Fighting Antibiotic Resistance By Repurposing Old Drugs : Shots — Health News Scientists discovered that a medication used to treat parasites in horses can fight deadly staph infections. It’s a promising new approach to solving the problem of antibiotic resistance.
Posted in health, law enforcement, neuroscience
This article appears in Weekly Health Page July 31.
Researchers found that more than four out of five Ohio women who had been physically abused by their partners had suffered a head injury. A study that found domestic violence survivors had sustained staggering rates of head trauma and violent choking incidents suggests that many are left with ongoing health problems from “invisible injuries” to the brain.
But the effects of such injuries often go unrecognized by advocates, health care providers, law enforcement — even the victims themselves, researchers said.
Living healthier and longer can depend on probiotics more than we ever thought.
The bacteria in our gut make thousands of tiny, previously unidentified proteins that could shed light on human health and advance drug development, Stanford researchers have found.
Posted in aging, bioengineering, biotech/medical, business, genetics, health, life extension, neuroscience, posthumanism, transhumanism | 1 Comment on Bill Faloon, Director / Co-Founder of Life Extension Foundation — ideaXme Show — Ira Pastor
“Over the past 50 years [America has] gone from institutionalizing people with mental illnesses, often in subhuman conditions, [in state mental health hospitals] to incarcerating them at unprecedented and appalling rates—putting recovery out of reach for millions of Americans […] On any given day, between 300,000 and 400,000 people with mental illnesses are incarcerated in jails and prisons across the United States, and more than 500,000 people with mental illnesses are under correctional control in the community.” [1] Mental Health America (MHA) supports effective, accessible mental health treatment for all people who need it who are confined in adult or juvenile correctional facilities or under correctional control. People with mental health and substance use conditions also need an effective classification system to protect vulnerable prisoners and preserve their human rights. [2] Notwithstanding their loss of their liberty, prisoners with mental health and substance use conditions retain all other rights, and these must be zealously defended.
Background
In the past decade, America has been locking up increasing numbers of individuals with mental health conditions. [3] MHA is both concerned by and opposed to the increasing use of criminal sanctions and incarceration, replacing the state mental hospitals with much more drastic curtailment of personal liberty and preclusion of community integration and community-based treatment. [4] Prisoners with mental health conditions are especially vulnerable to the difficult and sometimes deplorable conditions that prevail in jails, prisons, and other correctional facilities. Overcrowding often contributes to inadequacy of mental health services and to ineffective classification and separation of prisoner classes. It can both increase vulnerability and exacerbate mental illnesses. For these and other reasons, MHA supports maximum reasonable diversion. [5].
Prior studies in mice have shown that whole body vibration (WBV) can mimic some of the positive effects on health of exercise, and even reverse some of the symptoms of type 2 diabetes. New research by a team at the Medical College of Georgia (MCG) and Dental College of Georgia (DCG) at Augusta University has provided new clues as to the mechanisms involved. Their studies in a mouse model of obesity showed that WBV results in increased levels of inflammation-suppressing immune system macrophages, and high numbers of gut bacteria that makes short-chain fatty acids (SCFAs), which can help the body better utilize glucose.
The findings “… support the notion that WBV has the potential to alter the microbiota in a way that triggers innate and mucosal immunity to produce anti-inflammatory responses, down-regulating the hyper-inflammatory state and reversing the adverse consequences,” the investigators wrote in their published paper in the International Journal of Molecular Sciences. “More studies are required to solidify this novel approach, which can be a very affordable and effective therapeutic modality in the prevention and treatment of many diseases, including diabetes and obesity.” The researchers, headed by Jack Yu, MD, chief of pediatric plastic surgery at MCG, and Babak Baban, PhD, immunologist and intern associate dean for research at DCG, reported their findings in a paper titled, “Whole Body Vibration-Induced Omental Macrophage Polarization and Fecal Microbiome Modification in a Murine Model.”
The combination of high-fat, sugar-heavy diets and “massively reduced physical activities” is largely responsible for what the researchers called “an epidemic of obesity and chronic metabolic diseases,” including type 2 diabetes. Chronic inflammation is a major contributory factor to the development of metabolic and cardiovascular diseases, and the immune system’s macrophages play a key role in regulating inflammatory responses.
Genetically Modified Bacteriophages Appear To Fight Off Resistant Bacteria : Shots — Health News Treatment with genetically altered bacteriophages — viruses that attack bacteria — may have halted a patient’s near-fatal infection, hinting at new ways to fight antibiotic-resistant bacteria.
Newly discovered life forms inside our bodies profoundly affect our health – and provide a glimpse of the vast and mysterious biological “dark matter” within us.
But critics point out that all that promise could vanish if the rush to implement A.I. tramples patient privacy rights, overlooks biases and limitations, or fails to deploy services in a way that improves health outcomes for most people.
You could be forgiven for thinking that A.I. will soon replace human physicians based on headlines such as “The A.I. Doctor Will See You Now,” “Your Future Doctor May Not Be Human,” and “This A.I. Just Beat Human Doctors on a Clinical Exam.” But experts say the reality is more of a collaboration than an ousting: Patients could soon find their lives partly in the hands of A.I. services working alongside human clinicians.
There is no shortage of optimism about A.I. in the medical community. But many also caution the hype surrounding A.I. has yet to be realized in real clinical settings. There are also different visions for how A.I. services could make the biggest impact. And it’s still unclear whether A.I. will improve the lives of patients or just the bottom line for Silicon Valley companies, health care organizations, and insurers.
“I think that all our patients should actually want A.I. technologies to be brought to bear on weaknesses in the health care system, but we need to do it in a non-Silicon Valley hype way,” says Isaac Kohane, a biomedical informatics researcher at Harvard Medical School.
