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Archive for the ‘health’ category: Page 415

Mar 13, 2016

Welcome to Major Mouse Testing Project | Major Mouse Testing Project

Posted by in categories: bioengineering, biotech/medical, health, life extension

SENS has kindly commented about MMTP and the impact our research should have on aging. We launch a fundraiser in April to test senolytics (ApoptoSENS) with a planned follow up to combine this with stem cell therapy (RepleniSENS). It is time to put the engineering approach to aging to the test!


Some drugs tested have been found to increase mouse lifespan such as Metformin and Rapamycin for example and are considered for human testing. Many more substances have never been tested and we do not know if they might extend healthy lifespan.

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Mar 10, 2016

Machine learning underpins data-driven AI: Una-May O’Reilly

Posted by in categories: biotech/medical, computing, health, information science, robotics/AI

Another data scientist with pragmatic thinking which is badly needed today. Keeping it real with Una-May O’Reilly.


Mumbai: Una-May O’Reilly, principal research scientist at Anyscale Learning For All (ALFA) group at the Massachusetts Institute of Technology Computer Science and Artificial Intelligence Laboratory, has expertise in scalable machine learning, evolutionary algorithms, and frameworks for large-scale, automated knowledge mining, prediction and analytics. O’Reilly is one of the keynote speakers at the two-day EmTech India 2016 event, to be held in New Delhi on 18 March.

In an email interview, she spoke, among other things, about how machine learning underpins data-driven artificial intelligence (AI), giving the ability to predict complex events from predictive cues within streams of data. Edited excerpts:

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Mar 9, 2016

Can chocolate make you smarter? (And thinner? And healthier?)

Posted by in categories: health, neuroscience

A new study claims chocolate can improve cognitive performance – joining research that indicates it can prevent heart attacks and help you lose weight. But dig a little deeper and all is not what it seems …

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Mar 9, 2016

‘Artificial pancreas’ is one of new tech devices aimed at diabetes

Posted by in categories: biotech/medical, health, mobile phones, robotics/AI, wearables

Wearables and other connected devices have been available to help treat chronic conditions like asthma and heart disease for a while now. But thus far, the nation’s 30 million diabetics haven’t seen much to help them improve their health or reduce the daily grind of finger pricks and needle pokes.

The $2.5 billion connected-care industry may be off to a late start in diabetes, but it’s making up for lost time. A new breed of connected glucometers, insulin pumps and smartphone apps is hitting the market. They promise to make it easier for diabetics to manage the slow-progressing disease and keep them motivated with feedback and support. In as little as two years, the industry plans to take charge of the entire uncomfortable, time-consuming routine of checking and regulating blood-sugar levels with something called an artificial pancreas. Such systems mimic the functions of a healthy pancreas by blending continuous glucose monitoring, remote-controlled insulin pumps and artificial intelligence to maintain healthy blood-sugar levels automatically.

For Jeroen Tas, CEO of Philips’ Connected Care and Health Informatics unit, diabetes management is also personal: his daughter Kim is diabetic.

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Mar 9, 2016

NIH awards grant to upstart for nanotech, regenerative spinal implants

Posted by in categories: biotech/medical, health, nanotechnology

New funding awarded by DARPA on new spinal implants; this should make some commercial pilots that I know happy.


Carmel, IN-based startup Nanovis is no stranger to nabbing research grants. It’s just nabbed one from the National Institutes of Health for preclinical research on the use of its porous Forticore interbody fusion devices in combination with nanotube technology. The combination is expected to result in a surface that mimics nature and encourages regeneration around an implant.

Nanovis has previously gotten 8 competitive peer-reviewed grants from the NIH and other research organizations; this is its second NIH grant. In September 2014, it got FDA clearance for its FortiCore interbody fusion devices and then last October it launched an expanded FortiCore line.

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Mar 9, 2016

You can now sequence your entire genome for under $1,000

Posted by in categories: biotech/medical, genetics, health

It wasn’t all that long ago that the first human genome was sequenced – a massive, globally orchestrated scientific undertaking that took years and some US$3 billion to achieve.

Since then, rapid advancements in genetic technology and techniques have seen the cost and time required for genome sequencing drop dramatically, leading to this week’s remarkable announcement: the first whole genome sequencing service for consumers that costs less than $1,000.

At just $999, myGenome, from US-based genetics startup Veritas Genetics, is being billed by its makers as the first practical and affordable way for people to access unparalleled personal data on their individual genetic code. The company claims its personalised service offers an accessible way to keep tabs on your current health, keep you abreast of any potential future issues, and even know what inherited genetics you might pass onto your children.

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Mar 9, 2016

Death Reversal — The Reanima Project — Research Whose Time Has Come

Posted by in categories: aging, biotech/medical, business, cryonics, health, life extension, neuroscience, posthumanism, science, scientific freedom

I have spent the last 30 years in various aspects of the biopharmaceutical industry, which for the most part has been a very rewarding experience.

However, during this time period, having been immersed many different components of therapeutic development and commercialization, one thing has always bothered me: a wide array of promising research never makes it off the bench to see the translational light of day, and gets lost in the historical scientific archives.

bqiinclab

I always believed that scientific progress happened in a very linear narrative, with each new discovery supporting the next, resulting ultimately in an eventual stairway of scientific enlightenment.

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Mar 8, 2016

Laser grown directly on a silicon substrate

Posted by in categories: energy, health

Creation of first practical silicon-based laser has the potential to transform communications, healthcare and energy systems.

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Mar 7, 2016

The Importance of Hope

Posted by in categories: biological, education, health, homo sapiens, life extension

hope

I learn useful life lessons from each patient I meet. Some are positive messages, reminding me of the importance of maintaining balance between family, work, and leisure activities, but more frequently I witness examples of the remarkable resilience of the human spirit when facing the reality and risks of a major surgical procedure and a diagnosis of cancer. Rarely, patients and their family members utter remorseful or simply sad remarks when they are faced with a grim prognosis and the emotions associated with an onrushing date with mortality. These comments invariably involve an inventory of regrets in life, including, “I should have spent more time with my kids,” “I wish I had told my father (or mother, brother, sister, child, or some other person) that I loved them before they died,” and “I have spent my entire life working, I never took time for anything else.” I wince when I hear these openly expressed remonstrations, I recognize that I am hearing painful and heartfelt truths. Not a week goes by that I am not reminded that I do not one day want to look back at my life with a long list of regrets, should have dones, and what ifs.

I was blessed to meet a great teacher in the guise of a patient early in my academic career. He came to my clinic in my first year after completing a Fellowship in Surgical Oncology, my first year as an Assistant Professor of Surgery. My patient was a 69 year-old Baptist Minister from a small town in Mississippi. He was referred to me by his medical oncologist who called me and said, “I don’t think there is anything you can do for him, but he needs to hear that from you because he doesn’t believe me.” This tall, imposing man had colon cancer that had metastasized (spread) to his liver. The malignant tumor in his colon was removed the year before I met him, and he had received chemotherapy to treat several large tumors found in his liver. The chemotherapy had not worked and the tumors grew. At the point I met him, the medical oncologist told him he would live no more than 6 months, and because he was an avid fisherman when not preaching or helping others in his community , the doctor suggested that he go out and enjoy his remaining time by getting in as much fishing as possible. I learned two invaluable lessons from this patient and his family. First, never deny or dismiss hope from a patient or their family, even when from a medical perspective the situation seems hopeless and the patient is incurable. Second, quoting the minister directly, “Some doctors think of themselves as gods with a small ‘g’, but not one of you is God”.

When I first walked into the examining room, this man was slouched on the examining table in the perfunctory blue and white, open-backed, always unflattering hospital gown. He made eye contact with me briefly, then looked down to the floor. In that momentary meeting of our eyes, I saw no sparkle, no life, no hope in his eyes. He responded to my initial questions with a monotonic and quiet voice. Several times I had to ask him to repeat an answer because his response was so muted. Mid-way through our first visit, the patient’s wife told me he had been very depressed by his diagnosis of untreatable metastatic colon cancer. She reported, despite his occasional side-long warning glances requesting her silence, that while he was eating well, he was spending most of his time sitting in a chair or laying in bed, and that the active, gregarious man with the quick wit and booming voice she had married was gone.

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Mar 6, 2016

3D-Printed Drugs Coming Soon

Posted by in categories: 3D printing, biotech/medical, health

Frankly, in the US this makes me really nervous. Placing drug making 3D printers in your local pharmacies. I hope that the manufacturer has a mechanism setup to cause the machine not to work if it is stolen by the local drug gangs.


The brave new world of 3D-printed drugs in the healthcare industry is heating up.

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