whereas physicists simplify and look for patterns across entire systems. It’s important that we work closely together to make sure that our quantitative models aren’t too abstract and include the important details.”

On their computers, the scientists created the model that represented a cell. The cell had two sensors (or information processing units), which responded to the environment outside the cell. The sensors could either be bound to a molecule or ion from the outside, or unbound. When the number of molecules or ions in chemical cocktail outside the cell changed, the sensors would respond and, depending on these changes, either bind to a new molecule or ion, or unbind. This allowed the cell to gain information about the outside world and thus allowed the scientists to measure what could impact its sensitivity.

“Once we had the model, we could test all sorts of questions,” said Dr. Ngampruetikorn, “For example, is the cell more sensitive if we allow it to consume more energy? Or if we allow the two sensors to cooperate? How does the cell’s prior experiences influence its sensitivity?”

The scientists looked at whether allowing the cell to consume energy and allowing the two sensors to interact helped the cell achieve a higher level of sensitivity. They also decided to vary two other components to see if this had an impact—the level of noise, which refers to the amount of uncertainty or unnecessary information in the chemical cocktail, and the signal prior, which refers to the cell’s acquired knowledge, gained from past experiences.

The 43-year-old scientist is a member of the Technion’s Wolfson Faculty of Chemical Engineering, and his lab first developed a food additive to boost the immune system of animals to protect them from contracting viral diseases. This invention formed the basis of his own commercialized start-up company, ViAqua Therapeutics, which focused the development of the drug on shrimp, as over 30% of the global shrimp population is wiped out yearly by a viral disease known as white spot syndrome.


Israeli scientist and entrepreneur Prof. Avi Schroeder is working on a preventative drug for the coronavirus by adapting a food additive designed for shrimp.

The project is one of the several emergency projects that are the focus of around-the-clock work by 20 different labs at the Technion Institute of Technology to work on coronavirus vaccines, therapeutic treatments, diagnostic methods and patient treatment methods.

:ooooo.


Unlocking the full potential of cannabis for agriculture and human health will require a co-ordinated scientific effort to assemble and map the cannabis genome, says a just-published international study led by University of Saskatchewan researchers.

In a major statistical analysis of existing data and studies published in the Annual Review of Plant Biology, the authors conclude there are large gaps in the scientific knowledge of this high-demand, multi-purpose crop.

“Considering the importance of genomics in the development of any crop, this analysis underlines the need for a co-ordinated effort to quantify the genetic and biochemical diversity of this species,” the authors state.