Lifeboat Foundation

Excellent!!! Cannot wait until we eradicate cancer, MS, Parkinson, Dystonia, Cystic-Fibrosis, LGD, etc.

A team of Physicians at the University of Pennsylvania’s School of Medicine now has their project of modifying the immune cells of 18 different cancer patients with the CRISPR-Cas9 system approved by the National Institute of Health.

CRISPR is the gift that keeps on giving—when it’s not fighting blindness, tackling HIV, or even recording real-time immune responses, it is taking on the emperor of all maladies: cancer.

Continue reading “Approved: First Ever Human Trials Involving CRISPR Gene Editing” »

Scientists are one step closer to using CRISPR gene editing on humans, with a US federal advisory panel approving the use of the technique for a study led by the University of Pennsylvania.

The scientists are seeking to use the CRISPR-Cas9 technique to create genetically altered T cells – white blood cells that play an important role in our immune system – that are more effective at fighting cancer cells in patients with melanoma, multiple myeloma, and sarcoma.

“Our preliminary data suggests that we could improve the efficacy of these T cells if we use CRISPR,” lead researcher Carl June told the National Institute of Health’s (NIH) Recombinant DNA Advisory Committee (RAC) on Tuesday.

Continue reading “A federal panel just gave the green light to use gene editing on humans” »

Washington University in St. Louis and Keio University in Japan is set to test the effectiveness and safety of the compound. Starting next month, about 10 healthy people will be administered NMN to see if can improve bodily function and stave off the effects of aging. Should it work, it would become the first bona fide anti-aging intervention available on the market.

A compound called nicotinamide mono nucleotide (NMN) has been shown to slow down the aging process and extend the lifespans of mice. We’re about to find out if it does the same thing to humans.

A planned clinical trial devised by researchers from Washington University in St. Louis and Keio University in Japan is set to test the effectiveness and safety of the compound. Starting next month, about 10 healthy people will be administered NMN to see if can improve bodily function and stave off the effects of aging. Should it work, it would become the first bona fide anti-aging intervention available on the market.

Continue reading “A Promising Anti-Aging Drug Will Soon Be Tried On Humans” »

Want to fight aging; eat this new chocolate.

Cambridge UK (PRWEB UK) 19 June 2016 Lycotec Ltd., a biotech company based in Cambridge UK, http://www.lycotec.com announces that they have developed the World’s First Longevity SIRT Chocolate, which after ingestion provides a blood level of unmodified trans-Resveratrol, t-RSV, equal to its level after drinking red wine.

T-RSV is the molecule of plant polyphenol class which is typically present in red grapes, some berries, cocoa and nuts. There are a number of beneficial health effects of t-RSV from cardioprotective to antidiabetic. However, one of its intriguing properties is the ability to activate a group of SIRT genes. These genes are responsible for controlling cellular stress protection and longevity.

When t-RSV is consumed as part of food, or a beverage, or as an isolated extract in the form of most supplements, it quickly gets modified and inactivated in the digestive tract. Drinking red wine is the only known exception when t-RSV can reach the blood in an unmodified active form at a detectable level.

Continue reading “World’s First Longevity SIRT Chocolate” »

Sperm have been made in the laboratory and used to father healthy baby mice in a pioneering move that could lead to infertility treatments.

The Chinese research took a stem cell, converted it into primitive sperm and fertilised an egg to produce healthy pups.

The study, in the Journal Cell Stem Cell, showed they were all healthy and grew up to have offspring of their own.

Crowdfunding Campaign: https://www.lifespan.io/campaigns/the-major-mouse-testing-program/

We are testing a combination of compounds which clear out dysfunctional cells in the body, called Senolytics, to see if we can extend maximum lifespan and healthspan in mice. Please subscribe, share, and fund our Lifespan.io campaign today!

Continue reading “MMTP — Major Mouse Testing Program — Interview with David Gems” »

WEDNESDAY, June 15, 2016 (HealthDay News) — Brain cancer patients might benefit from an implantable ultrasound device that appears to enhance chemotherapy treatment, a small study says.

Researchers from the Pitie-Salpetriere Hospital in Paris and other French institutions tested the experimental device on 15 patients with recurrent glioblastoma, a particularly deadly brain cancer. When the so-called SonoCloud was activated, sound waves opened the blood-brain barrier, letting in more chemotherapy, they said.

“The walls of the blood vessels in the brain are very difficult to cross for certain molecules,” said Frederic Sottilini, CEO of Paris-based CarThera, the company developing SonoCloud.

Continue reading “Novel Brain Cancer Treatment Taps Into Sound Waves” »

Awesome!

University of Oklahoma researchers will apply a new analytical technology that could ultimately provide a powerful tool for improved treatment of cancer patients in Oklahoma and beyond. Using mass spectrometry, an analytical instrument for sensitive detection and accurate identification of molecules, the team will quantitate the amount of anti-cancer drugs present in individual cancer cells, including those in bladder cancer cells isolated from patients undergoing chemotherapy. The method will provide a means to establish ideal dosing regimens that delivers effective chemotherapeutic concentrations to patients with minimal toxicities.

Anthony Burgett and Zhibo Yang, assistant professors in the Department of Chemistry and Biochemistry in the OU College of Arts and Sciences, and affiliates of the Stephenson Cancer Center, in collaboration with Jonathan E. Heinlen, M.D., assistant professor in the Department of Urology at the OU Health Sciences Center and a Stephenson Cancer Center researcher, will fully develop the novel first-in-class mass spectrometric technology—the Single Probe—capable of performing single-cell mass spectrometry of compounds inside of living single cancer cells as a bioanalytical method to improve efficacy and toxicities of chemotherapy in patients.

Continue reading “New analytical technology could improve cancer treatment” »

Boosting the transport of mitochondria (cell energy suppliers) along neuronal axons enhances the ability of mouse nerve cells to repair themselves and regrow after injury or disease, researchers at the National Institute of Neurological Disorders and Stroke report in The Journal of Cell Biology.

Neurons need large amounts of energy to extend their axons long distances through the body. This energy — in the form of adenosine triphosphate (ATP) — is provided by mitochondria.

Continue reading “Mobilizing mitochondria to regenerate damaged neurons” »