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Category: health – Page 265

Machine learning uncovers ‘genes of importance’ in agriculture and medicine

“We show that focusing on genes whose expression patterns are evolutionarily conserved across species enhances our ability to learn and predict ‘genes of importance’ to growth performance for staple crops, as well as disease outcomes in animals,” explained Gloria Coruzzi, Carroll & Milton Petrie Professor in NYU’s Department of Biology and Center for Genomics and Systems Biology and the paper’s senior author.

Machine learning can pinpoint “genes of importance” that help crops to grow with less fertilizer, according to a new study published in Nature Communications. It can also predict additional traits in plants and disease outcomes in animals, illustrating its applications beyond agriculture.

Using to predict outcomes in agriculture and medicine is both a promise and challenge for . Researchers have been working to determine how to best use the vast amount of genomic data available to predict how organisms respond to changes in nutrition, toxins, and pathogen exposure—which in turn would inform crop improvement, disease prognosis, epidemiology, and public health. However, accurately predicting such complex outcomes in agriculture and medicine from genome-scale information remains a significant challenge.

In the Nature Communications study, NYU researchers and collaborators in the U.S. and Taiwan tackled this challenge using machine learning, a type of artificial intelligence used to detect patterns in data.

Craig Fugate, Chief Emergency Management Officer, One Concern — Disaster Science, Digital Twins, AI

Disaster sciences, digital twins & artificial intelligence — craig fugate, chief emergency management officer, one concern.

Mr. Craig Fugate is the former Director of the Florida Division of Emergency Management, and former administrator of the Federal Emergency Management Agency (FEMA — an agency of the United States Department of Homeland Security, whose primary purpose is to coordinate the response to disasters that have occurred in the United States and that overwhelm the resources of local and state authorities.)

Mr. Fugate is currently the Chief Emergency Management Officer of One Concern, (a Resilience-as-a-Service solutions company that brings disaster science together with machine learning for better decision making).

Mr. Fugate is also senior advisor at BlueDot Strategies, where he assists a range of clients with emergency management implementation strategies and crisis communications.

Mr. Fugate serves on the Board of Directors of PG&E Corp., one of the largest electric and natural gas utilities in the U.S., and on the staff at Indian River State College, serving as a strategic consultant in emergency management.

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Bacteria Makes Contaminated Water Drinkable

Bacteria may get a bad reputation in general, yet it’s actually generally healthy and serves an important role in many habitats, including human bodies. From supporting life on Earth to being employed in industrial and medicinal processes, bacteria have their figurative fingers in many pots — some varieties of bacteria can even filter tainted water and make it safe for human consumption.

A team of researchers from the Indian Institute of Technology, Banaras Hindu University (IIT-BHU) has found a bacteria that can do just that — Named “microbacterium paraoxydans strain VSVM IIT (BHU)” by the scientists, it can separate toxic hexavalent chromium from water in an effective and eco-friendly manner, according to a research published in the Journal of Environmental Chemical Engineering.

Hexavalent chromium is a heavy metal ion that is used in electroplating, welding, and chromate painting, among other things. It’s said to be responsible for health problems in humans like cancers, kidney and liver malfunctioning, and infertility. When compared to current approaches, the scientists believe that this bacterial strain, which can tolerate high amounts of hexavalent chromium, is particularly successful at eliminating the harmful substance from wastewater.

Glow-in-the-dark plants could act as passive lighting for public spaces

A decent chunk of energy usage goes towards lighting, so scientists at MIT are developing a new kind of passive lighting – glow-in-the-dark plants. In the latest experiment, the team has made them glow much brighter than the first generation plants, without harming their health.

The emerging field of “plant nanobionics” involves embedding nanoparticles into plants to give them new abilities. Past work by the MIT team has created plants that can send electrical signals when they need water, spinach that could be used to detect explosives, and watercress that glows in the dark.

As interesting as that last one was, the glow wasn’t particularly bright – about on par with those plastic glowing stars many of us stuck to our ceilings as kids. That’s a cool novelty but not much help for the ultimate use case of passive lighting.

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Salty Diet Helps Gut Bugs Fight Cancer in Mice: Study

Amit Awasthi, an immunologist with the Translational Health Science and Technology Institute in India and corresponding author of the study, says he and his colleagues pursued this line of inquiry because previous research had linked high salt intake with autoimmune diseases, suggesting that increased salt stimulates immune cells. Meanwhile, tumors are well known to grow in immune-suppressive environments.

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In mice, a diet high in salt suppresses tumor growth—but only when gut microbes are there to stimulate immune cells, a September 10 study in Science Advances reports. The findings raise tantalizing questions about the role of diet and gut microbes in human cancers, and may point to new avenues for therapeutic development.

While the study isn’t the first to connect a high-salt diet to shrinking tumors, “[the authors] have shown a unique mechanistic role of high salt induced gut microbiome changes as the central phenomenon behind their observed anti-cancer effect,” writes Venkataswarup Tiriveedhi, a biologist at Tennessee State University who has studied the effect of salt on cancer progression but was not involved in the study, in an email to The Scientist.

Light-to-moderate coffee drinking associated with health benefits

This is for all who like coffee:

“To our knowledge, this is the largest study to systematically assess the cardiovascular effects of regular coffee consumption in a population without diagnosed heart disease,” said study author Dr. Judit Simon, of the Heart and Vascular Centre, Semmelweis University, Budapest, Hungary.

Our results suggest that regular coffee consumption is safe, as even high daily intake was not associated with adverse cardiovascular outcomes and all-cause… See More.

Your access to the latest cardiovascular news, science, tools and resources.

NASA Selects Five U.S. Companies — Including SpaceX and Blue Origin — for Artemis Lunar Lander Concepts

The selected companies will develop lander design concepts, evaluating their performance, design, construction standards, mission assurance requirements, interfaces, safety, crew health accommodations, and medical capabilities. The companies will also mitigate lunar lander risks by conducting critical component tests and advancing the maturity of key technologies.

The work from these companies will ultimately help shape the strategy and requirements for a future NASA’s solicitation to provide regular astronaut transportation from lunar orbit to the surface of the Moon.

Deep learning helps predict new drug combinations to fight COVID-19

The existential threat of COVID-19 has highlighted an acute need to develop working therapeutics against emerging health threats. One of the luxuries deep learning has afforded us is the ability to modify the landscape as it unfolds — so long as we can keep up with the viral threat, and access the right data.

As with all new medical maladies, oftentimes the data needs time to catch up, and the virus takes no time to slow down, posing a difficult challenge as it can quickly mutate and become resistant to existing drugs. This led scientists from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) to ask: how can we identify the right synergistic drug combinations for the rapidly spreading SARS-CoV-2?

Typically, data scientists use deep learning to pick out drug combinations with large existing datasets for things like cancer and cardiovascular disease, but, understandably, they can’t be used for new illnesses with limited data.

Civilian Space Development has kicked-off: the work starts now!

Civilian Space Development has kicked-off: the work begins now!

Newsletter 17.09.2021 by Bernard Foing & Adriano V. Autino

During the last months we have seen the first civilian passengers fly to space, onboard Blue Origin and Virgin Galactic vehicles. September 15th, four civilian astronauts, onboard a Space X Dragon capsule, passed the 500 km orbit, more than 100 km higher than the ISS.In 2016 we started to publicly talk about and promote Civilian Space Development, while the whole space community kept on talking only about space exploration. Earlier, in 2,008 we founded the Space Renaissance movement, and a couple of years later the Space Renaissance International, as a philosophical association targeted to complete the Kopernican Revolution, supporting the Civilization expansion into space. Nowadays the concept of civilian space flight is everywhere on the media, and many people in the space community talk about a space renaissance. Of course the Coronavirus pandemics accelerated the awareness of the urgency to expand humanity into outer space. And space tourism — the first stage of civilian space settlement — is now a reality, in its first steps.

Of course nobody could be more happy than ourselves, for the above development, and of course**2 we want to congratulate with Elon, Richard and Jeff, for such a great achievement!

So, may we consider that our mission has been completed? Let’s see.

Firstly, were those crews composed by regular travelers, like normal air-flight passengers? Not exactly. The Inspiration4 crew members received astronaut training, for many months, including lessons in orbital mechanics, operating in a microgravity, stress testing, emergency preparedness training, and mission simulations. They have studied over 90 different kinds of training guides and manuals and lessons to learn to fly Crew Dragon, and what to do under emergency situations. The legal aspects are not clear: did FAA quickly authorize Space X and Blue Origin to deal commercial space flights? Doubt is more than legitimate, considering the long procedure followed by Virgin Galactic to be authorized to transport paying passengers in space. Likely, these first “civilian” passengers — like the first orbital tourist Dennis Tito did in 2001 — accepted conditions similar to the military astronauts (i.e. zero rights and warrants).

Therefore, we cannot say that the first “civilians” has gone to space. Yes, they are not military, but (i) they needed a hard astronautic training and (ii) they don’t have the rights and warrants given by air-flight companies to their passengers. It means, basically, that the vehicles are still more suitable to transport astronauts means than civilian passengers.

A lot of work is still to be done, to allow civilians to travel, live and work in space. And the real implementation of such work depends mostly on the right political decisions, and from the support by public opinion. We still need to fight against the fake news, the opposers, the misconceptions, the so many apparently reasonable objections to human expansion into outer space.

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