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Crispr Innovators Make It Easier to Use Their Gene-Editing Technology

Two important developers of the celebrated Crispr gene-editing technology said they will make it easier for researchers to license their intellectual property, a move aimed at hastening innovation in the burgeoning field.

MilliporeSigma, the life-sciences tools division of German pharmaceutical giant Merck KGaA, and the Broad Institute of MIT and Harvard said researchers will be able to get nonexclusive rights to patents held by both organizations for research purposes with a single license.

Companies will have to pay a licensing fee. Nonprofit and academic institutions will be permitted to license the patents for free, the organizations said in a news release on Thursday.

Study gives insight into sun-induced DNA damage and cell repair

A team led by a Baylor University researcher has published a breakthrough article that provides a better understanding of the dynamic process by which sunlight-induced DNA damage is recognized by the molecular repair machinery in cells as needing repair.

Ultraviolet light from the sun is a ubiquitous carcinogen that can inflict structural damage to the cellular DNAs DNA carries important blueprints for cellular functions, failure in removing and restoring damaged parts of DNA in a timely fashion can have detrimental outcomes and lead to skin cancers in humans, said lead author Jung-Hyun Min, Ph.D., associate professor of chemistry and biochemistry in Baylor’s College of Arts & Sciences.

Min and her team showed how the repair Rad4/XPC would bind to one such UV-induced DNA damage—6–4 photoproduct—to mark the damaged site along the DNA in preparation for the rest of the nucleotide excision repair (NER) process in cells.

Invention: Plasma-powered flying saucer

By Justin MullinsPass a current or magnetic field through a conducting fluid and it will generate a force. Numerous aerospace engineers have tried and failed to exploit this phenomenon, known as magnetohydrodynamics, as an exotic form of propulsion for aircraft. But perhaps attempts so far have all been too big.

A very small design could have a better chance of taking off, says Subrata Roy, an aerospace engineer at the University of Florida, Gainesville, US.

With a span of less than 15 centimetres, his aircraft qualifies as a micro air vehicle (MAV), but it has an unconventional design to say the least. It is a saucer shape covered with electrodes that ionise air to create a plasma. This plasma is then accelerated by an electric field to push air around and generate lift.