Construction work on this segment of the multibillion-dollar project is expected to run through 2029.

This could be the way we stay biologically younger in the future.

Zhang et al. reveal that Lactobacillus del brueckii ameliorates ulcerative colitis by suppressing proinflammatory macrophages via its surface protein, P4430. This mechanism, which involves targeting the host Mincle receptor, defines a microbial strategy for combating intestinal inflammation and suggests a potential therapeutic path.

Microsoft announced today that the Exchange Web Services (EWS) API for Exchange Online will be shut down in April 2027, after nearly 20 years.

EWS is a cross-platform API for developing apps that can access Exchange mailbox items, such as email messages, meetings, and contacts, retrieved from various sources, including Exchange Online and on-premises editions of Exchange (starting with Exchange Server 2007).

Microsoft will begin blocking Exchange Online EWS by default on October 1, 2026, but administrators can temporarily maintain access via an application allowlist. The final shutdown occurs on April 1, 2027, with no exceptions granted.

A researcher and company founder discusses how his interest in optofluidics led him to both academia and entrepreneurship.

Luan et al. identify the cullin-3 adaptor SHKBP1 as a noncanonical regulator of p62 phase behavior that limits p62 body formation, restrains Keap1 sequestr

Ancient duplicated genes are giving scientists their first real clues about what life was like before all life on Earth shared a common ancestor.

Cloud logs can be inconsistent or incomplete, creating blind spots as environments scale and change. Corelight shows how network-level telemetry provides reliable visibility when cloud logs fall short.