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MANILA, Philippines — A Filipino startup is recognized globally in developing a dengue hotspot prediction system using satellite and climate data in the 2020 Group on Earth Observations Sustainable Development Goals (GEO SDG) Awards for the Sectoral category, For-Profit. The GEO SDG Awards recognize the productivity, ingenuity, proficiency, novelty, and exemplary communications of results and experiences in the use of Earth observations to support sustainable development.

CirroLytix Research Services was formed to create social impact through big data. Through the application of machine learning, data engineering, remote sensing, and social listening, the Philippines-based data analytics firm hopes to help governments, researchers, non-government organizations (NGO), and social enterprises achieve positive change. The Advanced Early Dengue Prediction and Exploration Service (Project AEDES) is one of the CirroLytix’s flagship projects developed during the 2019 National Aeronautics and Space Administration’s (NASA) International Space Apps Challenge. It combines digital, climate, and remote sensing to nowcast dengue trends and detect mosquito habitats to help pre-empt cases of dengue. Project AEDES process leverages normalized difference vegetation index (NDVI), Fraction of absorbed photosynthetically active radiation (FAPAR), and normalized difference water index (NDWI) readings from Landsat and Sentinel-2 to estimate still water areas on the ground, which is correlated with dengue case counts from national health centers.

Dominic Vincent “Doc” Ligot, co-founder and chief technology officer of CirroLytix, describes Project AEDES as an “early detection of panics from online searches, anticipating case counts from environment readings, but most importantly pinpointing hotspots from mosquito habitat detection.”

The Pinoy-made dengue mapper tool won the annual international hackathon of NASA globally in the best use of data, the solution that best makes space data accessible, or leverages it to a unique application. Aside from winning last year, CirroLytix also developed an integrated public policy information portal measuring the impact of the coronavirus pandemic using Earth observation, in-country economic and human mobility data, and global infection case counts, thus winning again in the Space Apps COVID-19 Challenge for the same category in the best use of data. Named G.I.D.E.O.N. (Global Impact Detection from Emitted Light, Onset of COVID-19, and Nitrogen Dioxide), this dashboard for policy makers and economic planners shows the impact of COVID-19 on various countries and effects on the economy and environment.

Continue reading “Filipino startup recognized in addressing SDG's using space tech” »

Rusted iron pipes can react with residual disinfectants in drinking water distribution systems to produce carcinogenic hexavalent chromium in drinking water, reports a study by engineers at UC Riverside.

Chromium is a metal that occurs naturally in the soil and groundwater. Trace amounts of trivalent chromium eventually appear in the drinking water and food supply and are thought to have neutral effects on health. Chromium is often added to iron to make it more resistant to corrosion.

Certain chemical reactions can change chromium atoms into a hexavalent form that creates cancer-causing genetic mutations in cells. This carcinogenic form of chromium was at the heart of a lawsuit in California’s Central Valley by Erin Brockovich, which became the subject of an Oscar-winning movie.

ANCHORAGE, Alaska (Reuters) — A Fairbanks clinician suffered anaphylactic symptoms after being given the Pfizer Inc coronavirus vaccine, a hospital said on Friday, becoming the third Alaska health care worker to suffer an adverse reaction to the new drug. The clinician, whose name was not released, started showing symptoms about 10 minutes after being inoculated on Thursday, according to Foundation Health Partners, operator of the Fairbanks Memorial Hospital. The health care worker was treated in the hospital’s emergency room with epinephrine and released about six hours later, Foundation Health Partners said in a written statement. “Allergic reactions, though uncommon, can occur with injections of medications and vaccines,” Foundation Health Partners’ Chief Medical Officer Dr. Angelique Ramirez said in the statement.

“A reactogenic vaccine is not the same thing as an unsafe vaccine,” says Saad Omer, a vaccinologist and the director of the Yale Institute for Global Health.”

The COVID-19 vaccine will make some people feel sick. But they’re not—that’s the immune system doing its job.

As we sit here in 2020, in the middle of a major viral pandemic, we can’t forget the fact that a century after the first antibiotics were created, drug resistant bacterial infections have become a major threat around the globe, exactly at the same time that the antibiotic pipelines of pharma companies have either dried up, or they have gotten out of the business.

In the U.S. alone, Centers For Disease Control (CDC) estimates that antibiotic resistance causes more than 2 million infections, several million hospital stay days, and over 35, 000 deaths per year. Worldwide, such infections cause 750, 000 deaths every year. And a recent United Nations (UN) report concluded that by 2050, “super bugs” could kill 10 million people globally every year, if no action is taken to combat the problem.

Continue reading “Dr. Robert Schooley MD — Harnessing Phage Therapies In The Fight Against Drug Resistant ‘Super-Bugs’” »

Emerging and reemerging infections present an ever-increasing challenge to global health. Here, we report a nanoparticle-enabled smartphone (NES) system for rapid and sensitive virus detection. The virus is captured on a microchip and labeled with specifically designed platinum nanoprobes to induce gas bubble formation in the presence of hydrogen peroxide. The formed bubbles are controlled to make distinct visual patterns, allowing simple and sensitive virus detection using a convolutional neural network (CNN)-enabled smartphone system and without using any optical hardware smartphone attachment. We evaluated the developed CNN-NES for testing viruses such as hepatitis B virus (HBV), HCV, and Zika virus (ZIKV). The CNN-NES was tested with 134 ZIKV-and HBV-spiked and ZIKV-and HCV-infected patient plasma/serum samples. The sensitivity of the system in qualitatively detecting viral-infected samples with a clinically relevant virus concentration threshold of 250 copies/ml was 98.97% with a confidence interval of 94.39 to 99.97%.

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Smartphone systems can also benefit from the recent unprecedented advancements in nanotechnology to develop diagnostic approaches. Catalysis can be considered as one of the popular applications of nanoparticles because of their large surface-to-volume ratio and high surface energy (11–16). So far, numerous diagnostic platforms for cancer and infectious diseases have been developed by substituting enzymes, such as catalase, oxidase, and peroxidase with nanoparticle structures (17–20). Here, we adopted the intrinsic catalytic properties of platinum nanoparticles (PtNPs) for gas bubble formation to detect viruses on-chip using a convolutional neural network (CNN)–enabled smartphone system.

Johnson & Johnson said Thursday that late-stage clinical trials for its coronavirus vaccine are now fully enrolled, and expects to release initial data on the shot’s effectiveness by the end of January.

The pharmaceutical company’s single-dose vaccine is in Phase 3 clinical trials that are now fully enrolled, and is already being reviewed by Health Canada.

Mice, fruit flies and dogs are common creatures of laboratories across the country, valuable to researchers for their genetic proximity to humans. But what about lampreys?

A new Yale School of Public Health study has enlisted this unlikely and slimy ally in the fight against cancer.

By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are—and are not—effective in gauging how an analog of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not. Their findings, published in the journal Genome Biology and Evolution, will help molecular biologists and other scientists as they work to find potential cures to certain cancers, such as lymphoma.

Sony Corp. has created one of the hottest gadgets of the year in the PlayStation 5, but its launch has been marred by scalpers who are buying up scarce supplies and threatening the long-term health of the company’s most important product.