Lifeboat Foundation

The results pointed to MC1R, known previously as a gene for red hair and freckles.

Scientists say they have made a leap in knowing why some people retain their youthful looks while others age badly.

The new study is the first time that “a gene has been found that explains, in part, why some people look older and others younger for their age”, Manfred Kayser, a professor of forensic molecular genetics at Erasmus MC University Medical Center Rotterdam in the Netherlands and a senior author on the study, said in a statement.

Continue reading “Long in the tooth, or just a redhead?” »

There’s a precision genetic tool being put to work in crop breeding that offers benefits for future elite, high-performing crops. Pioneer is moving forward with work on a commercial hybrid.

With CRISPR-Cas it’s possible to do precision gene insertions (or deletions) in a crop genome that boost productivity or enhance other traits. This isn’t a GMO because the work done involves traits from the same species — corn gene into a corn plant, for example.

Continue reading “New genetic tools to boost productivity” »

“[Using DNA,] you could fit all the knowledge in the whole world inside the trunk of your car,” Twist Bioscience CEO Emily Leproust told TechCrunch.

Twist Bioscience, a startup making and using synthetic DNA to store digital data, just struck a contract with Microsoft and the University of Washington to encode vast amounts of information on synthetic genes.

Big data means business and the company able to gather a lot of it is very valuable to investors and stockholders. But that data needs to be stored somewhere and can cost a lot for the upkeep.

Continue reading “Genetics startup Twist Bioscience is working with Microsoft to store the world’s data in DNA” »

We definitely need precision medicine. If you don’t believe it is worth that; then I have a few widows & widowers who you should speak to; I have parents that you should speak with; I have a list of sisters & brothers that you should speak with; and I have many many friends (including me) that you should speak with about how we miss those we love because things like precision medicine wasn’t available and could have saved their lives.

Precision medicine is the theme for the 10th annual symposium of the Johns Hopkins Institute for Nano Biotechnology, Friday, April 29, 2016 at 9 a.m. in the Owens Auditorium at the School of Medicine. This year’s event is cohosted by Johns Hopkins Individualized Health Initiative (also known as Hopkins in Health) and features several in Health affiliated speakers.

By developing treatments that overcome the limitations of the one-size-fits-all mindset, precision medicine will more effectively prevent and thwart disease. Driven by data provided from sources such as electronic medical records, public health investigations, clinical studies, and from patients themselves through new point-of-care assays, wearable sensors and smartphone apps, precision medicine will become the gold standard of care in the not-so-distant future. Before long, we will be able to treat and also prevent diseases such as diabetes, Alzheimer’s disease, heart disease, and cancer with regimes that are tailor-made for the individual.

Continue reading “Why precision medicine is important for our future” »

My new Vice Motherboard article on environmentalism and why going green isn’t enough. Only radical technology can restore the world to a pristine condition—and that requires politicians not afraid of the future:

I’m worried that conservatives like Cruz will try to stop new technologies that will change our battle in combating a degrading Earth

But there are people who can save the endangered species on the planet. And they will soon dramatically change the nature of animal protection. Those people may have little to do with wildlife, but their genetics work holds the answer to stable animal population levels in the wild. In as little as five years, we may begin stocking endangered wildlife in places where poachers have hunted animals to extinction. We’ll do this like we stock trout streams in America. Why spend resources in a losing battle to save endangered wildlife from being poached when you can spend the same amount to boost animal population levels ten-fold? Maye even 100-fold. This type of thinking is especially important in our oceans, which we’ve bloody well fished to near death.

Continue reading “If You Care About the Earth, Vote for the Least Religious Presidential Candidate” »

Nano-particles to treat Acute Myeloid Leukaemia.

A new therapeutic strategy for treating Acute Myeloid Leukaemia could involve using nano-particles to deliver a genetic molecule to fight the disease.

The nanoparticles carrying microRNA miR-22, (a small non-coding RNA molecule that regulates gene expression), showed therapeutic potential in mouse models of Acute Myeloid Leukemia (AML).

Continue reading “Nanoparticles may help treat blood cancer” »

Lesson in Vitamin D.

Low levels of vitamin D in black teens correlates with low activity of a major mechanism for controlling gene expression that may increase their risk of cancer and other disease, researchers report.

Their study measured vitamin D levels as well as levels of global DNA methylation in 454 healthy individuals age 14–18. In this group, 99 percent of the white teens had adequate vitamin D levels, 66 percent of the black teens were vitamin D-deficient and all the black teens had lower levels of methylation compared to their white peers, said Dr. Haidong Zhu, molecular geneticist at the Georgia Prevention Institute at the Medical College of Georgia at Augusta University.

Continue reading “Low levels of vitamin D, methylation in black teens may increase cancer risk” »

BOSTON: In an intriguing approach to the fight against cancer, researchers for the first time have used light to prevent and reverse tumors using a technique called optogenetics to manipulate electrical signaling in cells.

Scientists at Tufts University performed optogenetics experiments on frogs, often used in basic research into cancer because of the biological similarities in their tumors to those in mammals, to test whether this method already used in brain and nervous system research could be applied to cancer.

“We call this whole research program cracking the bioelectric code,” said biologist Michael Levin, who heads the Tufts Center for Regenerative and Developmental Biology.

Continue reading “Researchers use light to battle cancer” »

Hmmm; I do know for many there is a set of genetic mutations that seem to sit dormat and eventually triggered by environment conditions.

(Reuters Health) — The risk of some childhood cancers might vary depending on where a child’s mother was born, a new study suggests.

For example, some brain and kidney cancers occurred less often in children whose Hispanic mothers were born outside the U.S. than in youngsters whose Hispanic or white mothers were born in the U.S., researchers found.

Continue reading “Kids’ cancer risk might be tied to where mom was born” »