Lifeboat Foundation

It’s safe to say that VCs struck while the iron was hot this year where it concerned generative AI.

A recent report from Pitchbook shows that ‘mega-deals’ could be inflating AI startup funding totals, giving a misleading picture of the sector’s health.

So our experiences or how we handle those experiences may have an effect on the expression of genes in our body.

A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.

It’s already known that head injuries are common in young kids, especially from falling, and can be linked to mood disorders and social difficulties that emerge later in life. Adverse childhood experiences are also very common, and can raise risk for disease, mental illness and substance misuse in adulthood.

Continue reading “Stress Changes More Genes in the Mouse Brain Than a Head Injury” »

I have to start eating that. Wasabi, a great memory booster.

A researcher behind a study of wasabi’s effect on cognition says he knew the fiery condiment had health benefits, but “the dramatic change” in memory was a surprise.

A new study in mice, published recently in the journal Cell Metabolism, shows that cutting down the amount of a single amino acid called isoleucine can, among other benefits, extend their lifespan, make them leaner and less frail as they age and reduce cancer and prostate problems, all while the mice ate more calories.

There’s a popular saying in some circles that “a calorie is a calorie,” but science shows that it may not be true. In fact, it may be possible to eat more of some kinds of calories while also improving your health.

“We like to say a calorie is not just a calorie,” says Dudley Lamming, a professor and metabolism researcher at the University of Wisconsin School of Medicine and Public Health. “Different components of your diet have value and impact beyond their function as a calorie, and we’ve been digging in on one component that many people may be eating too much of.”

“We’re looking at a race, a race between China, between IBM, Google, Microsoft, Honeywell,” Kaku said. “All the big boys are in this race to create a workable, operationally efficient quantum computer. Because the nation or company that does this will rule the world economy.”

It’s not just the economy quantum computing could impact. A quantum computer is set up at Cleveland Clinic, where Chief Research Officer Dr. Serpil Erzurum believes the technology could revolutionize the world of health care.

Quantum computers can potentially model the behavior of proteins, the molecules that regulate all life, Erzurum said. Proteins change their shape to change their function in ways that are too complex to follow, but quantum computing could change that understanding.

It causes the air sacs of the lungs to fill up with fluid or pus. It can range from mild to severe, depending on the type of germ causing the infection, your age, and your overall health.

What causes pneumonia?

Bacterial, viral, and fungal infections can cause pneumonia.

After five years, more than 350,000 hours of genome sequencing, and over £200 million of investment, UK Biobank is releasing the world’s largest-by-far single set of human sequencing data—completing the most ambitious project of its kind ever undertaken. The new data, whole genome sequences of its half a million participants, will certainly drive the discovery of new diagnostics, treatments, and cures. Uniquely, the data are available to approved researchers worldwide, via a protected database containing only de-identified data.

This advance lies not only in the abundance of genomic data, but its use in combination with the existing data UK Biobank has collected over the past 15 years on lifestyle, whole body imaging scans, health information, and proteins found in the blood. The Pharma Proteomics Project was published last month in Nature, in the paper, “Plasma proteomic associations with genetics and health in the UK Biobank.”

Looking forward, these data could be used to further advance efforts such as more targeted drug discovery and development, discovering thousands of disease-causing noncoding genetic variants, accelerating precision medicine, and understanding the biological underpinnings of disease.

A tiny but prolific world of microbes encompasses everything around us, both inside and out. Microbiomes, which are comprised of diverse communities of microbes, play a pivotal role in shaping human health, yet the intricacies of how different microbial compositions influence our well-being remain largely unknown.

In a recent study published in Proceedings of the National Academy of Sciences, researchers at the University of Illinois Urbana-Champaign describe a new framework they have created to predict how species within microbiomes interact with each other to create unique compositions.

“Microbes can be used in medicine, aka ‘bugs as drugs,’ and these microbial therapeutics hold the possibility of being the answer to many of the diseases we face today,” said Shreya Arya, a graduate student in the O’Dwyer lab.

Large language models such as that used by ChatGPT could soon become essential tools for diagnosing and treating patients. To protect people’s privacy and safety, medical professionals, not commercial interests, must drive their development and deployment.