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Category: health – Page 349

A disease-carrying, newly invasive tick to the United States, the Asian longhorned tick, is poised to spread across much of North America, suggests a new study published Thursday in the Journal of Medical Entomology. According to the study, the tick might be able to live anywhere from Southeastern Canada to most of the eastern half of the U.S. and even parts of the West Coast.

The Asian longhorned tick, or Haemaphysalis longicornis, made an unwelcome splash last year, when researchers and health officials discovered it on a pet sheep in New Jersey. Any hopes that the discovery was an isolated incident faded away this year, with sightings of the tick popping up again in New Jersey and eight other states this past spring and summer (Arkansas, Connecticut, Maryland, New York, North Carolina, Pennsylvania, Virginia, and West Virginia). Since 2017, the tick has been found on pets, farm animals, and at least two people in the U.S., and it’s possible that it might have made its way here at least as early as 2010.

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Of the 10 flavonoids tested, fisetin was the most potent senolytic. Acute or intermittent treatment of progeroid and old mice with fisetin reduced senescence markers in multiple tissues, consistent with a hit-and-run senolytic mechanism.

The natural product fisetin has senotherapeutic activity in mice and in human tissues. Late life intervention was sufficient to yield a potent health benefit. These characteristics suggest the feasibility to translation to human clinical studies.

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In order to advance innovation and keep pace with the rapidly evolving healthcare industry, the US Food and Drug Administration (FDA) is modernizing the approval process most medical device manufacturers undergo when bringing new products to market.

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New research suggests that exposure to childhood adversity is associated with reduced cognitive control and alterations in key brain networks. The findings, which appear in the journal Social Cognitive and Affective Neuroscience, could help explain the link between childhood adversity and depression.

“My work focuses on how we can use objective biomarkers to aid in clinical decision making,” said study author Scott A. Langenecker of the University of Utah.

“One challenging clinical decision point is what to do when individuals have recovered from a depressive episode. Do we continue treatment? Do we exercise regular check-ins? Or do we just wait and see?”

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As local, federal, and international policies targeting the quality of the air we breathe continue to evolve, questions arise of how effective existing policies have been in improving human health. For example, how many lives have been saved by tough air pollution policies? How many illnesses have been caused by lax policies?

US ozone levels map highlighting highest levels

Annual mean levels of fine particulate matter (PM2.5) pollution declined in the United States between 1990 (left) and 2010 (right), leading to thousands of lives saved, according to researcher Jason West.

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Virginia Tech announced Thursday it will receive a record $50 million gift to support biomedical research, a landmark donation for the public university that will expand the influence of its academic health center in Roanoke.

The gift comes from the Horace G. Fralin Charitable Trust and from Heywood and Cynthia Fralin. It is twice as large as the previous record, a $25 million donation from Alice and Bill Goodwin for an engineering building that opened in 2014 on the university’s main campus in Blacksburg.

The new funding will help the university recruit and retain researchers, a spokesman said. A biomedical research institute will be named for the Fralin family and based within the Virginia Tech Carilion Academic Health Center.

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One of the biggest obstacles to transplanting organs from one person to another is that the immune system of the person getting the new life-saving organ often tries to reject it. The immune cells see the new material as “foreign” and attacks it, sometimes destroying it.

Right now, the only way to prevent that is by using powerful immunosuppressive drugs to keep the patient’s immune system at bay and protect the new organ. It’s effective, but it also comes with some long-term health consequences.

But now researchers at Tel Aviv University in Israel say they may have found a way around that, using the patient’s own stem cells.

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