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It has long been understood that a parent’s DNA is the principal determinant of health and disease in offspring. Yet inheritance via DNA is only part of the story; a father’s lifestyle such as diet, being overweight and stress levels have been linked to health consequences for his offspring. This occurs through the epigenome—heritable biochemical marks associated with the DNA and proteins that bind it. But how the information is transmitted at fertilization along with the exact mechanisms and molecules in sperm that are involved in this process has been unclear until now.

A new study from McGill, published recently in Developmental Cell, has made a significant advance in the field by identifying how is transmitted by non-DNA molecules in the sperm. It is a discovery that advances scientific understanding of the heredity of paternal life experiences and potentially opens new avenues for studying disease transmission and prevention.

Sherpa, a startup from Bilbao, Spain that was an early mover in building a voice-based digital assistant and predictive search for Spanish-speaking audiences, has raised some more funding to double down on a newer focus for the startup: building out privacy-first AI services for enterprise customers.

The company has closed $8.5 million, funding that Xabi Uribe-Etxebarria, Sherpa’s founder and CEO, said it will be using to continue building out a privacy-focused machine learning platform based on a federated learning model alongside its existing conversational AI and search services. Early users of the service have included the Spanish public health services, which were using the platform to analyse information about COVID-19 cases to predict demand and capacity in emergency rooms around the country.

The funding is coming from Marcelo Gigliani, a managing partner at Apax Digital; Alex Cruz, the chairman of British Airways; and Spanish investment firms Mundi Ventures and Ekarpen. The funding is an extension to the $15 million Sherpa has already raised in a Series A. From what I understand, Sherpa is currently also raising a larger Series B.

Some experts have chimed in that tempering social distancing recommendations could be an important step to getting children back into classrooms. Dr. Ashish Jha, dean of the Brown University School of Public Health, suggested in a tweet that the C.D.C. guidance may be changing, and that is “good. Because 6 ft doesn’t protect teachers. But it does keep kids out of school.”

“Want to open schools safely? Masks. Ventilation. Testing. Vaccinating teachers/staff. That’s the list,” Dr. Jha tweeted.

The new study, published March 10, compared the incidence rates of coronavirus cases among students and staff in Massachusetts school districts that required at least six feet of separation with those that required only three feet of distance, and found no statistically significant differences in infection rates among staff members or students.

The Strait of Gibraltar is featured in this false-color image captured by the Copernicus Sentinel-2 mission on October 282020. Credit: Contains modified Copernicus Sentinel missions (2020), processed by ESA, CC BY-SA 3.0 IGO

The Strait of Gibraltar connects the Mediterranean Sea with the Atlantic Ocean and separates southernmost Spain from northernmost Africa. The channel is 58 km long and narrows to 13 km in width between Point Marroquí (Spain) and Point Cires (Morocco). Ferries and vessels can be seen traveling across the strait and crossing between the two continents.

This false-color image, captured on October 282020, was processed in a way that included the near-infrared channel. This type of band combination from Copernicus Sentinel-2 is most commonly used to assess plant density and health, as plants reflect near-infrared and green light, while absorbing red. Since they reflect more near-infrared than green, dense, plant-covered land appears in bright red.

I didn’t get my 2nd Moderna Vaccine because how sick others became after theirs — nausea, fatigue, headaches for days, lymph nodes the size of a rock that fits in your hand, increased heart rate… Recently a Utah woman died 4 days after her 2nd vaccine-her heart, liver and kidneys failed. Less then a yr ago I read several studies on hospitalized COVID patients — how their kidneys and liver were failing. I read a recent study on how post COVID individuals are now having heart issues. Another study shows how COVID attacks the heart and why such individuals are now having heart issues. In December 2020, 13 individuals died after getting vaccinated (probably more since then). There is a real connection between COVID and organ failure!!!! I wish I kept links of all the information I read. Be happy to find them again. We don’t even know the long term affects of the vaccine — are the vaccinated going to experience long term health issues as well? Take your chances with a vaccine, or not.

A Utah woman in her 30s died four days after receiving the coronavirus vaccine.

Kassidi Kurill, 39, was healthy and happy and “had more energy” than others, according to a KUTV report. Then, four days after she received her second dose of the coronavirus vaccine, she suddenly died.

“She came in early and said her heart was racing and she felt like she [needed] to get to the emergency room,” her family said. Her father, Alfred Hawley, said he woke up to her asking for help.

Saving Lives; Changing Minds — Dr. Emanuele Capobianco, MD, Director for Health and Care, International Federation of Red Cross and Red Crescent Societies.


Dr. Emanuele Capobianco, MD, MPH, is the Director for Health and Care at the International Federation of Red Cross and Red Crescent Societies (IFRC), where he leads the IFRC Global Health and Care Team and provides strategic and operational support to 192 National Red Cross and Red Crescent Societies around the world in the areas of community health, emergency health and water/sanitation. He currently also leads the IFRC global response to COVID19 and the IFRC response to the Ebola outbreaks in DRC.

Before this role at IFRC, Dr. Capobianco was the Deputy Executive-Director of The Partnership for Maternal, Newborn & Child Health, a multi-constituency partnership, hosted by the World Health Organization, and is the world’s largest alliance for women’s, children’s and adolescents’ health. He joined there from the Global Fund to Fight AIDS, Tuberculosis and Malaria where he worked as Senior Policy Advisor in the Office of the Executive Director, leading the development of the 2017–2022 Global Fund Strategy.

Dr. Capobianco is a global public health expert with 20 years experience in international institutions at country, regional and headquarters level. He was the Chief of Health and Nutrition in UNICEF Mozambique, where he worked for four years to advance health outcomes for Mozambican children and women.

Previously Dr. Capobianco was at the World Bank as Senior Health Specialist, managing a large portfolio of grants, particularly in South Asia and Eastern Africa. He also worked in Somalia to support the Expanded Program on Immunization, Polio and Tuberculosis programs; and at the WHO Regional Office for the Eastern Mediterranean promoting the STOP TB partnership in the Middle East.

As the world fights the SARS-CoV-2 virus causing the COVID-19 pandemic, another group of dangerous pathogens looms in the background. The threat of antibiotic-resistant bacteria has been growing for years and appears to be getting worse. If COVID-19 taught us one thing, it’s that governments should be prepared for more global public health crises, and that includes finding new ways to combat rogue bacteria that are becoming resistant to commonly used drugs.

In contrast to the current pandemic, viruses may be be the heroes of the next epidemic rather than the villains. Scientists have shown that viruses could be great weapons against bacteria that are resistant to antibiotics.

I am a biotechnology and policy expert focused on understanding how personal genetic and biological information can improve human health. Every person interacts intimately with a unique assortment of viruses and bacteria, and by deciphering these complex relationships we can better treat infectious diseases caused by antibiotic-resistant bacteria.

North Carolina State University engineers continue to improve the efficiency of a flexible device worn on the wrist that harvests heat energy from the human body to monitor health.

In a paper published in npj Flexible Electronics, the NC State researchers report significant enhancements in preventing leakage in the flexible body heat harvester they first reported in 2017 and updated in 2020. The harvesters use from the human body to power —think of smart watches that measure your heart rate, blood oxygen, glucose and other health parameters—that never need to have their batteries recharged. The technology relies on the same principles governing rigid thermoelectric harvesters that convert heat to .

Flexible harvesters that conform to the are highly desired for use with wearable technologies. Mehmet Ozturk, an NC State professor of electrical and computer engineering and the corresponding author of the paper, mentioned superior skin contact with , as well as the ergonomic and comfort considerations to the wearer, as the core reasons behind building flexible thermoelectric generators, or TEGs.

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

Now, in the first study of its kind, Cheryl Nickerson, lead author Jennifer Barrila and their colleagues describe the infection of by the intestinal pathogen Salmonella Typhimurium during . They show how the microgravity environment of spaceflight changes the molecular profile of human intestinal and how these expression patterns are further changed in response to infection. In another first, the researchers were also able to detect in the bacterial pathogen while inside the infected host cells.

The results offer fresh insights into the infection process and may lead to novel methods for combatting invasive pathogens during spaceflight and under less exotic conditions here on earth.

While these tools will enable our society to reopen (and stay open) by improving detection of the virus, CRISPR will also have an important effect on the way we treat other diseases. In 2021, we will see increased use of CRISPR-Cas enzymes to underpin a new generation of cost-effective, individualised therapies. With CRISPR enzymes, we can cut DNA at precise locations, using specifically designed proteins, and insert or delete pieces of DNA to correct mutations.

As we deepen our understanding of the human genome and genetic disorders, patients with previously intractable diseases, such as sickle-cell disease and cancer, will benefit more widely from CRISPR-based therapies that are rapidly moving from the lab to the clinic. In 2019, sickle-cell patient Victoria Gray, for example, became one of the first patients in the world to receive CRISPR therapy for her genetic disease. She has already seen significant improvements to her health, including reduced pain and less frequent need for blood transfusions.

CRISPR will also allow us to act more boldly in the face of other important, interconnected issues such as food security, environmental sustainability and social inequality. The technology will help us grow more nutritious and robust crops, establish “gene drives” to control the spread of other infectious diseases such as Zika, and develop cleaner energy sources such as algae-based biofuels.