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Category: health – Page 8

It’s time to think about human reproduction in space, scientists urge

There are currently no widely accepted, industry-wide standards for managing reproductive health risks in space, the study notes. The researchers highlight unresolved questions around preventing inadvertent early pregnancy during missions, understanding the fertility impacts of microgravity and radiation, and setting ethical boundaries for any future reproduction-related research beyond Earth.

“If reproduction is ever to occur beyond Earth,” the study notes, “it must do so with a clear commitment to safety, transparency and ethical integrity.”

This research is described in a paper published Feb. 3 in the journal Reproductive Biomedicine Online.

A Virus Designed in the Lab Could Help Defeat Antibiotic Resistance

Scientists can now design bacteria-killing viruses from DNA, opening a faster path to fighting superbugs.

Bacteriophages have been used as treatments for bacterial infections for more than a century. Interest in these viruses is rising again as antibiotic-resistant infections become an increasing threat to public health. Even so, progress in the field has been slow. Most research has relied on naturally occurring phages because traditional engineering methods are time consuming and difficult, limiting the development of customized therapeutic viruses.

A fully synthetic phage engineering breakthrough.

A simple blood test could change how Alzheimer’s is diagnosed

A blood test, combined with an ultrathin material derived from graphite, could significantly advance efforts to detect Alzheimer’s disease at its very earliest stage, even before symptoms appear.

Alzheimer’s disease is the most common form of dementia. For millions of Europeans—and the health services that care for them—it is a ticking time bomb, with still no cure. But EU researchers are developing a simple tool to enable much earlier detection, potentially decades before symptoms appear.

Early detection matters because treatment is most effective when started as soon as possible. This gives people a better chance to slow the progression of the disease and plan for the future. Today, around 7 million people in Europe live with Alzheimer’s, a number expected to double by 2030, according to the European Brain Council.

Reproduction in space, an environment hostile to human biology

As commercial spaceflight draws ever closer and time spent in space continues to extend, the question of reproductive health beyond the bounds of planet Earth is no longer theoretical but now “urgently practical,” according to a new study published in the journal Reproductive Biomedicine Online.

“More than 50 years ago,” explains clinical embryologist Giles Palmer from the International IVF Initiative Inc, “two scientific breakthroughs reshaped what was thought biologically and physically possible—the first moon landing and the first proof of human fertilization in vitro.

Now, more than half a century later, we argue in this report that these once-separate revolutions are colliding in a practical and underexplored reality: space is becoming a workplace and a destination, while assisted reproductive technologies have become highly advanced, increasingly automated and widely accessible.

A programmable, Lego-like material for robots emulates life’s flexibility

Mechanical engineers at Duke University have demonstrated a proof-of-concept method for programming mechanical properties into solid Lego-like building blocks. By controlling the solidity of hundreds of individual cells in specific patterns, the approach could allow futuristic robotics to alter their mechanical properties and functionalities on the fly.

In their initial tests, the researchers showed how a tail-like 3D beam with various configurations can move a robotic fish through water along different paths with the same motor activity. The team envisions miniaturized versions of the technology that could, for example, maneuver through blood vessels to survey their health or even reconfigure to form an adaptive stent.

The research appears in the journal Science Advances.

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

A new study found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris. Without this enzyme, monocytes enter tissues but fail to fully differentiate, leading to impaired tissue maintenance and persistent immune cell infiltration that causes inflammation instead of repair.

The research, published in Nature, showed that deoxyhypusine synthase (DHPS) is required for both the differentiation and long-term survival of macrophages across multiple organs, including the lung, liver, brain, kidney, heart and peritoneal cavity.

Using a series of mouse models, the investigators demonstrated that DHPS controls a core, tissue-agnostic program that enables macrophages to adhere to their local environment, interact with surrounding cells and carry out the essential functions that maintain tissue balance and organ health.

The researchers traced these defects to the polyamine–hypusine pathway. Analyses of gene activity, protein production and protein-making machinery revealed that DHPS is required for efficient translation of a subset of genes involved in cell adhesion (the ability to stick to their surroundings and to other cells so they can stay in the correct place and function properly), signaling, and tissue interaction. Without DHPS, macrophages failed to express key proteins needed to anchor themselves within tissues and respond appropriately to local cues.

Imaging studies showed that DHPS-deficient macrophages had abnormal shape and positioning within tissues, while functional assays demonstrated defects in the clearance of dead cells and tissue maintenance. In the lung, this impairment led to accumulation of surfactant material, a substance in the lungs that keeps air sacs open, and immune cell infiltration, while in the liver, acute macrophage depletion followed by failed restoration resulted in vascular disruption and tissue damage. sciencenewshighlights ScienceMission.

Study Reveals a Turning Point When Men’s Heart Attack Risk Accelerates

Screening at an earlier age can help identify risk factors sooner, enabling preventive strategies that reduce long-term risk.

Screening for heart attack risk should be happening earlier for men, according to a new study that found the risk of cardiovascular disease starts climbing when men are in their mid-30s – significantly earlier than a similar trend is seen in women.

The US-based researchers behind the study followed the health of 5,112 people for an average of around 34 years. As the participants were healthy and aged 18–30 when the study started in the mid-1980s, the researchers could chart cases of cardiovascular disease (including strokes and heart failure) over time.

According to the data, 35 is the critical age when disparities between male and female cardiovascular disease risk start to appear. Most of the difference is driven by coronary heart disease (CHD), the most common cause of heart attacks, where fatty deposits clog up arteries, blocking blood flow.

Newly identified RNA molecule may drive cancer patient survival

In a recent study, researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA molecule that plays a crucial role in preserving the integrity of a key cellular structure, the nucleolus. Their findings also suggest this molecule may influence patient survival in certain blood cancers. The work is published in the Proceedings of the National Academy of Sciences.

Machine learning accelerates plasma mirror design for high-power lasers

Plasma mirrors capable of withstanding the intensity of powerful lasers are being designed through an emerging machine learning framework. Researchers in Physics and Computer Science at the University of Strathclyde have pooled their knowledge of lasers and artificial intelligence to produce a technology that can dramatically reduce the time it takes to design advanced optical components for lasers—and could pave the way for new discoveries in science.

High-power lasers can be used to develop tools for health care, manufacturing and nuclear fusion. However, these are becoming large and expensive due to the size of their optical components, which is currently necessary to keep the laser beam intensity low enough not to damage them. As the peak power of lasers increases, the diameters of mirrors and other optical components will need to rise from approximately one meter to more than 10 meters. These would weigh several tons, making them difficult and expensive to manufacture.

Scientists Identified a New Blood Group After a 50-Year Mystery

It represents a huge achievement, and the culmination of a long team effort.

A pregnant woman’s blood sample taken in 1972 was mysteriously missing a surface molecule found on all other known red blood cells at the time.

More than 50 years later, that strange absence finally led researchers from the UK and Israel to describe a new blood group system in humans. The team published a paper on the discovery in 2024.

“It represents a huge achievement, and the culmination of a long team effort, to finally establish this new blood group system and be able to offer the best care to rare, but important, patients,” hematologist Louise Tilley from the UK National Health Service said in September 2024, after nearly 2 decades of personally researching this bloody quirk.

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