Lifeboat Foundation: Safeguarding Humanity
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Category: food – Page 313

The Broad Institute in Cambridge, Mass., will retain potentially lucrative rights to a powerful gene-editing technique that could lead to major advances in medicine and agriculture, the federal Patent and Trademark Office ruled on Wednesday.

The decision, in a bitterly fought dispute closely watched by scientists and the biotechnology industry, was a blow to the University of California, often said to be the birthplace of the technique, which is known as Crispr-Cas9.

An appeals board of the patent office ruled that the gene-editing inventions claimed by the two institutions were separate and do not overlap.

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Humans won’t survive on Mars for very long if they don’t learn to grow their own food. That’s why we need to answer the question: What, if anything, can grow on the red planet?

A two-year experiment on the International Space Station (ISS) gives us some hints. A species of green algae and photosynthesizing bacteria have survived their 450-day stay in outer space. All but one of the algae samples started growing after being returned to Earth.

The experiment was part of the Biology and Mars Experiment (BIOMEX) to understand to what extent terrestrial life can survive in space. It involved a series of pockets where hundreds of specimens of bacteria, fungi, lichens, algae, and mosses were exposed to conditions of near vacuum, temperatures between −4 °F (−20 °C) and 116 °F (47 °C), and a continuous blast of ultraviolet radiation.

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In Brief

  • Researchers were able to increase the weight of tobacco plants by around 14 to 20 percent compared to unmodified plants by adding in genes to improve the process of photosynthesis.
  • If successful with other plants, the method could improve the yields of food crops such as cowpeas, rice, and cassava and decrease world hunger.

In terms of plants, the concept of genetically modified organisms (GMOs) often refers to the insertion of genetic information from one species of plant to another so that the recipient plant gains a desirable trait. This process has been used extensively to improve crop yields. For example, one type of rice has been made waterproof so that yields aren’t affected by heavy floods from typhoons.

Now, a group of researchers from the University of California, Berkeley, has published a paper in the journal Science that takes a different approach to increasing crop yields. Instead of inserting genetic information from one species of plant into another to change it, these biologists used genetic modification to tweak a mechanism already inherent in plants.

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Interesting read on recent Gastric Cancer research. I do a lot of work with the National Esophageal Cancer (EC) Awareness Association; I can tell you that this disease is truly a killer as gastric related cancers are horrible to detect early enough and have a horrible record of reoccurring. Survival rates are some of the worst and today the rates of EC have skyrocketed especially in the younger age groups such as 25 to 35 year olds.

When you work for these foundations, read the stories from patients and their families looking for answers and help with everything from help on what types of food can their love eat and hopefully keep down for nutrition, to how can they get help with transportation to simply go to work or the doctor as meds restrictions on driving, to knowing the end is near and how to prepare, etc. The worst ones are the 27 to 36 yr old fathers and mothers whose love one is saying good bye to the person they married only recently married the year before or spent 7 years with. This is why I work for my foundations as every small step does in the end create a larger impact in the end and hopefully helps us finally beat this disease.

STING (stimulator of interferon genes) has recently been found to play an important role in host defenses against virus and intracellular bacteria via the regulation of type-I IFN signaling and innate immunity. Chronic infection with Helicobacter pylori is identified as the strongest risk factor for gastric cancer. Thus, we aim to explore the function of STING signaling in the development of gastric cancer. Immunohistochemistry was used to detect STING expression in 217 gastric cancer patients who underwent surgical resection. STING protein expression was remarkably decreased in tumor tissues compared to non-tumor tissues, and low STING staining intensity was positively correlated with tumor size, tumor invasion depth, lymph mode metastasis, TNM stage, and reduced patients’ survival. Multivariate analysis identified STING as an independent prognostic factor, which could improve the predictive accuracy for overall survival when incorporated into TNM staging system. In vitro studies revealed that knock-down of STING promoted colony formation, viability, migration and invasion of gastric cancer cells, and also led to a defect in cytosolic DNA sensing. Besides, chronic H. pylori infection up-regulated STING expression and activated STING signaling in mice. In conclusion, STING was proposed as a novel independent prognostic factor and potential immunotherapeutic target for gastric cancer.

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We will need a good dose of healthy stoicism if we are to survive in the world after work. Luxury items will be significantly reduced in the world we’re imagining. Stoics like Marcus Aurelius and Seneca recommended that we adjust our desires to simple, reliable pleasures, like fresh water, decent bread, modest clothing, and good friends. Luxury pleasures are rare and unreliable so we suffer more when they fail to materialize.

But chocolate cake is delicious and diamonds are beautiful. When Plato sketched a Spartan lifestyle in the Republic, his friends accused him of designing a city for pigs not humans — and they demanded that he add spices and luxury to the imagined utopia. While I’m sensitive to this worry, I hasten to point out that many Americans are currently, and by their own initiative, downsizing their sense of the good life. The contemporary “tiny house movement” — which builds elegant housing around 1/10th the size of average homes — is already the kind of stoic adjustment that Americans will need to make when we’re all unemployed.

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